Detail Information

Basic Information:


  VIRBase ID:  

VHID00501984

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7903

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           CAMK2B:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p CAMK2B
miRBase
Accession/Entrez ID		 MIMAT0001581 816
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - CAM2//CAMK2//CAMKB//CaMKIIbeta//MRD54

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CAMK2B
chr7:44347562(-) A-I      intronic
chr7:44262218(-) A-I      intronic
chr7:44341219(-) A-I      intronic
chr7:44290234(-) A-I      intronic
chr7:44341009(-) A-I      intronic
chr7:44287565(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CAMK2B
chr7:44257125-44257126(-) m6A 3'UTR       -
chr7:44257147-44257148(-) m6A 3'UTR       22575960
chr7:44257189-44257190(-) m6A 3'UTR       22575960
chr7:44257200-44257201(-) m6A 3'UTR       22575960
chr7:44257220-44257221(-) m6A 3'UTR       22575960
chr7:44257250-44257251(-) m6A 3'UTR       22575960
chr7:44257263-44257264(-) m6A 3'UTR       22575960
chr7:44257278-44257279(-) m6A 3'UTR       22575960
chr7:44257289-44257290(-) m6A 3'UTR       22575960
chr7:44257303-44257304(-) m6A 3'UTR       22575960
chr7:44257308-44257309(-) m6A 3'UTR       22575960
chr7:44258758-44258759(-) m6A 3'UTR//intron       22608085
chr7:44258764-44258765(-) m6A 3'UTR//intron       22608085
chr7:44258774-44258775(-) m6A 3'UTR//intron       22608085
chr7:44258873-44258874(-) m6A 3'UTR//intron       22608085
chr7:44258882-44258883(-) m6A 3'UTR//intron       22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate CAMK2B
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: CAMK2B

Evidence Support:


Strong-Evidence RISC-IP
Prediction-Evidence miRanda//PITA
Support Database ViRBase//VmiReg

References:


PMID 20585629 Target region 5'UTR
Source ViRBase//VmiReg Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

Starting a new search, please wait ...