Basic Information:

  VIRBase ID:  

VHID00473263

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-12-5p:  MIMAT0003712          PEA15:  NR_123724     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-12-5p	PEA15
miRBase Accession/Entrez ID	MIMAT0003712	8682
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	HMAT1//HUMMAT1H//MAT1//MAT1H//PEA-15//PED//PED-PEA15//PED/PEA15

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PEA15	chr1:160175263-160175264(+) m6A 5'UTR       24284625//24209618//24981863 chr1:160175270-160175271(+) m6A 5'UTR       24284625//24209618//24981863 chr1:160176968-160176969(+) m6A 5'UTR//intron       24284625//24209618//24981863 chr1:160178410-160178411(+) m6A CDS//intron       24209618 chr1:160178445-160178446(+) m6A CDS//intron       24209618 chr1:160181349-160181350(+) m6A CDS//exon       24209618//24981863 chr1:160181362-160181363(+) m6A CDS//exon       24209618//24981863 chr1:160181396-160181397(+) m6A CDS//exon       24209618//24981863 chr1:160181422-160181423(+) m6A CDS//exon       24209618//24981863 chr1:160181500-160181501(+) m6A CDS//exon//intron       24981863 chr1:160182976-160182977(+) m6A CDS//exon       24981863 chr1:160183013-160183014(+) m6A CDS//exon       24981863 chr1:160183305-160183306(+) m6A 3'UTR//exon       26404942 chr1:160183630-160183631(+) m6A 3'UTR       24981863 chr1:160183726-160183727(+) m6A 3'UTR       24981863 chr1:160184159-160184160(+) m6A 3'UTR       - chr1:160184236-160184237(+) m6A 3'UTR       - chr1:160184249-160184250(+) m6A 3'UTR       - chr1:160184289-160184290(+) m6A 3'UTR       - chr1:160184417-160184418(+) m6A 3'UTR       24981863 chr1:160184543-160184544(+) m6A 3'UTR       24981863 chr1:160184568-160184569(+) m6A 3'UTR       24981863 chr1:160184595-160184596(+) m6A 3'UTR       24981863//26404942 chr1:160184604-160184605(+) m6A 3'UTR       26404942 chr1:160184644-160184645(+) m6A 3'UTR       26404942 chr1:160184900-160184901(+) m6A 3'UTR       26404942 chr1:160184984-160184985(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	kshv-miR-K12-12-5p	Exosome Primary dendritic cells     21505438
	PEA15	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-12-5p
Interactor2: PEA15

Evidence Support:

Prediction-Evidence	miRanda//PITA//RNAHybrid//Targetscan
Support Database	VmiReg