Basic Information:

  VIRBase ID:  

VHID00467438

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-3-5p:  MIMAT0002193          PLAU:  NM_001319191     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-3-5p	PLAU
miRBase Accession/Entrez ID	MIMAT0002193	5328
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ATF//BDPLT5//QPD//u-PA//UPA//URK

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PLAU	chr10:75670367-75670368(+) m6A exon//intron       24981863 chr10:75670458-75670459(+) m6A exon//intron       24209618//24981863 chr10:75670900-75670901(+) m6A 5'UTR//intron       24209618//24981863 chr10:75671407-75671408(+) m6A 5'UTR//intron       - chr10:75671486-75671487(+) m6A 5'UTR//intron       25456834 chr10:75671505-75671506(+) m6A 5'UTR//intron       25456834 chr10:75671530-75671531(+) m6A 5'UTR//intron       25456834 chr10:75673757-75673758(+) m6A CDS       - chr10:75673829-75673830(+) m6A CDS       - chr10:75673847-75673848(+) m6A CDS       - chr10:75675142-75675143(+) m6A CDS       - chr10:75676150-75676151(+) m6A CDS       - chr10:75676160-75676161(+) m6A CDS       24981863 chr10:75676237-75676238(+) m6A CDS       24209618//24981863 chr10:75676411-75676412(+) m6A 3'UTR       24209618//25456834//24981863//26404942 chr10:75676515-75676516(+) m6A 3'UTR       24209618//25456834//24981863//26404942 chr10:75676586-75676587(+) m6A 3'UTR       24209618//25456834//24981863//26404942 chr10:75676779-75676780(+) m6A 3'UTR       24981863//26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	kshv-miR-K12-3-5p	Exosome B cell line (Raji)|Primary dendritic cells|T cell line (J77)     21505438 Exosome KSHV-infected lymphoma cell lines (BCBL-1|TY-1)     27611973 Exosome K562 cells     24460325
	PLAU	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-3-5p
Interactor2: PLAU

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg