Detail Information

Basic Information:


  VIRBase ID:  

VHID00495615

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-5-5p:           H19:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol kshv-miR-K12-5-5p H19
miRBase
Accession/Entrez ID		 MIMAT0015218 283120
Organism Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV) Homo sapiens
Category miRNA lncRNA
Alias - ASM//ASM1//BWS//D11S813E//LINC00008//MIR675HG//NCRNA00008//WT2

RNA Editing:


Resource Symbol Editing Position
Lncediting H19
    chr11: 2016679
    chr11: 2016677

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase H19
chr11:2016419-2016420(-) m6A exon       27773535//22575960
chr11:2016434-2016435(-) m6A exon       27773535//22575960
chr11:2016970-2016971(-) m6A exon       24284625//24981863//27773535//27773536//22575960
chr11:2016981-2016982(-) m6A exon       24284625//27773535//22575960
chr11:2017004-2017005(-) m6A exon       24284625//27773535//22575960
chr11:2017009-2017010(-) m6A exon       24284625//27773535//22575960
chr11:2017179-2017180(-) m6A exon//intron       27773535//22575960
chr11:2017186-2017187(-) m6A exon//intron       24284625//27773535//22575960
chr11:2017251-2017252(-) m6A exon//intron       24284625//27773535//22575960
chr11:2017323-2017324(-) m6A exon//intron       24284625//27773535//22575960
chr11:2017542-2017543(-) m6A exon//intron       24284625//22575960
chr11:2017571-2017572(-) m6A exon//intron       24284625//22575960
chr11:2017930-2017931(-) m6A exon//intron       24284625//27773535//22575960
chr11:2017935-2017936(-) m6A exon//intron       24284625//27773535//22575960
chr11:2017974-2017975(-) m6A exon//intron       24284625//27773535//22575960
chr11:2018027-2018028(-) m6A exon//intron       24284625//27773535//22575960
chr11:2018125-2018126(-) m6A exon//intron       24284625//27773535//27773536//22575960
chr11:2018198-2018199(-) m6A exon//intron       24284625//27773535//22575960
chr11:2018319-2018320(-) m6A exon//intron       24284625//24209618//27773535//22575960
chr11:2018326-2018327(-) m6A exon//intron       24284625//24209618//27773535//22575960
chr11:2018338-2018339(-) m6A exon//intron       24284625//24209618//27773535//22575960
chr11:2018344-2018345(-) m6A exon//intron       24284625//24209618//24981863//27773535//22575960
chr11:2018467-2018468(-) m6A exon//intron       24284625//24981863//27773535//27773536//22575960
chr11:2018541-2018542(-) m6A exon//intron       24284625//27773535//27773536//22575960
chr11:2018646-2018647(-) m6A exon//intron       24284625//27773535//22575960
chr11:2018788-2018789(-) Am exon//intron       -
chr11:2018834-2018835(-) m6A exon//intron       24284625//24209618//24981863//27773535//22575960
chr11:2018945-2018946(-) m6A exon//intron       24284625//24209618//25456834//24981863//27773535//22575960
chr11:2019012-2019013(-) m6A exon//intron       24284625//25456834//24981863//27773535//22575960
chr11:2019028-2019029(-) m6A exon//intron       24284625//25456834//24981863//27773535//22575960
chr11:2019081-2019082(-) m6A exon//intron       24284625//24981863//22575960
chr11:2022528-2022529(-) m6A exon       25456834
chr11:2022580-2022581(-) m6A exon       25456834
chr11:2022588-2022589(-) m6A exon       25456834
chr11:2022635-2022636(-) m6A exon       25456834
chr11:2022649-2022650(-) m6A exon       25456834
chr11:2022690-2022691(-) m6A exon       25456834

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate H19
Cytoplasm HaCaT human keratinocyte cell line     32524335
Cytoplasm Cell lines (HeLaS3|HepG2|K562)     22955988
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Serum     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR H19
Vincristine 5978 Drug resistant
Etoposide 36462 Drug resistant
Doxorubicin 31703 Drug resistant
Doxorubicin 31703 Drug resistant
Verapamil 2520 Drug resistant
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter H19
Vincristine 5978 Drug interaction    RC00000023
Etoposide 36462 Drug interaction    RC00000025
Doxorubicin 31703 Drug interaction    RC00000024
Verapamil 2520 Drug interaction    RC00000022
Resource Symbol Drug Name PubChem ID
RNAactDrug H19
6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide       9956222
Benzamide, N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-       9952773
Tivozanib       9911830
5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide       9903786
2-(4-(Benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine       9858940
6-Benzylthioinosine       95263
Benzethonium chloride       8478
Phenformin       8249
Daporinad       6914657
2-Amino-6-methoxypurine       65275
AICA ribonucleotide       65110
Tanespimycin       6505803
Ispinesib mesylate       6450816
Axitinib       6450551
Pelitinib       6445562
Phylanthoside       6436218
Cytarabine       6253
Gemcitabine       60750
Topotecan       60700
3-(2-Phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)phenol;hydrochloride       57399804
Phyllanthastatin 1       5477587
Mito-tempol       54613387
Rubremetinium chloride       5351504
N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide       53340664
Palbociclib       5330286
N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[(E)-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)ethenyl]-4-methylbenzamide       53302361
Bosutinib       5328940
Bis(2-hydroxy-1-naphthyl) disulfide       521106
Alsterpaullone       5005498
Pentamidine       4735
2-[(4s)-6-(4-Chlorophenyl)-8-Methoxy-1-Methyl-4h-[1,2,4]triazolo[4,3-A][1,4]benzodiazepin-4-Yl]-N-Ethylacetamide       46943432
3-(4-(4-(2-(3-((Dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea       46885626
N-(2,2,2-Trifluoroethyl)-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzenesulfonamide       447912
Okadaic acid       446512
1-(6,7-Dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine       44551660
Tretinoin       444795
4-[1-(4-Aminomethyl-phenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-furazan-3-ylamine       44397453
Cyclamin       441916
Foretinib       42642645
2-Chloro-3-(3-(N-morpholino)propylamino)-naphthazarine       379081
5-Fluorouracil       3385
Cetalkonium chloride       31202
Tamoxifen       2733526
[5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol       25262965
2-(4-Methyl-1,4-diazepan-1-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxamide       25257557
Cabozantinib       25102847
Ponatinib       24826799
10-(6'-Ubiquinolyl)decyltriphenylphosphonium       24783759
Vincaleukoblastine       241903
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide       24180719
Aristolochic acid       2236
6-Chloro-2-methoxy-9-[(5-piperidinopentyl)amino]acridine       219600
Nutlin-3       216345
8-Amino-5-methyl-6-phenylphenanthridin-5-ium bromide       21144180
Kinetin riboside       20345
Gsk-690693       16725726
Fedratinib       16722836
Mercury, (acetyloxy)(pentamethylphenyl)-       16683786
N-[5-[5-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-pyridin-4-ylfuran-3-yl]-2,3-dihydroinden-1-ylidene]hydroxylamine;hydrochloride       136207967
(Z)-3-((3-((Dimethylamino)methyl)phenylamino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide       135659062
N,N-Dimethyl-2-[4-[4-(1-nitroso-2,3-dihydroinden-5-ylidene)-5-(1H-pyridin-4-ylidene)-1H-imidazol-2-yl]phenoxy]ethanamine       135564599
Pac-1       135421197
Osi-027       135398516
Akt inhibitor VIII       135398501
BAY 61-3606 dihydrochloride       11784504
N-[3-[[5-Bromo-4-[[2-(1H-imidazol-5-YL)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide       11754511
Trametinib       11707110
4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine       11647372
(S)-N-((S)-1-Cyclohexyl-2-oxo-2-((3aR,7aS)-6-phenethyloctahydro-1H-pyrrolo[2,3-c]pyridin-1-yl)ethyl)-2-(methylamino)propanamide       11503417
Pararosaniline hydrochloride       11292
(S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide       11152667
Setoglaucine       107404
Dequalinium chloride       10649
VX-702       10341154
Masitinib       10074640
PDK1 inhibitor AR-12       10027278
1,4-dimethoxy-7-azaisoindole[2,1-a]quinoxalin-6(5h)-one       -
;4-fluoro-N-(3-(4-(6-(4-hydroxyphenyl)imidazo[2,1-b]thia...       -
5,6-ethylenediquino[3,2-b       -
Basic Fuchsin       -
benzo[b]naphtho[2,3-d]furan-6,11-dione, 4-chloro-3-hydroxy       -
Cisplatin       -
gamitrinib-g4       -
Genentech Cpd 10       -
gramicidin       -
g-tpp       -
KIN001-244       -
KIN001-260       -
MPS-1-IN-1       -
naphtho[2,1-b]quinolizinium, 5-chloro-7-methyl- perchlorate       -
naphtho[2,3-b]furan-4,9-dione, 2-bromo-       -
NPK76-II-72-1       -
Nutlin-3a (-)       -
pararosaniline pamoate       -
protein toxin c 10 - mw approx. 6700       -
rhodium dimer       -
riboprine(usan)       -
TL-1-85       -
TL-2-105       -
XMD13-2       -

Interaction Network (The top 100 interactions):


Interactor1: kshv-miR-K12-5-5p
Interactor2: H19

Evidence Support:


Prediction-Evidence miRanda
Support Database HumanViCe

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