Detail Information

Basic Information:


  VIRBase ID:  

VHID00501893

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:           BST2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hcmv-miR-US25-1-5p BST2
miRBase
Accession/Entrez ID		 MIMAT0001581 684
Organism Human herpesvirus 5 strain AD169 Homo sapiens
Category miRNA mRNA
Alias - CD317//HM1.24//TETHERIN

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR BST2
chr19:17512145(-) A-I      intronic
chr19:17512156(-) A-I      intronic
chr19:17510983(-) A-I      intronic
chr19:17512758(-) A-I      intronic
chr19:17512713(-) A-I      intronic
chr19:17512211(-) A-I      intronic
chr19:17512164(-) A-I      intronic
chr19:17512759(-) A-I      intronic
chr19:17510977(-) A-I      intronic
chr19:17512939(-) A-I      intronic
chr19:17512036(-) A-I      intronic
chr19:17510967(-) A-I      intronic
chr19:17510965(-) A-I      intronic
chr19:17510927(-) A-I      intronic
chr19:17509551(-) A-I      intronic
chr19:17509524(-) A-I      intronic
chr19:17509358(-) A-I      intronic
chr19:17507840(-) A-I      intronic
chr19:17507805(-) A-I      intronic
chr19:17507773(-) A-I      intronic
chr19:17507671(-) A-I      intronic
chr19:17507546(-) A-I      intronic
chr19:17504287(-) A-I      intronic
chr19:17504294(-) A-I      intronic
chr19:17507777(-) A-I      intronic
chr19:17512063(-) A-I      intronic
chr19:17507533(-) A-I      intronic
chr19:17507526(-) A-I      intronic
chr19:17507135(-) A-I      intronic
chr19:17506766(-) A-I      intronic
chr19:17506750(-) A-I      intronic
chr19:17506744(-) A-I      intronic
chr19:17506726(-) A-I      intronic
chr19:17506676(-) A-I      intronic
chr19:17506665(-) A-I      intronic
chr19:17506640(-) A-I      intronic
chr19:17506572(-) A-I      intronic
chr19:17506516(-) A-I      intronic
chr19:17506407(-) A-I      intronic
chr19:17505720(-) A-I      intronic
chr19:17505576(-) A-I      intronic
chr19:17505458(-) A-I      intronic
chr19:17505426(-) A-I      intronic
chr19:17504270(-) A-I      intronic
chr19:17503742(-) A-I      intronic
chr19:17503683(-) A-I      intronic
chr19:17503651(-) A-I      intronic
chr19:17503569(-) A-I      intronic
chr19:17503556(-) A-I      intronic
chr19:17503216(-) A-I      intronic
chr19:17503185(-) A-I      intronic
chr19:17511174(-) A-I      intronic
chr19:17511191(-) A-I      intronic
chr19:17511217(-) A-I      intronic
chr19:17511218(-) A-I      intronic
chr19:17503203(-) A-I      intronic
chr19:17511255(-) A-I      intronic
chr19:17511311(-) A-I      intronic
chr19:17511313(-) A-I      intronic
chr19:17511316(-) A-I      intronic
chr19:17511326(-) A-I      intronic
chr19:17511353(-) A-I      intronic
chr19:17511865(-) A-I      intronic
chr19:17511866(-) A-I      intronic
chr19:17511880(-) A-I      intronic
chr19:17511045(-) A-I      intronic
chr19:17510951(-) A-I      intronic
chr19:17511893(-) A-I      intronic
chr19:17511897(-) A-I      intronic
chr19:17511933(-) A-I      intronic
chr19:17512003(-) A-I      intronic
chr19:17512059(-) A-I      intronic
chr19:17512105(-) A-I      intronic
chr19:17512109(-) A-I      intronic
chr19:17512165(-) A-I      intronic
chr19:17512245(-) A-I      intronic
chr19:17512269(-) A-I      intronic
chr19:17512326(-) A-I      intronic
chr19:17512357(-) A-I      intronic
chr19:17512773(-) A-I      intronic
chr19:17512858(-) A-I      intronic
chr19:17512865(-) A-I      intronic
chr19:17512914(-) A-I      intronic
chr19:17512915(-) A-I      intronic
chr19:17510874(-) A-I      intronic
chr19:17510847(-) A-I      intronic
chr19:17510537(-) A-I      intronic
chr19:17510468(-) A-I      intronic
chr19:17510330(-) A-I      intronic
chr19:17509547(-) A-I      intronic
chr19:17509518(-) A-I      intronic
chr19:17509382(-) A-I      intronic
chr19:17509345(-) A-I      intronic
chr19:17509154(-) A-I      intronic
chr19:17508540(-) A-I      intronic
chr19:17512975(-) A-I      intronic
chr19:17513231(-) A-I      intronic
chr19:17513177(-) A-I      intronic
chr19:17506561(-) A-I      intronic
chr19:17513153(-) A-I      intronic
chr19:17513121(-) A-I      intronic
chr19:17513111(-) A-I      intronic
chr19:17513095(-) A-I      intronic
chr19:17508468(-) A-I      intronic
chr19:17508398(-) A-I      intronic
chr19:17508397(-) A-I      intronic
chr19:17508005(-) A-I      intronic
chr19:17507996(-) A-I      intronic
chr19:17507985(-) A-I      intronic
chr19:17507973(-) A-I      intronic
chr19:17507960(-) A-I      intronic
chr19:17507919(-) A-I      intronic
chr19:17507817(-) A-I      intronic
chr19:17507798(-) A-I      intronic
chr19:17507764(-) A-I      intronic
chr19:17507732(-) A-I      intronic
chr19:17507693(-) A-I      intronic
chr19:17507669(-) A-I      intronic
chr19:17507651(-) A-I      intronic
chr19:17507579(-) A-I      intronic
chr19:17507573(-) A-I      intronic
chr19:17507565(-) A-I      intronic
chr19:17507552(-) A-I      intronic
chr19:17507537(-) A-I      intronic
chr19:17505688(-) A-I      intronic
chr19:17507876(-) A-I      intronic
chr19:17509741(-) A-I      intronic
chr19:17511269(-) A-I      intronic
chr19:17507093(-) A-I      intronic
chr19:17511831(-) A-I      intronic
chr19:17511037(-) A-I      intronic
chr19:17512837(-) A-I      intronic
chr19:17510410(-) A-I      intronic
chr19:17503222(-) A-I      intronic
chr19:17508556(-) A-I      intronic
chr19:17505485(-) A-I      intronic
chr19:17507875(-) A-I      intronic
chr19:17510331(-) A-I      intronic
chr19:17511190(-) A-I      intronic
chr19:17506725(-) A-I      intronic
chr19:17505537(-) A-I      intronic
chr19:17511861(-) A-I      intronic
chr19:17509359(-) A-I      intronic
chr19:17505563(-) A-I      intronic
chr19:17512028(-) A-I      intronic
chr19:17507752(-) A-I      intronic
chr19:17506398(-) A-I      intronic
chr19:17509548(-) A-I      intronic
chr19:17510991(-) A-I      intronic
chr19:17507913(-) A-I      intronic
chr19:17510963(-) A-I      intronic
chr19:17503223(-) A-I      intronic
chr19:17506502(-) A-I      intronic
chr19:17507589(-) A-I      intronic
chr19:17511804(-) A-I      intronic
chr19:17505750(-) A-I      intronic
chr19:17511421(-) A-I      intronic
chr19:17512283(-) A-I      intronic
chr19:17509363(-) A-I      intronic
chr19:17512202(-) A-I      intronic
chr19:17506774(-) A-I      intronic
chr19:17503655(-) A-I      intronic
chr19:17513033(-) A-I      intronic
chr19:17506664(-) A-I      intronic
chr19:17507742(-) A-I      intronic
chr19:17507066(-) A-I      intronic
chr19:17504345(-) A-I      intronic
chr19:17503629(-) A-I      intronic
chr19:17510476(-) A-I      intronic
chr19:17507656(-) A-I      intronic
chr19:17505719(-) A-I      intronic
chr19:17511836(-) A-I      intronic
chr19:17506975(-) A-I      intronic
chr19:17511433(-) A-I      intronic
chr19:17507786(-) A-I      intronic
chr19:17512877(-) A-I      intronic
chr19:17512135(-) A-I      intronic
chr19:17512895(-) A-I      intronic
chr19:17508010(-) A-I      intronic
chr19:17509414(-) A-I      intronic
chr19:17507479(-) A-I      intronic
chr19:17512329(-) A-I      intronic
chr19:17510407(-) A-I      intronic
chr19:17504314(-) A-I      intronic
chr19:17506666(-) A-I      intronic
chr19:17511169(-) A-I      intronic
chr19:17512110(-) A-I      intronic
chr19:17507617(-) A-I      intronic
chr19:17512933(-) A-I      intronic
chr19:17505593(-) A-I      intronic
chr19:17511252(-) A-I      intronic
chr19:17510464(-) A-I      intronic
chr19:17511278(-) A-I      intronic
chr19:17503763(-) A-I      intronic
chr19:17509142(-) A-I      intronic
chr19:17511352(-) A-I      intronic
chr19:17503746(-) A-I      intronic
chr19:17505390(-) A-I      intronic
chr19:17512055(-) A-I      intronic
chr19:17511335(-) A-I      intronic
chr19:17507168(-) A-I      intronic
chr19:17510940(-) A-I      intronic
chr19:17506998(-) A-I      intronic
chr19:17503717(-) A-I      intronic
chr19:17510574(-) A-I      intronic
chr19:17511372(-) A-I      intronic
chr19:17509200(-) A-I      intronic
chr19:17504435(-) A-I      intronic
chr19:17506698(-) A-I      intronic
chr19:17512111(-) A-I      intronic
chr19:17511345(-) A-I      intronic
chr19:17512007(-) A-I      intronic
chr19:17503163(-) A-I      intronic
chr19:17509674(-) A-I      intronic
chr19:17512719(-) A-I      intronic
chr19:17512746(-) A-I      intronic
chr19:17512294(-) A-I      intronic
chr19:17507633(-) A-I      intronic
chr19:17510891(-) A-I      intronic
chr19:17507524(-) A-I      intronic
chr19:17507807(-) A-I      intronic
chr19:17507478(-) A-I      intronic
chr19:17512732(-) A-I      intronic
chr19:17511964(-) A-I      intronic
chr19:17503704(-) A-I      intronic
chr19:17504411(-) A-I      intronic
chr19:17509401(-) A-I      intronic
chr19:17507768(-) A-I      intronic
chr19:17512203(-) A-I      intronic
chr19:17503209(-) A-I      intronic
chr19:17505391(-) A-I      intronic
chr19:17507772(-) A-I      intronic
chr19:17505469(-) A-I      intronic
chr19:17507100(-) A-I      intronic
chr19:17510996(-) A-I      intronic
chr19:17509362(-) A-I      intronic
chr19:17512814(-) A-I      intronic
chr19:17505539(-) A-I      intronic
chr19:17513081(-) A-I      intronic
chr19:17509652(-) A-I      intronic
chr19:17505453(-) A-I      intronic
chr19:17505445(-) A-I      intronic
chr19:17507870(-) A-I      intronic
chr19:17512820(-) A-I      intronic
chr19:17510901(-) A-I      intronic
chr19:17510385(-) A-I      intronic
chr19:17504335(-) A-I      intronic
chr19:17507060(-) A-I      intronic
chr19:17510942(-) A-I      intronic
chr19:17512284(-) A-I      intronic
chr19:17511178(-) A-I      intronic
chr19:17513034(-) A-I      intronic
chr19:17512069(-) A-I      intronic
chr19:17513021(-) A-I      intronic
chr19:17511036(-) A-I      intronic
chr19:17503270(-) A-I      intronic
chr19:17506419(-) A-I      intronic
chr19:17511266(-) A-I      intronic
chr19:17504336(-) A-I      intronic
chr19:17512894(-) A-I      intronic
chr19:17505427(-) A-I      intronic
chr19:17512308(-) A-I      intronic
chr19:17503037(-) A-I      intronic
chr19:17510318(-) A-I      intronic
chr19:17503085(-) A-I      intronic
chr19:17506432(-) A-I      intronic
chr19:17509174(-) A-I      intronic
chr19:17511969(-) A-I      intronic
chr19:17503280(-) A-I      intronic
chr19:17512855(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase BST2
chr19:17513914-17513915(-) m6A 3'UTR       22575960
chr19:17513963-17513964(-) m6A 3'UTR       22575960
chr19:17514002-17514003(-) Cm 3'UTR       -
chr19:17514093-17514094(-) m6A 3'UTR//exon       27773536//22575960
chr19:17515269-17515270(-) m6A exon//intron       27371828//22575960
chr19:17515284-17515285(-) m6A exon//intron       27371828//22575960
chr19:17515323-17515324(-) m6A exon//intron       27371828//22575960
chr19:17516403-17516404(-) m6A 5'UTR       24284625//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate BST2
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hcmv-miR-US25-1-5p
Interactor2: BST2

Evidence Support:


Strong-Evidence RISC-IP
Support Database ViRBase

References:


PMID 20585629 Target region 5'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line HEK293 cells Interactor2 expression None
Description Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.

Starting a new search, please wait ...