Detail Information
Interactor1 | Interactor2 | |
---|---|---|
Symbol | kshv-miR-K12-9-3p | Bclaf1 |
miRBase Accession/Entrez ID |
MIMAT0002185 | 72567 |
Organism | Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV) | Mus musculus |
Category | miRNA | mRNA |
Alias | - | 2610102K23Rik//2700025J07Rik//2810454G14Rik//5730534O06Rik//AI450190//AW556225//Btf//mKIAA0164 |
Resource | Symbol | Editing Position | Change | Genetic Region | ||||||
---|---|---|---|---|---|---|---|---|---|---|
RADAR | Bclaf1 |
|
Resource | Symbol | Editing Position | Change | SeqReg | exReg | PMID | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
DARNED | Bclaf1 |
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Resource | Symbol | ModificationPosition | Type | Genomic Context | PMID | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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RMBase | Bclaf1 |
|
Resource | Symbol | Subcellular Localization | Tissue or Cell Line | PMID |
---|---|---|---|---|
RNALocate | Bclaf1 |
Interactor1: kshv-miR-K12-9-3p | Interactor2: Bclaf1 |
---|
Strong-Evidence | Luciferase reporter assay//RT-PCR//Western blot | |
---|---|---|
Prediction-Evidence | miRanda//PicTar//Targetscan | |
Support Database | ViRBase |
[1]PMID | 19098914 | Target region | 3'UTR |
---|---|---|---|
Source | ViRBase | Interactor1 expression | None |
Tissue or cell line | 293 cells//BCBL-1 cells//BCBL-3 cells//BJAB cells//HUVECs | Interactor2 expression | Downregulation |
Description | Indicate miR-K12-5, miR-K12-9 and miR-K12-10 repression of Bcl-2-associated transcription factor 1, an apoptosis-inducing factor. |
[2]PMID | 21152115 | Target region | 3'UTR |
---|---|---|---|
Source | ViRBase | Interactor1 expression | None |
Tissue or cell line | 293 cells//BCBL-1 cells//BCBL-3 cells//BJAB cells//HUVECs | Interactor2 expression | Downregulation |
Description | More studies from recent reports indicate miR-K12-5, miR-K12-9 and miR-K12-10 repression of Bcl-2-associated transcription factor 1, an apoptosis-inducing factor (238), miR-K12-3 reduction of LRRC8D (leucine rich repeat containing 8 family, member D), a leucin-rich type III transmembrane protein involved in proliferation and activation of lymphocytes, NHP2L1 (non-histone chromosome protein 2-like 1) (239), and a transcription factor NFIB (240), miR-K12-1 inhibition of p21 241 and NFkappaB inhibitor IkappaBalpha (242), miR-K12-4-3p suppression of GEMIN8 (239), miR-K12-10a reduction of TWEAKR (243), miR-K12-1, -6, and -11 decrease of MAF (musculoaponeurotic fibrosarcoma oncogene homolog) (244), K12-4-5p targeting retinoblastoma (Rb)-like protein 2 (Rbl2) and miR-K12-5 and -9*suppressing ORF50 mRNA (245,246). |