Basic Information:

  VIRBase ID:  

VHID00465731

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-4-3p:  MIMAT0002192          PHF6:  NM_032335     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-4-3p	PHF6
miRBase Accession/Entrez ID	MIMAT0002192	84295
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BFLS//BORJ//CENP-31

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PHF6	chrX:133535215(+) A-I      intronic chrX:133535214(+) A-I      intronic chrX:133535206(+) A-I      intronic chrX:133535179(+) A-I      intronic chrX:133535178(+) A-I      intronic chrX:133535216(+) A-I      intronic chrX:133517011(+) A-I      intronic chrX:133518735(+) A-I      intronic chrX:133531493(+) A-I      intronic chrX:133533781(+) A-I      intronic chrX:133554722(+) A-I      intronic chrX:133554809(+) A-I      intronic chrX:133534221(+) A-I      intronic chrX:133536236(+) A-I      intronic chrX:133532395(+) A-I      intronic chrX:133554678(+) A-I      intronic chrX:133554702(+) A-I      intronic chrX:133554813(+) A-I      intronic chrX:133534173(+) A-I      intronic chrX:133534140(+) A-I      intronic chrX:133518888(+) A-I      intronic chrX:133532159(+) A-I      intronic chrX:133531540(+) A-I      intronic chrX:133532410(+) A-I      intronic chrX:133534354(+) A-I      intronic chrX:133517163(+) A-I      intronic chrX:133532167(+) A-I      intronic chrX:133534242(+) A-I      intronic chrX:133532261(+) A-I      intronic chrX:133534351(+) A-I      intronic chrX:133545122(+) A-I      intronic chrX:133532316(+) A-I      intronic chrX:133529066(+) A-I      intronic chrX:133517256(+) A-I      intronic chrX:133542927(+) A-I      intronic chrX:133532258(+) A-I      intronic chrX:133554740(+) A-I      intronic chrX:133534392(+) A-I      intronic chrX:133536286(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PHF6	chrX:133549138(+) A-I exon CDS    15342557 chrX:133552501(+) A-I intron -    15342557 chrX:133552894(+) A-I intron -    15342557 chrX:133552896(+) A-I intron -    15342557 chrX:133553071(+) A-I intron -    15342557   //15258596 chrX:133553150(+) A-I intron -    15342557   //15258596 chrX:133554078(+) A-I intron -    15342557   //15258596 chrX:133533373(+) A-G intron -    22484847 chrX:133533401(+) A-G intron -    22484847 chrX:133533801(+) A-G intron -    22484847 chrX:133540414(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PHF6	chrX:133527963-133527964(+) m6A CDS       27773535 chrX:133547545-133547546(+) m6A CDS       24981863//27773535 chrX:133547551-133547552(+) m6A CDS       24981863//27773535 chrX:133547609-133547610(+) m6A CDS       24981863//27773535 chrX:133551261-133551262(+) m6A CDS       27773535 chrX:133551289-133551290(+) m6A CDS       27773535 chrX:133551340-133551341(+) m6A 3'UTR//intron       27773535 chrX:133551363-133551364(+) m6A 3'UTR//intron       27773535 chrX:133554327-133554328(+) m6A 3'UTR//intron       24981863 chrX:133559355-133559356(+) m6A CDS       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PHF6	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	kshv-miR-K12-4-3p	Panobinostat       6918837 Nilotinib       644241 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Dovitinib       135398510 Crizotinib       11626560 Nvp-aew541       11476171 Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-4-3p
Interactor2: PHF6

Evidence Support:

Prediction-Evidence	cRep//miRanda//Targetscan
Support Database	RepTar//VmiReg