Basic Information:

  VIRBase ID:  

VHID00472197

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-12-5p:  MIMAT0003712          MMP2:  NM_001302508     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-12-5p	MMP2
miRBase Accession/Entrez ID	MIMAT0003712	4313
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CLG4//CLG4A//MMP-2//MMP-II//MONA//TBE-1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MMP2	chr16:55539009(+) A-I      intronic chr16:55537995(+) A-I      intronic chr16:55538025(+) A-I      intronic chr16:55533094(+) A-I      intronic chr16:55537949(+) A-I      intronic chr16:55537883(+) A-I      intronic chr16:55539077(+) A-I      intronic chr16:55538004(+) A-I      intronic chr16:55537832(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MMP2	chr16:55513120-55513121(+) m6A 5'UTR//intron       24209618//24981863 chr16:55513164-55513165(+) m6A 5'UTR//intron       24209618//24981863 chr16:55513185-55513186(+) m6A 5'UTR//intron       24209618//24981863 chr16:55513232-55513233(+) m6A 5'UTR//intron       24209618//24981863//27773536 chr16:55513256-55513257(+) m6A 5'UTR//intron       24209618//24981863//27773536 chr16:55513279-55513280(+) m6A 5'UTR//intron       24209618//27773536 chr16:55513527-55513528(+) m6A CDS//intron       24981863 chr16:55513914-55513915(+) m6A 5'UTR//intron       24981863 chr16:55513925-55513926(+) m6A 5'UTR//intron       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	kshv-miR-K12-12-5p	Exosome Primary dendritic cells     21505438
	MMP2	Cytosol HeLa-S3 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-12-5p
Interactor2: MMP2

Evidence Support:

Prediction-Evidence	miRanda//RNAHybrid
Support Database	VmiReg