Detail Information

Basic Information:


  VIRBase ID:  

VHID00470950

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.8589

  Interaction Type:  

Virus-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol kshv-miR-K12-3-3p CAECAM1
miRBase
Accession/Entrez ID
MIMAT0002194 CAECAM1
Organism Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV) Homo sapiens
Category miRNA mRNA
Alias - -

Interaction Network (The top 100 interactions):


Interactor1: kshv-miR-K12-3-3p
Interactor2: CAECAM1

Evidence Support:


Strong-Evidence qPCR
Weak-Evidence Microarray
Support Database ViRBase

References:


PMID 29550353 Target region None
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line HOK cells Interactor2 expression Upregulation
Description Figure 2.Differential expression of host genes in miR-H1 and miR-K12-3-3p transfected HOK.(D) Validation of selected differentially expressed genes by quantitative RT-PCR in a second cohort of HOK cultures. Total RNA isolated from miR-H1, miR-K12-3-3p and control transfected HOK were analyzed for the expression of differentially expressed genes by quantitative RT-PCR.

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