Basic Information:

  VIRBase ID:  

VHID00473742

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-12-5p:  MIMAT0003712          PPIF:  NM_005729     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-12-5p	PPIF
miRBase Accession/Entrez ID	MIMAT0003712	10105
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	Cyp-D//CyP-M//CYP3//CypD

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PPIF	chr10:81109644(+) A-I      intronic chr10:81110343(+) A-I      intronic chr10:81109655(+) A-I      intronic chr10:81109710(+) A-I      intronic chr10:81109666(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PPIF	chr10:81107437-81107438(+) m6A CDS//exon       24284625//27773536//22575960 chr10:81108855-81108856(+) m6A CDS//exon       24284625//22575960 chr10:81109423-81109424(+) m6A CDS//exon       24284625//22575960 chr10:81111312-81111313(+) m6A CDS//exon       24284625 chr10:81112140-81112141(+) m6A 3'UTR//CDS       24284625//22575960 chr10:81113553-81113554(+) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//22575960 chr10:81113578-81113579(+) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//22575960 chr10:81113746-81113747(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:81113758-81113759(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr10:81113822-81113823(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr10:81113891-81113892(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr10:81113949-81113950(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr10:81113969-81113970(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr10:81114039-81114040(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr10:81114098-81114099(+) m6A 3'UTR       24284625//24209618//26404942//22575960 chr10:81114120-81114121(+) m6A 3'UTR       24284625//22575960 chr10:81114240-81114241(+) m6A 3'UTR       24284625//22575960 chr10:81114248-81114249(+) m6A 3'UTR       24284625//22575960 chr10:81114274-81114275(+) m6A 3'UTR       24284625 chr10:81114474-81114475(+) m6A 3'UTR       24284625 chr10:81114627-81114628(+) m6A 3'UTR       24284625 chr10:81114780-81114781(+) m6A 3'UTR       24284625//24981863 chr10:81115057-81115058(+) m6A 3'UTR       24284625//24981863 chr10:81115073-81115074(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	kshv-miR-K12-12-5p	Exosome Primary dendritic cells     21505438
	PPIF	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-12-5p
Interactor2: PPIF

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid//Targetscan
Support Database	VmiReg