Detail Information

Basic Information:


  VIRBase ID:  

VHID00467590

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-3-5p:           SRSF1:      

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Interactor Information:


Interactor1 Interactor2
Symbol kshv-miR-K12-3-5p SRSF1
miRBase
Accession/Entrez ID		 MIMAT0002193 6426
Organism Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV) Homo sapiens
Category miRNA mRNA
Alias - ASF//SF2//SF2p33//SFRS1//SRp30a

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SRSF1
chr17:56080151(-) A-I      3'UTR
chr17:56080155(-) A-I      3'UTR
chr17:56080116(-) A-I      3'UTR
chr17:56080122(-) A-I      3'UTR
chr17:56080128(-) A-I      3'UTR
chr17:56080425(-) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SRSF1
chr17:56080856-56080857(-) m6A 3'UTR//exon       24981863
chr17:56080870-56080871(-) m6A 3'UTR//exon       24981863
chr17:56080936-56080937(-) m6A 3'UTR//exon       24981863//28052920
chr17:56081006-56081007(-) m6A 3'UTR//exon       24284625//24981863//26404942//27773535
chr17:56081065-56081066(-) m6A 3'UTR//exon       24284625//24981863//26404942//27773535
chr17:56081205-56081206(-) m6A 3'UTR//intron       24284625//24981863//26404942//22575960
chr17:56081234-56081235(-) m6A 3'UTR//intron       24284625//24981863//26404942//22575960
chr17:56081863-56081864(-) Y 3'UTR//intron       26075521
chr17:56082130-56082131(-) m6A 3'UTR//intron       26404942
chr17:56082175-56082176(-) m6A 3'UTR//intron       26404942
chr17:56082185-56082186(-) m6A 3'UTR//intron       26404942
chr17:56082304-56082305(-) Cm 3'UTR//exon       -
chr17:56082401-56082402(-) m6A 3'UTR//CDS//exon       -
chr17:56082483-56082484(-) m6A 3'UTR//exon//intron       -
chr17:56082544-56082545(-) Y 3'UTR//intron       25219674
chr17:56082954-56082955(-) m6A 3'UTR//CDS//intron       22575960
chr17:56083191-56083192(-) m6A 3'UTR//CDS//intron       26404942//22575960
chr17:56083661-56083662(-) m6A exon//intron       22575960
chr17:56083720-56083721(-) m6A 3'UTR//CDS//exon//intron       22575960
chr17:56083799-56083800(-) m6A 3'UTR//CDS//exon//intron       22575960
chr17:56084310-56084311(-) m6A CDS//exon       22575960
chr17:56084339-56084340(-) m6A CDS//exon       22575960
chr17:56084394-56084395(-) Tm CDS//exon       -
chr17:56084406-56084407(-) m6A CDS//exon       24284625//27371828//22575960
chr17:56084413-56084414(-) m6A CDS//exon       24284625//27371828//22575960
chr17:56084421-56084422(-) m6A CDS//exon       24284625//27371828//22575960
chr17:56084460-56084461(-) m6A CDS//exon       24284625//26404942//27371828//22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate kshv-miR-K12-3-5p
Exosome B cell line (Raji)|Primary dendritic cells|T cell line (J77)     21505438
Exosome KSHV-infected lymphoma cell lines (BCBL-1|TY-1)     27611973
Exosome K562 cells     24460325
SRSF1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Membrane HCC cell line (HepG2)|K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: kshv-miR-K12-3-5p
Interactor2: SRSF1

Evidence Support:


Prediction-Evidence miRanda//Targetscan
Support Database VmiReg

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