Basic Information:

  VIRBase ID:  

VHID00464069

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-4-3p:  MIMAT0002192          GOSR2:  NR_148350     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-4-3p	GOSR2
miRBase Accession/Entrez ID	MIMAT0002192	9570
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	Bos1//EPM6//GS27

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	GOSR2	chr17:45013449(+) A-I      3'UTR chr17:45011790(+) A-I      intronic chr17:45011822(+) A-I      intronic chr17:45015375(+) A-I      intronic chr17:45015320(+) A-I      intronic chr17:45011754(+) A-I      intronic chr17:45015367(+) A-I      intronic chr17:45011242(+) A-I      intronic chr17:45011821(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	GOSR2	chr17:45000486-45000487(+) m6A 5'UTR       25456834//24981863 chr17:45000937-45000938(+) m6A 5'UTR//exon//intron       24981863 chr17:45000951-45000952(+) m6A 5'UTR//exon//intron       24981863 chr17:45006932-45006933(+) m6A CDS//exon       24284625//24981863 chr17:45006970-45006971(+) m6A exon//intron       24981863 chr17:45008494-45008495(+) m6A CDS//exon       24981863 chr17:45008570-45008571(+) m6A CDS//exon       24981863 chr17:45009666-45009667(+) m6A 3'UTR//intron       - chr17:45009681-45009682(+) m6A 3'UTR//intron       - chr17:45009701-45009702(+) m6A 3'UTR//intron       - chr17:45009722-45009723(+) m6A 3'UTR//intron       - chr17:45009727-45009728(+) m6A 3'UTR//intron       - chr17:45009733-45009734(+) m6A 3'UTR//intron       - chr17:45009755-45009756(+) m6A 3'UTR//intron       - chr17:45009761-45009762(+) m6A 3'UTR//intron       - chr17:45012507-45012508(+) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535 chr17:45012514-45012515(+) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535 chr17:45012522-45012523(+) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535 chr17:45012554-45012555(+) m6A CDS//intron       24284625//24981863 chr17:45012653-45012654(+) m6A 3'UTR//intron       24981863 chr17:45013934-45013935(+) m6A 3'UTR//intron       - chr17:45015967-45015968(+) m6A CDS       24284625//24209618//24981863//26404942//22608085 chr17:45016052-45016053(+) m6A CDS       24284625//24209618//24981863//22608085 chr17:45016148-45016149(+) m6A 3'UTR//intron       24284625//24209618//24981863 chr17:45017940-45017941(+) m6A CDS//intron       25456834//24981863 chr17:45017994-45017995(+) m6A 3'UTR//intron       25456834//24981863 chr17:45018033-45018034(+) m6A 3'UTR//intron       25456834//24981863//22608085 chr17:45018042-45018043(+) m6A 3'UTR//intron       25456834//24981863//22608085 chr17:45018101-45018102(+) m6A 3'UTR//intron       24981863//22608085 chr17:45041069-45041070(+) m6A CDS//intron       24981863//22608085 chr17:45043901-45043902(+) m6A CDS       24284625//24209618//24981863//22608085 chr17:45043930-45043931(+) m6A CDS       24284625//24209618//24981863//22608085 chr17:45043936-45043937(+) m6A CDS       24284625//24209618//24981863//22608085 chr17:45044029-45044030(+) m6A CDS       24284625//24209618//24981863//22608085 chr17:45044047-45044048(+) m6A CDS       24284625//24209618//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	GOSR2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	kshv-miR-K12-4-3p	Panobinostat       6918837 Nilotinib       644241 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Dovitinib       135398510 Crizotinib       11626560 Nvp-aew541       11476171 Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-4-3p
Interactor2: GOSR2

Evidence Support:

Prediction-Evidence	cRep//miRanda//RNAHybrid
Support Database	RepTar//VmiReg