Basic Information:

  VIRBase ID:  

VHID00495961

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-5-5p:  MIMAT0015218          SERPINE1:  NM_001386462     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-5-5p	SERPINE1
miRBase Accession/Entrez ID	MIMAT0015218	5054
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	PAI//PAI-1//PAI1//PLANH1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SERPINE1	chr7:100776020(+) A-I      intronic chr7:100776467(+) A-I      intronic chr7:100776495(+) A-I      intronic chr7:100776023(+) A-I      intronic chr7:100776025(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SERPINE1	chr7:100770426-100770427(+) m6A 5'UTR       24284625//24981863//26404942 chr7:100770491-100770492(+) m6A 5'UTR       24284625//24981863//26404942 chr7:100770518-100770519(+) m6A 5'UTR       24284625//26404942 chr7:100771902-100771903(+) m6A CDS       26404942 chr7:100773758-100773759(+) m6A CDS       26404942 chr7:100773872-100773873(+) m6A CDS       26404942 chr7:100773922-100773923(+) m6A CDS       26404942 chr7:100775191-100775192(+) m6A CDS       26404942 chr7:100775247-100775248(+) m6A CDS       26404942 chr7:100779036-100779037(+) Am CDS       - chr7:100780326-100780327(+) m6A CDS       24284625//24209618//26404942//27773535 chr7:100780687-100780688(+) m6A CDS       24284625//24209618//24981863//26404942//27773535 chr7:100780716-100780717(+) m6A CDS       24284625//24209618//24981863//26404942//27773535 chr7:100780750-100780751(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535 chr7:100780755-100780756(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535 chr7:100780781-100780782(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535 chr7:100780833-100780834(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535 chr7:100780861-100780862(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535 chr7:100780879-100780880(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535 chr7:100780900-100780901(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535 chr7:100780913-100780914(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535 chr7:100780934-100780935(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535 chr7:100780979-100780980(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535 chr7:100781001-100781002(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942 chr7:100781053-100781054(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942 chr7:100781087-100781088(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942 chr7:100781126-100781127(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942 chr7:100781216-100781217(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942 chr7:100781348-100781349(+) m6A 3'UTR       24284625 chr7:100781659-100781660(+) m6A 3'UTR       24981863 chr7:100781706-100781707(+) m6A 3'UTR       24981863//26404942 chr7:100781802-100781803(+) m6A 3'UTR       24981863//26404942 chr7:100781808-100781809(+) m6A 3'UTR       24981863//26404942 chr7:100781820-100781821(+) m6A 3'UTR       24981863//26404942 chr7:100781889-100781890(+) m6A 3'UTR       24981863//26404942 chr7:100781894-100781895(+) m6A 3'UTR       24981863//26404942 chr7:100781979-100781980(+) m6A 3'UTR       24284625//26404942 chr7:100782007-100782008(+) m6A 3'UTR       24284625//26404942 chr7:100782050-100782051(+) m6A 3'UTR       24284625//26404942 chr7:100782140-100782141(+) m6A 3'UTR       26404942 chr7:100782163-100782164(+) m6A 3'UTR       26404942 chr7:100782250-100782251(+) m6A 3'UTR       26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	SERPINE1	Cytosol HCC cell line (HepG2)|HeLa-S3 cells     - ER-bound ribosome Cutaneous T-cell lymphoma cell lines (HuT78|SeAx)     19175411 Exosome Blood     - Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-5-5p
Interactor2: SERPINE1

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid
Support Database	VmiReg