Basic Information:

  VIRBase ID:  

VHID00476773

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-12-5p:  MIMAT0003712          TSEN15:  NM_001300766     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-12-5p	TSEN15
miRBase Accession/Entrez ID	MIMAT0003712	116461
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	C1orf19//PCH2F//sen15

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TSEN15	chr1:184036982(+) A-I      intronic chr1:184036780(+) A-I      intronic chr1:184028968(+) A-I      intronic chr1:184035669(+) A-I      intronic chr1:184035802(+) A-I      intronic chr1:184028831(+) A-I      intronic chr1:184036906(+) A-I      intronic chr1:184035679(+) A-I      intronic chr1:184035768(+) A-I      intronic chr1:184028940(+) A-I      intronic chr1:184036964(+) A-I      intronic chr1:184036959(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TSEN15	chr1:184036964(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TSEN15	chr1:184020813-184020814(+) m6A 5'UTR       24981863 chr1:184043065-184043066(+) m6A 3'UTR       27773535 chr1:184043127-184043128(+) m6A 3'UTR       27773535 chr1:184043205-184043206(+) m6A 3'UTR       24981863//27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	kshv-miR-K12-12-5p	Exosome Primary dendritic cells     21505438
	TSEN15	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-12-5p
Interactor2: TSEN15

Evidence Support:

Prediction-Evidence	miRanda//PITA
Support Database	VmiReg