Basic Information:

  VIRBase ID:  

VHID00486419

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-1-3p:  MIMAT0015214          PRPF38A:  NM_032864     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-1-3p	PRPF38A
miRBase Accession/Entrez ID	MIMAT0015214	84950
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	Prp38//PRP38A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PRPF38A	chr1:52875099(+) A-I      intronic chr1:52878528(+) A-I      intronic chr1:52871725(+) A-I      intronic chr1:52875063(+) A-I      intronic chr1:52875076(+) A-I      intronic chr1:52871790(+) A-I      intronic chr1:52875058(+) A-I      intronic chr1:52875084(+) A-I      intronic chr1:52878567(+) A-I      intronic chr1:52876310(+) A-I      intronic chr1:52876291(+) A-I      intronic chr1:52876275(+) A-I      intronic chr1:52876273(+) A-I      intronic chr1:52875923(+) A-I      intronic chr1:52875886(+) A-I      intronic chr1:52875269(+) A-I      intronic chr1:52875237(+) A-I      intronic chr1:52873640(+) A-I      intronic chr1:52873464(+) A-I      intronic chr1:52873466(+) A-I      intronic chr1:52873542(+) A-I      intronic chr1:52873549(+) A-I      intronic chr1:52873551(+) A-I      intronic chr1:52873552(+) A-I      intronic chr1:52871761(+) A-I      intronic chr1:52873568(+) A-I      intronic chr1:52873580(+) A-I      intronic chr1:52871899(+) A-I      intronic chr1:52871944(+) A-I      intronic chr1:52871954(+) A-I      intronic chr1:52871740(+) A-I      intronic chr1:52873639(+) A-I      intronic chr1:52873463(+) A-I      intronic chr1:52875121(+) A-I      intronic chr1:52873473(+) A-I      intronic chr1:52872950(+) A-I      intronic chr1:52878553(+) A-I      intronic chr1:52875176(+) A-I      intronic chr1:52875087(+) A-I      intronic chr1:52873774(+) A-I      intronic chr1:52875162(+) A-I      intronic chr1:52876448(+) A-I      intronic chr1:52875204(+) A-I      intronic chr1:52871760(+) A-I      intronic chr1:52873472(+) A-I      intronic chr1:52875163(+) A-I      intronic chr1:52875854(+) A-I      intronic chr1:52875019(+) A-I      intronic chr1:52875006(+) A-I      intronic chr1:52875919(+) A-I      intronic chr1:52875021(+) A-I      intronic chr1:52876402(+) A-I      intronic chr1:52872856(+) A-I      intronic chr1:52875136(+) A-I      intronic chr1:52879253(+) A-I      intronic chr1:52872896(+) A-I      intronic chr1:52879193(+) A-I      intronic chr1:52875073(+) A-I      intronic chr1:52879102(+) A-I      intronic chr1:52871938(+) A-I      intronic chr1:52873338(+) A-I      intronic chr1:52873518(+) A-I      intronic chr1:52875924(+) A-I      intronic chr1:52876357(+) A-I      intronic chr1:52879194(+) A-I      intronic chr1:52873562(+) A-I      intronic chr1:52876354(+) A-I      intronic chr1:52871741(+) A-I      intronic chr1:52875195(+) A-I      intronic chr1:52875122(+) A-I      intronic chr1:52873337(+) A-I      intronic chr1:52878554(+) A-I      intronic chr1:52876303(+) A-I      intronic chr1:52873331(+) A-I      intronic chr1:52876248(+) A-I      intronic chr1:52875895(+) A-I      intronic chr1:52876267(+) A-I      intronic chr1:52875107(+) A-I      intronic chr1:52873608(+) A-I      intronic chr1:52875096(+) A-I      intronic chr1:52876361(+) A-I      intronic chr1:52873544(+) A-I      intronic chr1:52875172(+) A-I      intronic chr1:52879142(+) A-I      intronic chr1:52872770(+) A-I      intronic chr1:52879161(+) A-I      intronic chr1:52873494(+) A-I      intronic chr1:52875232(+) A-I      intronic chr1:52875168(+) A-I      intronic chr1:52875041(+) A-I      intronic chr1:52871686(+) A-I      intronic chr1:52875956(+) A-I      intronic chr1:52876457(+) A-I      intronic chr1:52876278(+) A-I      intronic chr1:52872932(+) A-I      intronic chr1:52876274(+) A-I      intronic chr1:52873605(+) A-I      intronic chr1:52873565(+) A-I      intronic chr1:52871778(+) A-I      intronic chr1:52876243(+) A-I      intronic chr1:52876205(+) A-I      intronic chr1:52876313(+) A-I      intronic chr1:52876383(+) A-I      intronic chr1:52875270(+) A-I      intronic chr1:52873383(+) A-I      intronic chr1:52875123(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PRPF38A	chr1:52875019(+) A-I intron -    22327324 chr1:52875021(+) A-I intron -    22327324 chr1:52875041(+) A-I intron -    22327324 chr1:52875162(+) A-I intron -    22327324 chr1:52875122(+) A-I intron -    21960545 chr1:52871741(+) A-G intron -    22484847 chr1:52871778(+) A-G intron -    22484847 chr1:52872770(+) A-G intron -    22484847 chr1:52873494(+) A-G intron -    22484847 chr1:52873565(+) A-G intron -    22484847 chr1:52873605(+) A-G intron -    22484847 chr1:52873608(+) A-G intron -    22484847 chr1:52873774(+) A-G intron -    22484847 chr1:52875019(+) A-G intron -    22484847 chr1:52875021(+) A-G intron -    22484847 chr1:52875041(+) A-G intron -    22484847 chr1:52875096(+) A-G intron -    22484847 chr1:52875107(+) A-G intron -    22484847 chr1:52875121(+) A-G intron -    22484847 chr1:52875122(+) A-G intron -    22484847 chr1:52875123(+) A-G intron -    22484847 chr1:52875136(+) A-G intron -    22484847 chr1:52875162(+) A-G intron -    22484847 chr1:52875163(+) A-G intron -    22484847 chr1:52875168(+) A-G intron -    22484847 chr1:52875172(+) A-G intron -    22484847 chr1:52875895(+) A-G intron -    22484847 chr1:52875919(+) A-G intron -    22484847 chr1:52875924(+) A-G intron -    22484847 chr1:52876205(+) A-G intron -    22484847 chr1:52876243(+) A-G intron -    22484847 chr1:52876248(+) A-G intron -    22484847 chr1:52876267(+) A-G intron -    22484847 chr1:52876278(+) A-G intron -    22484847 chr1:52876303(+) A-G intron -    22484847 chr1:52876313(+) A-G intron -    22484847 chr1:52876354(+) A-G intron -    22484847 chr1:52876357(+) A-G intron -    22484847 chr1:52876402(+) A-G intron -    22484847 chr1:52878553(+) A-G intron -    22484847 chr1:52878554(+) A-G intron -    22484847 chr1:52879102(+) A-G intron -    22484847 chr1:52879142(+) A-G intron -    22484847 chr1:52879161(+) A-G intron -    22484847 chr1:52879193(+) A-G intron -    22484847 chr1:52879194(+) A-G intron -    22484847 chr1:52879253(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PRPF38A	chr1:52870323-52870324(+) m6A 5'UTR//exon       24284625//24981863 chr1:52870365-52870366(+) m6A 5'UTR//exon       24284625//24981863 chr1:52878246-52878247(+) m6A CDS//exon       27773535 chr1:52879596-52879597(+) m6A CDS//exon       27773535 chr1:52879602-52879603(+) m6A CDS//exon       - chr1:52881028-52881029(+) m6A CDS//exon       24284625//25456834//24981863//27773535 chr1:52882365-52882366(+) m6A 3'UTR//exon       24284625//25456834//24981863//27773535//22608085 chr1:52882582-52882583(+) m6A 3'UTR//exon       27773535 chr1:52883198-52883199(+) m6A 3'UTR       24981863 chr1:52883279-52883280(+) m6A 3'UTR       24981863//27773535 chr1:52883300-52883301(+) m6A 3'UTR       24981863//27773535 chr1:52883328-52883329(+) m6A 3'UTR       24981863//27773535 chr1:52883398-52883399(+) m6A 3'UTR       27773535//22608085 chr1:52883441-52883442(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr1:52883489-52883490(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr1:52883512-52883513(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr1:52883577-52883578(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr1:52883595-52883596(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr1:52883713-52883714(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr1:52883722-52883723(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr1:52883780-52883781(+) m6A 3'UTR       24981863//22608085 chr1:52883818-52883819(+) m6A 3'UTR       22608085 chr1:52885242-52885243(+) m6A 3'UTR       24981863//27773535//22608085 chr1:52885249-52885250(+) m6A 3'UTR       24981863//27773535//22608085 chr1:52885335-52885336(+) m6A 3'UTR       24981863//27773535//22608085 chr1:52885343-52885344(+) m6A 3'UTR       24981863//27773535//22608085 chr1:52885350-52885351(+) m6A 3'UTR       24981863//27773535//22608085 chr1:52885700-52885701(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PRPF38A	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-1-3p
Interactor2: PRPF38A

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg