Basic Information:

  VIRBase ID:  

VHID00472497

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-12-5p:  MIMAT0003712          PPP2R5A:  NM_006243     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-12-5p	PPP2R5A
miRBase Accession/Entrez ID	MIMAT0003712	5525
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	B56A//B56alpha//PR61A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PPP2R5A	chr1:212508602(+) A-I      intronic chr1:212508631(+) A-I      intronic chr1:212508638(+) A-I      intronic chr1:212508674(+) A-I      intronic chr1:212508660(+) A-I      intronic chr1:212527915(+) A-I      intronic chr1:212527895(+) A-I      intronic chr1:212523867(+) A-I      intronic chr1:212527879(+) A-I      intronic chr1:212509655(+) A-I      intronic chr1:212515209(+) A-I      intronic chr1:212518386(+) A-I      intronic chr1:212525818(+) A-I      intronic chr1:212517501(+) A-I      intronic chr1:212527870(+) A-I      intronic chr1:212527876(+) A-I      intronic chr1:212515269(+) A-I      intronic chr1:212527922(+) A-I      intronic chr1:212508657(+) A-I      intronic chr1:212508656(+) A-I      intronic chr1:212508653(+) A-I      intronic chr1:212508642(+) A-I      intronic chr1:212515221(+) A-I      intronic chr1:212499674(+) A-I      intronic chr1:212499689(+) A-I      intronic chr1:212529255(+) A-I      intronic chr1:212499726(+) A-I      intronic chr1:212499786(+) A-I      intronic chr1:212529251(+) A-I      intronic chr1:212499788(+) A-I      intronic chr1:212529242(+) A-I      intronic chr1:212529224(+) A-I      intronic chr1:212499824(+) A-I      intronic chr1:212529222(+) A-I      intronic chr1:212501632(+) A-I      intronic chr1:212527842(+) A-I      intronic chr1:212527811(+) A-I      intronic chr1:212527771(+) A-I      intronic chr1:212527440(+) A-I      intronic chr1:212502167(+) A-I      intronic chr1:212502198(+) A-I      intronic chr1:212502207(+) A-I      intronic chr1:212503082(+) A-I      intronic chr1:212503249(+) A-I      intronic chr1:212515219(+) A-I      intronic chr1:212504236(+) A-I      intronic chr1:212504238(+) A-I      intronic chr1:212527366(+) A-I      intronic chr1:212504276(+) A-I      intronic chr1:212527360(+) A-I      intronic chr1:212525999(+) A-I      intronic chr1:212525953(+) A-I      intronic chr1:212525941(+) A-I      intronic chr1:212504295(+) A-I      intronic chr1:212525937(+) A-I      intronic chr1:212504360(+) A-I      intronic chr1:212504431(+) A-I      intronic chr1:212504451(+) A-I      intronic chr1:212504580(+) A-I      intronic chr1:212504619(+) A-I      intronic chr1:212525931(+) A-I      intronic chr1:212504620(+) A-I      intronic chr1:212499819(+) A-I      intronic chr1:212504713(+) A-I      intronic chr1:212504779(+) A-I      intronic chr1:212506377(+) A-I      intronic chr1:212506386(+) A-I      intronic chr1:212506428(+) A-I      intronic chr1:212506507(+) A-I      intronic chr1:212508621(+) A-I      intronic chr1:212525918(+) A-I      intronic chr1:212525917(+) A-I      intronic chr1:212525866(+) A-I      intronic chr1:212508658(+) A-I      intronic chr1:212508670(+) A-I      intronic chr1:212508678(+) A-I      intronic chr1:212508697(+) A-I      intronic chr1:212499891(+) A-I      intronic chr1:212508703(+) A-I      intronic chr1:212509709(+) A-I      intronic chr1:212525835(+) A-I      intronic chr1:212525632(+) A-I      intronic chr1:212525571(+) A-I      intronic chr1:212525562(+) A-I      intronic chr1:212525531(+) A-I      intronic chr1:212525507(+) A-I      intronic chr1:212524996(+) A-I      intronic chr1:212524945(+) A-I      intronic chr1:212509737(+) A-I      intronic chr1:212511914(+) A-I      intronic chr1:212511998(+) A-I      intronic chr1:212512014(+) A-I      intronic chr1:212512613(+) A-I      intronic chr1:212524920(+) A-I      intronic chr1:212512624(+) A-I      intronic chr1:212524891(+) A-I      intronic chr1:212512645(+) A-I      intronic chr1:212513378(+) A-I      intronic chr1:212524875(+) A-I      intronic chr1:212515149(+) A-I      intronic chr1:212515193(+) A-I      intronic chr1:212524846(+) A-I      intronic chr1:212477717(+) A-I      intronic chr1:212515301(+) A-I      intronic chr1:212531194(+) A-I      intronic chr1:212515316(+) A-I      intronic chr1:212523905(+) A-I      intronic chr1:212515320(+) A-I      intronic chr1:212523897(+) A-I      intronic chr1:212517477(+) A-I      intronic chr1:212477706(+) A-I      intronic chr1:212477707(+) A-I      intronic chr1:212477740(+) A-I      intronic chr1:212477797(+) A-I      intronic chr1:212517533(+) A-I      intronic chr1:212477811(+) A-I      intronic chr1:212518299(+) A-I      intronic chr1:212518319(+) A-I      intronic chr1:212531110(+) A-I      intronic chr1:212530995(+) A-I      intronic chr1:212529301(+) A-I      intronic chr1:212518330(+) A-I      intronic chr1:212531224(+) A-I      intronic chr1:212531218(+) A-I      intronic chr1:212478106(+) A-I      intronic chr1:212523740(+) A-I      intronic chr1:212531195(+) A-I      intronic chr1:212518341(+) A-I      intronic chr1:212478139(+) A-I      intronic chr1:212529260(+) A-I      intronic chr1:212478275(+) A-I      intronic chr1:212519367(+) A-I      intronic chr1:212478284(+) A-I      intronic chr1:212519375(+) A-I      intronic chr1:212519448(+) A-I      intronic chr1:212481892(+) A-I      intronic chr1:212498194(+) A-I      intronic chr1:212513394(+) A-I      intronic chr1:212525815(+) A-I      intronic chr1:212519473(+) A-I      intronic chr1:212511864(+) A-I      intronic chr1:212488107(+) A-I      intronic chr1:212527765(+) A-I      intronic chr1:212513403(+) A-I      intronic chr1:212524806(+) A-I      intronic chr1:212525891(+) A-I      intronic chr1:212517505(+) A-I      intronic chr1:212524366(+) A-I      intronic chr1:212477637(+) A-I      intronic chr1:212531095(+) A-I      intronic chr1:212518470(+) A-I      intronic chr1:212518360(+) A-I      intronic chr1:212511943(+) A-I      intronic chr1:212504390(+) A-I      intronic chr1:212511968(+) A-I      intronic chr1:212488105(+) A-I      intronic chr1:212518416(+) A-I      intronic chr1:212478130(+) A-I      intronic chr1:212517478(+) A-I      intronic chr1:212515218(+) A-I      intronic chr1:212524935(+) A-I      intronic chr1:212518307(+) A-I      intronic chr1:212524929(+) A-I      intronic chr1:212474404(+) A-I      intronic chr1:212498086(+) A-I      intronic chr1:212523921(+) A-I      intronic chr1:212500937(+) A-I      intronic chr1:212504572(+) A-I      intronic chr1:212525385(+) A-I      intronic chr1:212529286(+) A-I      intronic chr1:212530998(+) A-I      intronic chr1:212477692(+) A-I      intronic chr1:212525440(+) A-I      intronic chr1:212518432(+) A-I      intronic chr1:212519524(+) A-I      intronic chr1:212526066(+) A-I      intronic chr1:212523916(+) A-I      intronic chr1:212525599(+) A-I      intronic chr1:212524992(+) A-I      intronic chr1:212524401(+) A-I      intronic chr1:212526943(+) A-I      intronic chr1:212523735(+) A-I      intronic chr1:212525500(+) A-I      intronic chr1:212508607(+) A-I      intronic chr1:212523741(+) A-I      intronic chr1:212508560(+) A-I      intronic chr1:212525387(+) A-I      intronic chr1:212478508(+) A-I      intronic chr1:212509638(+) A-I      intronic chr1:212518248(+) A-I      intronic chr1:212477617(+) A-I      intronic chr1:212519509(+) A-I      intronic chr1:212497294(+) A-I      intronic chr1:212480200(+) A-I      intronic chr1:212509619(+) A-I      intronic chr1:212504603(+) A-I      intronic chr1:212525823(+) A-I      intronic chr1:212517413(+) A-I      intronic chr1:212524395(+) A-I      intronic chr1:212527766(+) A-I      intronic chr1:212524936(+) A-I      intronic chr1:212504602(+) A-I      intronic chr1:212478222(+) A-I      intronic chr1:212525933(+) A-I      intronic chr1:212478216(+) A-I      intronic chr1:212528026(+) A-I      intronic chr1:212525568(+) A-I      intronic chr1:212504645(+) A-I      intronic chr1:212525505(+) A-I      intronic chr1:212523746(+) A-I      intronic chr1:212504395(+) A-I      intronic chr1:212524793(+) A-I      intronic chr1:212512620(+) A-I      intronic chr1:212478136(+) A-I      intronic chr1:212478214(+) A-I      intronic chr1:212524854(+) A-I      intronic chr1:212527272(+) A-I      intronic chr1:212525850(+) A-I      intronic chr1:212525591(+) A-I      intronic chr1:212518296(+) A-I      intronic chr1:212508647(+) A-I      intronic chr1:212509692(+) A-I      intronic chr1:212525831(+) A-I      intronic chr1:212517496(+) A-I      intronic chr1:212525554(+) A-I      intronic chr1:212527905(+) A-I      intronic chr1:212517499(+) A-I      intronic chr1:212518396(+) A-I      intronic chr1:212511867(+) A-I      intronic chr1:212511919(+) A-I      intronic chr1:212508662(+) A-I      intronic chr1:212524878(+) A-I      intronic chr1:212499680(+) A-I      intronic chr1:212525633(+) A-I      intronic chr1:212525600(+) A-I      intronic chr1:212518392(+) A-I      intronic chr1:212504460(+) A-I      intronic chr1:212525885(+) A-I      intronic chr1:212511885(+) A-I      intronic chr1:212523889(+) A-I      intronic chr1:212527264(+) A-I      intronic chr1:212527951(+) A-I      intronic chr1:212513415(+) A-I      intronic chr1:212511986(+) A-I      intronic chr1:212503092(+) A-I      intronic chr1:212525645(+) A-I      intronic chr1:212525909(+) A-I      intronic chr1:212511982(+) A-I      intronic chr1:212531243(+) A-I      intronic chr1:212526054(+) A-I      intronic chr1:212525978(+) A-I      intronic chr1:212506343(+) A-I      intronic chr1:212498154(+) A-I      intronic chr1:212523908(+) A-I      intronic chr1:212477635(+) A-I      intronic chr1:212527271(+) A-I      intronic chr1:212525639(+) A-I      intronic chr1:212524013(+) A-I      intronic chr1:212515227(+) A-I      intronic chr1:212512665(+) A-I      intronic chr1:212504389(+) A-I      intronic chr1:212523857(+) A-I      intronic chr1:212529209(+) A-I      intronic chr1:212512619(+) A-I      intronic chr1:212504363(+) A-I      intronic chr1:212477638(+) A-I      intronic chr1:212513421(+) A-I      intronic chr1:212525921(+) A-I      intronic chr1:212524365(+) A-I      intronic chr1:212513435(+) A-I      intronic chr1:212478022(+) A-I      intronic chr1:212531160(+) A-I      intronic chr1:212529284(+) A-I      intronic chr1:212523865(+) A-I      intronic chr1:212529356(+) A-I      intronic chr1:212527286(+) A-I      intronic chr1:212517414(+) A-I      intronic chr1:212477762(+) A-I      intronic chr1:212529287(+) A-I      intronic chr1:212527862(+) A-I      intronic chr1:212479234(+) A-I      intronic chr1:212499681(+) A-I      intronic chr1:212504636(+) A-I      intronic chr1:212517394(+) A-I      intronic chr1:212519413(+) A-I      intronic chr1:212517407(+) A-I      intronic chr1:212491207(+) A-I      intronic chr1:212524870(+) A-I      intronic chr1:212504642(+) A-I      intronic chr1:212523327(+) A-I      intronic chr1:212461538(+) A-I      intronic chr1:212518320(+) A-I      intronic chr1:212478585(+) A-I      intronic chr1:212477771(+) A-I      intronic chr1:212509718(+) A-I      intronic chr1:212503089(+) A-I      intronic chr1:212525996(+) A-I      intronic chr1:212526034(+) A-I      intronic chr1:212525504(+) A-I      intronic chr1:212515100(+) A-I      intronic chr1:212515184(+) A-I      intronic chr1:212511922(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PPP2R5A	chr1:212519608(+) A-I intron -    21960545 chr1:212519610(+) A-I intron -    21960545 chr1:212523327(+) A-I intron -    21960545 chr1:212523340(+) A-I intron -    21960545 chr1:212523377(+) A-I intron -    21960545 chr1:212523378(+) A-I intron -    21960545 chr1:212525850(+) A-I intron -    21960545 chr1:212523352(+) T-C intron -    22484847 chr1:212508560(+) A-G intron -    22484847 chr1:212508647(+) A-G intron -    22484847 chr1:212508662(+) A-G intron -    22484847 chr1:212509619(+) A-G intron -    22484847 chr1:212511864(+) A-G intron -    22484847 chr1:212511867(+) A-G intron -    22484847 chr1:212511919(+) A-G intron -    22484847 chr1:212511943(+) A-G intron -    22484847 chr1:212511968(+) A-G intron -    22484847 chr1:212511986(+) A-G intron -    22484847 chr1:212512127(+) T-C intron -    22484847 chr1:212512619(+) A-G intron -    22484847 chr1:212512620(+) A-G intron -    22484847 chr1:212512665(+) A-G intron -    22484847 chr1:212517407(+) A-G intron -    22484847 chr1:212517496(+) A-G intron -    22484847 chr1:212517505(+) A-G intron -    22484847 chr1:212518392(+) A-G intron -    22484847 chr1:212523735(+) A-G intron -    22484847 chr1:212523741(+) A-G intron -    22484847 chr1:212523746(+) A-G intron -    22484847 chr1:212523857(+) A-G intron -    22484847 chr1:212524854(+) A-G intron -    22484847 chr1:212524870(+) A-G intron -    22484847 chr1:212524929(+) A-G intron -    22484847 chr1:212524935(+) A-G intron -    22484847 chr1:212524936(+) A-G intron -    22484847 chr1:212525639(+) A-G intron -    22484847 chr1:212525645(+) A-G intron -    22484847 chr1:212525850(+) A-G intron -    22484847 chr1:212525921(+) A-G intron -    22484847 chr1:212526066(+) A-G intron -    22484847 chr1:212527286(+) A-G intron -    22484847 chr1:212527765(+) A-G intron -    22484847 chr1:212527905(+) A-G intron -    22484847 chr1:212530998(+) A-G intron -    22484847 chr1:212531243(+) A-G intron -    22484847 chr1:212531417(+) T-C intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PPP2R5A	chr1:212458971-212458972(+) m6A 5'UTR       24209618//22575960 chr1:212459132-212459133(+) m6A 5'UTR       24209618//25456834 chr1:212459243-212459244(+) m6A 5'UTR       24284625//25456834 chr1:212459250-212459251(+) m6A 5'UTR       24284625//25456834 chr1:212502492-212502493(+) m6A CDS//exon       24284625//25456834//24981863//22575960//22608085 chr1:212502551-212502552(+) m6A CDS//exon       24284625//25456834//24981863//22575960//22608085 chr1:212502560-212502561(+) Cm CDS//exon       - chr1:212502563-212502564(+) m6A CDS//exon       24284625//25456834//24981863//22575960//22608085 chr1:212502603-212502604(+) m6A CDS//exon       24284625//25456834//24981863//22575960//22608085 chr1:212532123-212532124(+) m6A CDS       24981863 chr1:212534057-212534058(+) m6A CDS       24981863 chr1:212534184-212534185(+) m6A 3'UTR       24981863 chr1:212534188-212534189(+) m6A 3'UTR       26404942 chr1:212534255-212534256(+) m6A 3'UTR       24981863//26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	kshv-miR-K12-12-5p	Exosome Primary dendritic cells     21505438
	PPP2R5A	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-12-5p
Interactor2: PPP2R5A

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid
Support Database	VmiReg