Basic Information:

  VIRBase ID:  

VHID00466265

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-4-3p:  MIMAT0002192          HFM1:  NM_001017975     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-4-3p	HFM1
miRBase Accession/Entrez ID	MIMAT0002192	164045
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	helicase//MER3//POF9//SEC63D1//Si-11//Si-11-6

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	HFM1	chr1:91852808(-) A-I      intronic chr1:91852831(-) A-I      intronic chr1:91852834(-) A-I      intronic chr1:91852847(-) A-I      intronic chr1:91771858(-) A-I      intronic chr1:91855907(-) A-I      intronic chr1:91769316(-) A-I      intronic chr1:91852837(-) A-I      intronic chr1:91852793(-) A-I      intronic chr1:91852801(-) A-I      intronic chr1:91729215(-) A-I      intronic chr1:91771863(-) A-I      intronic chr1:91771876(-) A-I      intronic chr1:91771888(-) A-I      intronic chr1:91855827(-) A-I      intronic chr1:91729064(-) A-I      intronic chr1:91729202(-) A-I      intronic chr1:91810436(-) A-I      intronic chr1:91771299(-) A-I      intronic chr1:91729106(-) A-I      intronic chr1:91823717(-) A-I      intronic chr1:91814285(-) A-I      intronic chr1:91771187(-) A-I      intronic chr1:91855933(-) A-I      intronic chr1:91782908(-) A-I      intronic chr1:91805766(-) A-I      intronic chr1:91771670(-) A-I      intronic chr1:91810452(-) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	HFM1	chr1:91852779-91852780(-) Gm intron       - chr1:91852810-91852811(-) Y intron       16381836//25192136 chr1:91852811-91852812(-) Gm intron       16381836 chr1:91852812-91852813(-) Um intron       16381836 chr1:91852816-91852817(-) Gm intron       16381836 chr1:91852839-91852840(-) Y intron       16381836//25192136 chr1:91852853-91852854(-) Y intron       16381836//25192136 chr1:91852854-91852855(-) Cm intron       16381836 chr1:91852868-91852869(-) Y intron       16381836//25192136 chr1:91852879-91852880(-) Y intron       16381836//25192136 chr1:91852887-91852888(-) Y intron       16381836//25192136 chr1:91852890-91852891(-) Y intron       16381836//25192136 chr1:91852907-91852908(-) Y intron       16381836//25192136 chr1:91852918-91852919(-) Gm intron       16381836 chr1:91852940-91852941(-) Gm intron       16381836 chr1:91852949-91852950(-) Y intron       16381836//25192136 chr1:91852957-91852958(-) Y intron       16381836 chr1:91852998-91852999(-) Y intron       16381836//25192136 chr1:91853004-91853005(-) Um intron       16381836 chr1:91853011-91853012(-) Y intron       16381836//25192136 chr1:91853014-91853015(-) Y intron       16381836//25192136 chr1:91853017-91853018(-) Y intron       16381836//25192136 chr1:91853082-91853083(-) Gm intron       16381836 chr1:91853083-91853084(-) Um intron       16381836 chr1:91853114-91853115(-) Gm intron       16381836 chr1:91870283-91870284(-) m6A 5'UTR//intron       27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	HFM1	Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	kshv-miR-K12-4-3p	Panobinostat       6918837 Nilotinib       644241 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Dovitinib       135398510 Crizotinib       11626560 Nvp-aew541       11476171 Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-4-3p
Interactor2: HFM1

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg