Basic Information:

  VIRBase ID:  

VHID00478929

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-10a-5p:  MIMAT0015212          TP73:  NM_001204191     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-10a-5p	TP73
miRBase Accession/Entrez ID	MIMAT0015212	7161
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	P73

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TP73	chr1:3582355(+) A-I      intronic chr1:3576377(+) A-I      intronic chr1:3618148(+) A-I      intronic chr1:3618138(+) A-I      intronic chr1:3582312(+) A-I      intronic chr1:3582243(+) A-I      intronic chr1:3578194(+) A-I      intronic chr1:3578179(+) A-I      intronic chr1:3578032(+) A-I      intronic chr1:3576466(+) A-I      intronic chr1:3576444(+) A-I      intronic chr1:3576427(+) A-I      intronic chr1:3576294(+) A-I      intronic chr1:3578250(+) A-I      intronic chr1:3582319(+) A-I      intronic chr1:3641490(+) A-I      intronic chr1:3582575(+) A-I      intronic chr1:3576433(+) A-I      intronic chr1:3576424(+) A-I      intronic chr1:3576379(+) A-I      intronic chr1:3582280(+) A-I      intronic chr1:3576346(+) A-I      intronic chr1:3578605(+) A-I      intronic chr1:3578170(+) A-I      intronic chr1:3578056(+) A-I      intronic chr1:3576345(+) A-I      intronic chr1:3578117(+) A-I      intronic chr1:3652338(+) A-I      3'UTR chr1:3576512(+) A-I      intronic chr1:3641462(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TP73	chr1:3571874(+) T-C intron -    22484847 chr1:3641490(+) A-G intron -    22484847 chr1:3645570(+) G-C intron -    22484847 chr1:3652338(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TP73	chr1:3614711-3614712(+) m6A 5'UTR//exon//intron       - chr1:3624143-3624144(+) m6A CDS//exon       - chr1:3624294-3624295(+) m6A CDS//exon       24284625 chr1:3638604-3638605(+) m6A CDS//exon       - chr1:3638626-3638627(+) m6A CDS//exon       - chr1:3644764-3644765(+) m6A CDS//exon       - chr1:3648052-3648053(+) m6A CDS//exon//intron       - chr1:3648106-3648107(+) m6A CDS//exon//intron       - chr1:3649371-3649372(+) m6A 3'UTR//CDS//exon       - chr1:3649459-3649460(+) m6A 3'UTR//CDS//exon       24284625 chr1:3649563-3649564(+) m6A 3'UTR//CDS//exon       25456834 chr1:3649681-3649682(+) m6A 3'UTR//exon       24284625//25456834//22608085 chr1:3649719-3649720(+) m6A 3'UTR//exon       24284625//25456834//22608085 chr1:3649737-3649738(+) m6A 3'UTR//exon       24284625//25456834//22608085 chr1:3649832-3649833(+) m6A 3'UTR//exon       24284625//24209618//25456834//22608085 chr1:3649853-3649854(+) m6A 3'UTR//exon       24284625//24209618//25456834//22608085 chr1:3649954-3649955(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr1:3649994-3649995(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr1:3650053-3650054(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr1:3650124-3650125(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr1:3650184-3650185(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr1:3650198-3650199(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr1:3650205-3650206(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr1:3650241-3650242(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr1:3650295-3650296(+) m6A 3'UTR       24284625//24209618//25456834//24981863 chr1:3650391-3650392(+) m6A 3'UTR       24284625//25456834 chr1:3650409-3650410(+) m6A 3'UTR       - chr1:3650427-3650428(+) m6A 3'UTR       - chr1:3652296-3652297(+) m6A 3'UTR       27773536 chr1:3652390-3652391(+) m6A 3'UTR       - chr1:3652508-3652509(+) m6A 3'UTR       27773535 chr1:3652532-3652533(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	TP73	Chromatin K562 cells     - Exosome Blood     - Nucleus K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-10a-5p
Interactor2: TP73

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg