Basic Information:

  VIRBase ID:  

VHID00478201

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-10a-5p:  MIMAT0015212          RUNX2:  NR_103532     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-10a-5p	RUNX2
miRBase Accession/Entrez ID	MIMAT0015212	860
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	AML3//CBF-alpha-1//CBFA1//CCD//CCD1//CLCD//OSF-2//OSF2//PEA2aA//PEBP2aA

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RUNX2	chr6:45348414(+) A-I      intronic chr6:45410988(+) A-I      intronic chr6:45347354(+) A-I      intronic chr6:45433512(+) A-I      intronic chr6:45411010(+) A-I      intronic chr6:45517661(+) A-I      3'UTR chr6:45503194(+) A-I      intronic chr6:45491288(+) A-I      intronic chr6:45493556(+) A-I      intronic chr6:45491282(+) A-I      intronic chr6:45491416(+) A-I      intronic chr6:45347472(+) A-I      intronic chr6:45493470(+) A-I      intronic chr6:45491143(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RUNX2	chr6:45424493(+) A-I intron -    21960545 chr6:45347472(+) A-G intron -    22484847 chr6:45491129(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RUNX2	chr6:45296079-45296080(+) m6A 5'UTR//exon       - chr6:45296090-45296091(+) m6A 5'UTR//exon       - chr6:45296108-45296109(+) m6A 5'UTR//exon       - chr6:45296123-45296124(+) m6A 5'UTR//exon       - chr6:45296184-45296185(+) m6A 5'UTR//exon       - chr6:45389885-45389886(+) m6A 5'UTR//intron       - chr6:45389893-45389894(+) m6A 5'UTR//intron       - chr6:45389915-45389916(+) m6A 5'UTR//intron       25456834 chr6:45389966-45389967(+) m6A 5'UTR//intron       25456834//24981863 chr6:45389985-45389986(+) m6A 5'UTR//intron       24284625//25456834//24981863 chr6:45390013-45390014(+) m6A 5'UTR//intron       24284625//24209618//25456834//24981863 chr6:45390060-45390061(+) m6A 5'UTR//intron       24284625//24209618//24981863//27371828 chr6:45390126-45390127(+) m6A 5'UTR//intron       24284625//24209618//24981863//27371828 chr6:45390144-45390145(+) m6A 5'UTR//intron       24284625//24209618//24981863//27371828 chr6:45390171-45390172(+) m6A 5'UTR//intron       24209618 chr6:45390606-45390607(+) m6A CDS//intron       - chr6:45390673-45390674(+) m6A CDS//intron       - chr6:45405771-45405772(+) m6A 3'UTR//CDS       - chr6:45405780-45405781(+) m6A 3'UTR//CDS       - chr6:45459684-45459685(+) m6A 3'UTR//CDS//intron       - chr6:45459705-45459706(+) m6A 3'UTR//CDS//intron       - chr6:45459785-45459786(+) m6A 3'UTR//CDS//intron       - chr6:45459803-45459804(+) m6A 3'UTR//CDS//intron       - chr6:45459834-45459835(+) m6A 3'UTR//CDS//intron       - chr6:45514573-45514574(+) m6A 3'UTR//CDS//intron       - chr6:45514590-45514591(+) m6A 3'UTR//CDS//intron       - chr6:45514780-45514781(+) m6A 3'UTR//CDS//intron       24284625//24209618 chr6:45514790-45514791(+) m6A 3'UTR//CDS//intron       24209618 chr6:45515247-45515248(+) m6A 3'UTR//intron       24209618//24981863 chr6:45515303-45515304(+) m6A 3'UTR//intron       24209618//24981863 chr6:45515388-45515389(+) m6A 3'UTR//intron       24209618//24981863 chr6:45515441-45515442(+) m6A 3'UTR//intron       24209618//25456834//24981863 chr6:45515474-45515475(+) m6A 3'UTR//intron       24209618//25456834//24981863 chr6:45515491-45515492(+) m6A 3'UTR//intron       24209618//25456834//24981863 chr6:45515503-45515504(+) m6A 3'UTR//intron       24209618//25456834//24981863 chr6:45515526-45515527(+) m6A 3'UTR//intron       24209618//25456834//24981863 chr6:45515597-45515598(+) m6A 3'UTR//intron       24209618//24981863 chr6:45515620-45515621(+) m6A 3'UTR//intron       24209618//24981863 chr6:45515741-45515742(+) m6A 3'UTR//intron       24209618 chr6:45515766-45515767(+) m6A 3'UTR//intron       24209618 chr6:45516898-45516899(+) m6A 3'UTR//intron       - chr6:45517017-45517018(+) m6A 3'UTR//intron       - chr6:45517053-45517054(+) m6A 3'UTR//intron       - chr6:45630872-45630873(+) m6A 3'UTR//CDS       24209618 chr6:45631334-45631335(+) m6A 3'UTR//CDS       24209618//25456834 chr6:45631354-45631355(+) m6A 3'UTR//CDS       24209618//25456834 chr6:45631373-45631374(+) m6A 3'UTR//CDS       24209618//25456834 chr6:45631398-45631399(+) m6A 3'UTR//CDS       24209618//25456834 chr6:45631616-45631617(+) m6A 3'UTR       24209618 chr6:45631774-45631775(+) m6A 3'UTR       24209618

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	RUNX2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-10a-5p
Interactor2: RUNX2

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg