Basic Information:

  VIRBase ID:  

VHID00501251

  Virus:  

Human herpesvirus 5 strain AD169

  Host:  

Homo sapiens

  Confidence Score:  

0.7311

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      hcmv-miR-US25-1-5p:  MIMAT0001581          LINC01600:  NR_131168     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hcmv-miR-US25-1-5p	LINC01600
miRBase Accession/Entrez ID	MIMAT0001581	154386
Organism	Human herpesvirus 5 strain AD169	Homo sapiens
Category	miRNA	lncRNA
Alias	-	bA145H9.2//C6orf195

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt	PMID
LincSNP 3.0	LINC01600	rs1038335 chr6:2631874 G/T         20159242 rs6930750 chr6:2633440 C/G         20502693 rs17135340 chr6:2623819 A/T         20686565 rs7741647 chr6:2631264 C/T         21355061 rs7750686 chr6:2624867 G/C         21572414 rs9503234 chr6:2626154 C/T         22685416 rs9503233 chr6:2623696 A/G         23259602 rs7771891 chr6:2625070 A/G         - rs7759042 chr6:2628917 T/C         -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	LINC01600	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hcmv-miR-US25-1-5p
Interactor2: LINC01600

Evidence Support:

Strong-Evidence	RISC-IP
Support Database	ViRBase

References:

PMID	20585629	Target region	5'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	HEK293 cells	Interactor2 expression	None
Description	Here, we identify cellular transcript targets of one of the most highly expressed HCMV encoded miRNAs, miR-US25-1, using a recently developed biochemical approach called RISC immunoprecipitation. Strikingly, the majority of identified transcripts contained miR-US25-1 target sites within the 5'UTR rather than the 3'UTR.