Basic Information:

  VIRBase ID:  

VHID00474633

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-12-5p:  MIMAT0003712          KLHL20:  NM_014458     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-12-5p	KLHL20
miRBase Accession/Entrez ID	MIMAT0003712	27252
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	KHLHX//KLEIP//KLHLX

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	KLHL20	chr1:173723573(+) A-I      intronic chr1:173723563(+) A-I      intronic chr1:173704464(+) A-I      intronic chr1:173691326(+) A-I      intronic chr1:173691300(+) A-I      intronic chr1:173723567(+) A-I      intronic chr1:173691922(+) A-I      intronic chr1:173691325(+) A-I      intronic chr1:173748593(+) A-I      intronic chr1:173691319(+) A-I      intronic chr1:173750503(+) A-I      intronic chr1:173702288(+) A-I      intronic chr1:173748651(+) A-I      intronic chr1:173689202(+) A-I      intronic chr1:173702325(+) A-I      intronic chr1:173723616(+) A-I      intronic chr1:173723668(+) A-I      intronic chr1:173723680(+) A-I      intronic chr1:173724278(+) A-I      intronic chr1:173691499(+) A-I      intronic chr1:173689186(+) A-I      intronic chr1:173748724(+) A-I      intronic chr1:173724291(+) A-I      intronic chr1:173724302(+) A-I      intronic chr1:173688497(+) A-I      intronic chr1:173750534(+) A-I      intronic chr1:173705212(+) A-I      intronic chr1:173749800(+) A-I      intronic chr1:173724315(+) A-I      intronic chr1:173687276(+) A-I      intronic chr1:173724339(+) A-I      intronic chr1:173724355(+) A-I      intronic chr1:173724359(+) A-I      intronic chr1:173688496(+) A-I      intronic chr1:173724381(+) A-I      intronic chr1:173724400(+) A-I      intronic chr1:173750787(+) A-I      intronic chr1:173727272(+) A-I      intronic chr1:173691610(+) A-I      intronic chr1:173749809(+) A-I      intronic chr1:173749812(+) A-I      intronic chr1:173742139(+) A-I      intronic chr1:173691848(+) A-I      intronic chr1:173687250(+) A-I      intronic chr1:173691551(+) A-I      intronic chr1:173691909(+) A-I      intronic chr1:173702300(+) A-I      intronic chr1:173691928(+) A-I      intronic chr1:173750547(+) A-I      intronic chr1:173691932(+) A-I      intronic chr1:173742159(+) A-I      intronic chr1:173705231(+) A-I      intronic chr1:173691522(+) A-I      intronic chr1:173723582(+) A-I      intronic chr1:173691933(+) A-I      intronic chr1:173692090(+) A-I      intronic chr1:173742206(+) A-I      intronic chr1:173750540(+) A-I      intronic chr1:173687599(+) A-I      intronic chr1:173701205(+) A-I      intronic chr1:173687476(+) A-I      intronic chr1:173687287(+) A-I      intronic chr1:173687469(+) A-I      intronic chr1:173701207(+) A-I      intronic chr1:173742255(+) A-I      intronic chr1:173701215(+) A-I      intronic chr1:173687327(+) A-I      intronic chr1:173749830(+) A-I      intronic chr1:173701225(+) A-I      intronic chr1:173701261(+) A-I      intronic chr1:173702284(+) A-I      intronic chr1:173687329(+) A-I      intronic chr1:173749794(+) A-I      intronic chr1:173749678(+) A-I      intronic chr1:173742346(+) A-I      intronic chr1:173742185(+) A-I      intronic chr1:173740637(+) A-I      intronic chr1:173705155(+) A-I      intronic chr1:173742133(+) A-I      intronic chr1:173725536(+) A-I      intronic chr1:173735792(+) A-I      intronic chr1:173749854(+) A-I      intronic chr1:173702276(+) A-I      intronic chr1:173723713(+) A-I      intronic chr1:173724449(+) A-I      intronic chr1:173740800(+) A-I      intronic chr1:173750676(+) A-I      intronic chr1:173691546(+) A-I      intronic chr1:173742487(+) A-I      intronic chr1:173742155(+) A-I      intronic chr1:173742243(+) A-I      intronic chr1:173687482(+) A-I      intronic chr1:173693837(+) A-I      intronic chr1:173740661(+) A-I      intronic chr1:173724459(+) A-I      intronic chr1:173691697(+) A-I      intronic chr1:173742294(+) A-I      intronic chr1:173704474(+) A-I      intronic chr1:173742246(+) A-I      intronic chr1:173702259(+) A-I      intronic chr1:173702223(+) A-I      intronic chr1:173742349(+) A-I      intronic chr1:173723462(+) A-I      intronic chr1:173742488(+) A-I      intronic chr1:173749840(+) A-I      intronic chr1:173723546(+) A-I      intronic chr1:173691609(+) A-I      intronic chr1:173749808(+) A-I      intronic chr1:173724324(+) A-I      intronic chr1:173742466(+) A-I      intronic chr1:173691608(+) A-I      intronic chr1:173744029(+) A-I      intronic chr1:173723678(+) A-I      intronic chr1:173742295(+) A-I      intronic chr1:173705835(+) A-I      intronic chr1:173723672(+) A-I      intronic chr1:173750815(+) A-I      intronic chr1:173749841(+) A-I      intronic chr1:173742493(+) A-I      intronic chr1:173724471(+) A-I      intronic chr1:173740856(+) A-I      intronic chr1:173704420(+) A-I      intronic chr1:173740859(+) A-I      intronic chr1:173749836(+) A-I      intronic chr1:173724261(+) A-I      intronic chr1:173750001(+) A-I      intronic chr1:173691246(+) A-I      intronic chr1:173740796(+) A-I      intronic chr1:173691342(+) A-I      intronic chr1:173740626(+) A-I      intronic chr1:173723547(+) A-I      intronic chr1:173691514(+) A-I      intronic chr1:173742363(+) A-I      intronic chr1:173724292(+) A-I      intronic chr1:173742371(+) A-I      intronic chr1:173750663(+) A-I      intronic chr1:173692012(+) A-I      intronic chr1:173691602(+) A-I      intronic chr1:173691607(+) A-I      intronic chr1:173725649(+) A-I      intronic chr1:173748772(+) A-I      intronic chr1:173702324(+) A-I      intronic chr1:173702285(+) A-I      intronic chr1:173702335(+) A-I      intronic chr1:173742226(+) A-I      intronic chr1:173724262(+) A-I      intronic chr1:173748570(+) A-I      intronic chr1:173740849(+) A-I      intronic chr1:173742179(+) A-I      intronic chr1:173723539(+) A-I      intronic chr1:173742229(+) A-I      intronic chr1:173749948(+) A-I      intronic chr1:173688683(+) A-I      intronic chr1:173725484(+) A-I      intronic chr1:173738820(+) A-I      intronic chr1:173742225(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	KLHL20	chr1:173691608(+) A-G intron -    22484847 chr1:173692012(+) A-G intron -    22484847 chr1:173702285(+) A-G intron -    22484847 chr1:173702324(+) A-G intron -    22484847 chr1:173704420(+) A-G intron -    22484847 chr1:173704490(+) T-C intron -    22484847 chr1:173705835(+) A-G intron -    22484847 chr1:173723462(+) A-G intron -    22484847 chr1:173723539(+) A-G intron -    22484847 chr1:173723547(+) A-G intron -    22484847 chr1:173723672(+) A-G intron -    22484847 chr1:173723678(+) A-G intron -    22484847 chr1:173724261(+) A-G intron -    22484847 chr1:173724262(+) A-G intron -    22484847 chr1:173724292(+) A-G intron -    22484847 chr1:173724324(+) A-G intron -    22484847 chr1:173738820(+) A-G intron -    22484847 chr1:173738862(+) G-T intron -    22484847 chr1:173742243(+) A-G intron -    22484847 chr1:173742295(+) A-G intron -    22484847 chr1:173742363(+) A-G intron -    22484847 chr1:173742487(+) A-G intron -    22484847 chr1:173748570(+) A-G intron -    22484847 chr1:173750001(+) A-G intron -    22484847 chr1:173750815(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	KLHL20	chr1:173684483-173684484(+) m6A exon//intron       24981863 chr1:173684496-173684497(+) m6A exon//intron       24981863 chr1:173684554-173684555(+) m6A exon//intron       24981863 chr1:173684585-173684586(+) m6A exon//intron       24981863 chr1:173684599-173684600(+) m6A exon//intron       24981863 chr1:173684669-173684670(+) m6A exon//intron       - chr1:173684733-173684734(+) m6A exon//intron       - chr1:173702876-173702877(+) m6A CDS//exon       24284625//24209618//24981863//22608085 chr1:173702913-173702914(+) m6A CDS//exon       24284625//24209618//24981863//22608085 chr1:173702923-173702924(+) m6A CDS//exon       24284625//24209618//24981863//22608085 chr1:173702970-173702971(+) m6A CDS//exon       24284625//24209618//22608085 chr1:173702987-173702988(+) m6A CDS//exon       24284625//24209618//22608085 chr1:173703146-173703147(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr1:173703165-173703166(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr1:173703245-173703246(+) m6A CDS//exon       24284625//24209618//24981863//22575960//22608085 chr1:173703316-173703317(+) m6A CDS//exon       24284625//24209618//24981863//22575960//22608085 chr1:173703396-173703397(+) m6A CDS//exon       24284625//24209618//24981863//22608085 chr1:173743558-173743559(+) m6A CDS       - chr1:173744796-173744797(+) m6A CDS       - chr1:173744825-173744826(+) m6A CDS       - chr1:173744836-173744837(+) m6A CDS       - chr1:173751330-173751331(+) m6A CDS//exon       22608085 chr1:173754385-173754386(+) m6A 3'UTR//exon       24284625//24209618//24981863//22608085 chr1:173754396-173754397(+) m6A 3'UTR//exon       24284625//24209618//24981863//22608085 chr1:173754464-173754465(+) m6A 3'UTR//exon       24284625//24209618//24981863//22608085 chr1:173754472-173754473(+) m6A 3'UTR//exon       24284625//24209618//24981863//22608085 chr1:173754626-173754627(+) m6A 3'UTR//exon       24981863//22608085 chr1:173754680-173754681(+) m6A 3'UTR       24981863//22608085 chr1:173754771-173754772(+) m6A 3'UTR       24981863//22608085 chr1:173754872-173754873(+) m6A 3'UTR       24981863//27773535//22608085 chr1:173754896-173754897(+) m6A 3'UTR       24981863//27773535//22608085 chr1:173754904-173754905(+) m6A 3'UTR       24981863//27773535//22608085 chr1:173754967-173754968(+) m6A 3'UTR       24981863//27773535 chr1:173754973-173754974(+) m6A 3'UTR       24981863 chr1:173754979-173754980(+) m6A 3'UTR       24981863 chr1:173755452-173755453(+) Y 3'UTR       26075521

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	kshv-miR-K12-12-5p	Exosome Primary dendritic cells     21505438
	KLHL20	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-12-5p
Interactor2: KLHL20

Evidence Support:

Prediction-Evidence	PITA//Rep
Support Database	RepTar//VmiReg