Basic Information:

  VIRBase ID:  

VHID00463681

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.9124

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-4-3p:  MIMAT0002192          SOS1:  NM_001382395     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-4-3p	SOS1
miRBase Accession/Entrez ID	MIMAT0002192	6654
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	GF1//GGF1//GINGF//HGF//NS4//SOS-1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SOS1	chr2:39339121(-) A-I      intronic chr2:39340050(-) A-I      intronic chr2:39340453(-) A-I      intronic chr2:39340464(-) A-I      intronic chr2:39340488(-) A-I      intronic chr2:39341940(-) A-I      intronic chr2:39341976(-) A-I      intronic chr2:39341995(-) A-I      intronic chr2:39342653(-) A-I      intronic chr2:39342704(-) A-I      intronic chr2:39280051(-) A-I      intronic chr2:39292401(-) A-I      intronic chr2:39292479(-) A-I      intronic chr2:39292485(-) A-I      intronic chr2:39291626(-) A-I      intronic chr2:39280194(-) A-I      intronic chr2:39291566(-) A-I      intronic chr2:39291576(-) A-I      intronic chr2:39291580(-) A-I      intronic chr2:39291581(-) A-I      intronic chr2:39291586(-) A-I      intronic chr2:39291588(-) A-I      intronic chr2:39291600(-) A-I      intronic chr2:39291605(-) A-I      intronic chr2:39291610(-) A-I      intronic chr2:39291612(-) A-I      intronic chr2:39291613(-) A-I      intronic chr2:39291616(-) A-I      intronic chr2:39291617(-) A-I      intronic chr2:39291618(-) A-I      intronic chr2:39291496(-) A-I      intronic chr2:39237388(-) A-I      intronic chr2:39237371(-) A-I      intronic chr2:39255166(-) A-I      intronic chr2:39237345(-) A-I      intronic chr2:39291565(-) A-I      intronic chr2:39291650(-) A-I      intronic chr2:39292369(-) A-I      intronic chr2:39292370(-) A-I      intronic chr2:39292372(-) A-I      intronic chr2:39292390(-) A-I      intronic chr2:39292400(-) A-I      intronic chr2:39291501(-) A-I      intronic chr2:39260924(-) A-I      intronic chr2:39288667(-) A-I      intronic chr2:39339066(-) A-I      intronic chr2:39339095(-) A-I      intronic chr2:39260905(-) A-I      intronic chr2:39291555(-) A-I      intronic chr2:39260879(-) A-I      intronic chr2:39260874(-) A-I      intronic chr2:39255167(-) A-I      intronic chr2:39255165(-) A-I      intronic chr2:39291532(-) A-I      intronic chr2:39255148(-) A-I      intronic chr2:39255139(-) A-I      intronic chr2:39237405(-) A-I      intronic chr2:39291533(-) A-I      intronic chr2:39291534(-) A-I      intronic chr2:39291541(-) A-I      intronic chr2:39292402(-) A-I      intronic chr2:39292405(-) A-I      intronic chr2:39292407(-) A-I      intronic chr2:39292418(-) A-I      intronic chr2:39292419(-) A-I      intronic chr2:39292422(-) A-I      intronic chr2:39292477(-) A-I      intronic chr2:39291556(-) A-I      intronic chr2:39291560(-) A-I      intronic chr2:39291563(-) A-I      intronic chr2:39291564(-) A-I      intronic chr2:39260897(-) A-I      intronic chr2:39260881(-) A-I      intronic chr2:39339113(-) A-I      intronic chr2:39325906(-) A-I      intronic chr2:39325817(-) A-I      intronic chr2:39325787(-) A-I      intronic chr2:39325786(-) A-I      intronic chr2:39324702(-) A-I      intronic chr2:39323980(-) A-I      intronic chr2:39323964(-) A-I      intronic chr2:39323915(-) A-I      intronic chr2:39323908(-) A-I      intronic chr2:39323859(-) A-I      intronic chr2:39323837(-) A-I      intronic chr2:39323832(-) A-I      intronic chr2:39323770(-) A-I      intronic chr2:39319409(-) A-I      intronic chr2:39257116(-) A-I      intronic chr2:39318305(-) A-I      intronic chr2:39318241(-) A-I      intronic chr2:39318223(-) A-I      intronic chr2:39318189(-) A-I      intronic chr2:39318174(-) A-I      intronic chr2:39318123(-) A-I      intronic chr2:39318115(-) A-I      intronic chr2:39318102(-) A-I      intronic chr2:39317798(-) A-I      intronic chr2:39317224(-) A-I      intronic chr2:39317156(-) A-I      intronic chr2:39317105(-) A-I      intronic chr2:39317102(-) A-I      intronic chr2:39317049(-) A-I      intronic chr2:39314988(-) A-I      intronic chr2:39314976(-) A-I      intronic chr2:39314968(-) A-I      intronic chr2:39314827(-) A-I      intronic chr2:39314156(-) A-I      intronic chr2:39314150(-) A-I      intronic chr2:39314149(-) A-I      intronic chr2:39314122(-) A-I      intronic chr2:39314092(-) A-I      intronic chr2:39314091(-) A-I      intronic chr2:39314082(-) A-I      intronic chr2:39314052(-) A-I      intronic chr2:39314051(-) A-I      intronic chr2:39314050(-) A-I      intronic chr2:39314022(-) A-I      intronic chr2:39314021(-) A-I      intronic chr2:39314016(-) A-I      intronic chr2:39260059(-) A-I      intronic chr2:39259998(-) A-I      intronic chr2:39259978(-) A-I      intronic chr2:39259916(-) A-I      intronic chr2:39257105(-) A-I      intronic chr2:39257104(-) A-I      intronic chr2:39255168(-) A-I      intronic chr2:39255104(-) A-I      intronic chr2:39230120(-) A-I      intronic chr2:39230075(-) A-I      intronic chr2:39230034(-) A-I      intronic chr2:39280207(-) A-I      intronic chr2:39280076(-) A-I      intronic chr2:39280072(-) A-I      intronic chr2:39275824(-) A-I      intronic chr2:39273649(-) A-I      intronic chr2:39273141(-) A-I      intronic chr2:39272982(-) A-I      intronic chr2:39272974(-) A-I      intronic chr2:39272966(-) A-I      intronic chr2:39272942(-) A-I      intronic chr2:39269709(-) A-I      intronic chr2:39267416(-) A-I      intronic chr2:39229359(-) A-I      intronic chr2:39267215(-) A-I      intronic chr2:39281174(-) A-I      intronic chr2:39260959(-) A-I      intronic chr2:39344281(-) A-I      intronic chr2:39260344(-) A-I      intronic chr2:39230002(-) A-I      intronic chr2:39228477(-) A-I      intronic chr2:39220503(-) A-I      intronic chr2:39333186(-) A-I      intronic chr2:39342632(-) A-I      intronic chr2:39342591(-) A-I      intronic chr2:39342590(-) A-I      intronic chr2:39342006(-) A-I      intronic chr2:39341990(-) A-I      intronic chr2:39341952(-) A-I      intronic chr2:39341938(-) A-I      intronic chr2:39341911(-) A-I      intronic chr2:39341908(-) A-I      intronic chr2:39260206(-) A-I      intronic chr2:39341906(-) A-I      intronic chr2:39341902(-) A-I      intronic chr2:39341808(-) A-I      intronic chr2:39341681(-) A-I      intronic chr2:39341569(-) A-I      intronic chr2:39341556(-) A-I      intronic chr2:39341530(-) A-I      intronic chr2:39341523(-) A-I      intronic chr2:39341471(-) A-I      intronic chr2:39340456(-) A-I      intronic chr2:39340400(-) A-I      intronic chr2:39340397(-) A-I      intronic chr2:39340032(-) A-I      intronic chr2:39339988(-) A-I      intronic chr2:39339710(-) A-I      intronic chr2:39339122(-) A-I      intronic chr2:39338906(-) A-I      intronic chr2:39338262(-) A-I      intronic chr2:39338250(-) A-I      intronic chr2:39338157(-) A-I      intronic chr2:39335934(-) A-I      intronic chr2:39335912(-) A-I      intronic chr2:39333278(-) A-I      intronic chr2:39333266(-) A-I      intronic chr2:39333264(-) A-I      intronic chr2:39333237(-) A-I      intronic chr2:39230091(-) A-I      intronic chr2:39333229(-) A-I      intronic chr2:39333192(-) A-I      intronic chr2:39333166(-) A-I      intronic chr2:39333141(-) A-I      intronic chr2:39281069(-) A-I      intronic chr2:39281177(-) A-I      intronic chr2:39281180(-) A-I      intronic chr2:39281197(-) A-I      intronic chr2:39281206(-) A-I      intronic chr2:39281207(-) A-I      intronic chr2:39281236(-) A-I      intronic chr2:39281243(-) A-I      intronic chr2:39281249(-) A-I      intronic chr2:39281273(-) A-I      intronic chr2:39281308(-) A-I      intronic chr2:39281324(-) A-I      intronic chr2:39281349(-) A-I      intronic chr2:39288696(-) A-I      intronic chr2:39289367(-) A-I      intronic chr2:39289459(-) A-I      intronic chr2:39344307(-) A-I      intronic chr2:39333107(-) A-I      intronic chr2:39333009(-) A-I      intronic chr2:39332919(-) A-I      intronic chr2:39332866(-) A-I      intronic chr2:39332539(-) A-I      intronic chr2:39332525(-) A-I      intronic chr2:39330090(-) A-I      intronic chr2:39330013(-) A-I      intronic chr2:39329974(-) A-I      intronic chr2:39329918(-) A-I      intronic chr2:39327122(-) A-I      intronic chr2:39327076(-) A-I      intronic chr2:39326977(-) A-I      intronic chr2:39325986(-) A-I      intronic chr2:39325943(-) A-I      intronic chr2:39289497(-) A-I      intronic chr2:39301408(-) A-I      intronic chr2:39325908(-) A-I      intronic chr2:39301409(-) A-I      intronic chr2:39301439(-) A-I      intronic chr2:39305946(-) A-I      intronic chr2:39305968(-) A-I      intronic chr2:39305984(-) A-I      intronic chr2:39306003(-) A-I      intronic chr2:39306053(-) A-I      intronic chr2:39306089(-) A-I      intronic chr2:39306741(-) A-I      intronic chr2:39306747(-) A-I      intronic chr2:39306760(-) A-I      intronic chr2:39306764(-) A-I      intronic chr2:39306773(-) A-I      intronic chr2:39306829(-) A-I      intronic chr2:39344246(-) A-I      intronic chr2:39306884(-) A-I      intronic chr2:39308854(-) A-I      intronic chr2:39325948(-) A-I      intronic chr2:39308858(-) A-I      intronic chr2:39343977(-) A-I      intronic chr2:39343897(-) A-I      intronic chr2:39312325(-) A-I      intronic chr2:39312439(-) A-I      intronic chr2:39312440(-) A-I      intronic chr2:39343760(-) A-I      intronic chr2:39342858(-) A-I      intronic chr2:39342852(-) A-I      intronic chr2:39342830(-) A-I      intronic chr2:39342806(-) A-I      intronic chr2:39342777(-) A-I      intronic chr2:39342724(-) A-I      intronic chr2:39342720(-) A-I      intronic chr2:39342701(-) A-I      intronic chr2:39342647(-) A-I      intronic chr2:39342639(-) A-I      intronic chr2:39288597(-) A-I      intronic chr2:39265620(-) A-I      intronic chr2:39344216(-) A-I      intronic chr2:39318261(-) A-I      intronic chr2:39327846(-) A-I      intronic chr2:39338211(-) A-I      intronic chr2:39324784(-) A-I      intronic chr2:39339671(-) A-I      intronic chr2:39333320(-) A-I      intronic chr2:39343793(-) A-I      intronic chr2:39324985(-) A-I      intronic chr2:39339663(-) A-I      intronic chr2:39306925(-) A-I      intronic chr2:39339637(-) A-I      intronic chr2:39271417(-) A-I      intronic chr2:39271312(-) A-I      intronic chr2:39317050(-) A-I      intronic chr2:39260840(-) A-I      intronic chr2:39343794(-) A-I      intronic chr2:39274879(-) A-I      intronic chr2:39339595(-) A-I      intronic chr2:39325930(-) A-I      intronic chr2:39333202(-) A-I      intronic chr2:39288707(-) A-I      intronic chr2:39324842(-) A-I      intronic chr2:39281070(-) A-I      intronic chr2:39220534(-) A-I      intronic chr2:39260019(-) A-I      intronic chr2:39315039(-) A-I      intronic chr2:39340538(-) A-I      intronic chr2:39271371(-) A-I      intronic chr2:39342688(-) A-I      intronic chr2:39339064(-) A-I      intronic chr2:39336224(-) A-I      intronic chr2:39342012(-) A-I      intronic chr2:39341875(-) A-I      intronic chr2:39339583(-) A-I      intronic chr2:39268331(-) A-I      intronic chr2:39255100(-) A-I      intronic chr2:39327017(-) A-I      intronic chr2:39292132(-) A-I      intronic chr2:39342746(-) A-I      intronic chr2:39318299(-) A-I      intronic chr2:39296459(-) A-I      intronic chr2:39333035(-) A-I      intronic chr2:39344298(-) A-I      intronic chr2:39332782(-) A-I      intronic chr2:39252551(-) A-I      intronic chr2:39317181(-) A-I      intronic chr2:39335958(-) A-I      intronic chr2:39267425(-) A-I      intronic chr2:39260779(-) A-I      intronic chr2:39340172(-) A-I      intronic chr2:39342778(-) A-I      intronic chr2:39296242(-) A-I      intronic chr2:39228377(-) A-I      intronic chr2:39296826(-) A-I      intronic chr2:39324881(-) A-I      intronic chr2:39327149(-) A-I      intronic chr2:39318192(-) A-I      intronic chr2:39336333(-) A-I      intronic chr2:39343845(-) A-I      intronic chr2:39260314(-) A-I      intronic chr2:39335785(-) A-I      intronic chr2:39220518(-) A-I      intronic chr2:39325774(-) A-I      intronic chr2:39238104(-) A-I      intronic chr2:39335808(-) A-I      intronic chr2:39327018(-) A-I      intronic chr2:39344235(-) A-I      intronic chr2:39340058(-) A-I      intronic chr2:39336254(-) A-I      intronic chr2:39339009(-) A-I      intronic chr2:39296269(-) A-I      intronic chr2:39317198(-) A-I      intronic chr2:39252619(-) A-I      intronic chr2:39341352(-) A-I      intronic chr2:39271381(-) A-I      intronic chr2:39324843(-) A-I      intronic chr2:39341989(-) A-I      intronic chr2:39296862(-) A-I      intronic chr2:39338976(-) A-I      intronic chr2:39275647(-) A-I      intronic chr2:39252629(-) A-I      intronic chr2:39339975(-) A-I      intronic chr2:39229988(-) A-I      intronic chr2:39343930(-) A-I      intronic chr2:39271223(-) A-I      intronic chr2:39336228(-) A-I      intronic chr2:39344364(-) A-I      intronic chr2:39338938(-) A-I      intronic chr2:39275715(-) A-I      intronic chr2:39343858(-) A-I      intronic chr2:39260873(-) A-I      intronic chr2:39344440(-) A-I      intronic chr2:39336148(-) A-I      intronic chr2:39335918(-) A-I      intronic chr2:39342621(-) A-I      intronic chr2:39252628(-) A-I      intronic chr2:39340014(-) A-I      intronic chr2:39344340(-) A-I      intronic chr2:39296485(-) A-I      intronic chr2:39339567(-) A-I      intronic chr2:39296315(-) A-I      intronic chr2:39340008(-) A-I      intronic chr2:39342694(-) A-I      intronic chr2:39339035(-) A-I      intronic chr2:39344308(-) A-I      intronic chr2:39327090(-) A-I      intronic chr2:39343854(-) A-I      intronic chr2:39296390(-) A-I      intronic chr2:39280182(-) A-I      intronic chr2:39340424(-) A-I      intronic chr2:39342782(-) A-I      intronic chr2:39317751(-) A-I      intronic chr2:39280111(-) A-I      intronic chr2:39327061(-) A-I      intronic chr2:39296236(-) A-I      intronic chr2:39341715(-) A-I      intronic chr2:39325777(-) A-I      intronic chr2:39341651(-) A-I      intronic chr2:39317754(-) A-I      intronic chr2:39280247(-) A-I      intronic chr2:39328053(-) A-I      intronic chr2:39275770(-) A-I      intronic chr2:39318070(-) A-I      intronic chr2:39336122(-) A-I      intronic chr2:39258708(-) A-I      intronic chr2:39339029(-) A-I      intronic chr2:39342787(-) A-I      intronic chr2:39271315(-) A-I      intronic chr2:39324888(-) A-I      intronic chr2:39260929(-) A-I      intronic chr2:39335842(-) A-I      intronic chr2:39344338(-) A-I      intronic chr2:39339681(-) A-I      intronic chr2:39343862(-) A-I      intronic chr2:39275666(-) A-I      intronic chr2:39332929(-) A-I      intronic chr2:39339089(-) A-I      intronic chr2:39339587(-) A-I      intronic chr2:39332531(-) A-I      intronic chr2:39342716(-) A-I      intronic chr2:39260279(-) A-I      intronic chr2:39324869(-) A-I      intronic chr2:39340429(-) A-I      intronic chr2:39295096(-) A-I      intronic chr2:39340557(-) A-I      intronic chr2:39339571(-) A-I      intronic chr2:39344441(-) A-I      intronic chr2:39326937(-) A-I      intronic chr2:39340130(-) A-I      intronic chr2:39344337(-) A-I      intronic chr2:39317674(-) A-I      intronic chr2:39342628(-) A-I      intronic chr2:39343909(-) A-I      intronic chr2:39253414(-) A-I      intronic chr2:39317057(-) A-I      intronic chr2:39296404(-) A-I      intronic chr2:39258705(-) A-I      intronic chr2:39271272(-) A-I      intronic chr2:39341870(-) A-I      intronic chr2:39269677(-) A-I      intronic chr2:39344285(-) A-I      intronic chr2:39281141(-) A-I      intronic chr2:39333249(-) A-I      intronic chr2:39271410(-) A-I      intronic chr2:39280128(-) A-I      intronic chr2:39317169(-) A-I      intronic chr2:39273058(-) A-I      intronic chr2:39238201(-) A-I      intronic chr2:39332517(-) A-I      intronic chr2:39340547(-) A-I      intronic chr2:39340071(-) A-I      intronic chr2:39343910(-) A-I      intronic chr2:39340170(-) A-I      intronic chr2:39238175(-) A-I      intronic chr2:39341652(-) A-I      intronic chr2:39317725(-) A-I      intronic chr2:39327130(-) A-I      intronic chr2:39338274(-) A-I      intronic chr2:39280048(-) A-I      intronic chr2:39327104(-) A-I      intronic chr2:39317755(-) A-I      intronic chr2:39335773(-) A-I      intronic chr2:39255123(-) A-I      intronic chr2:39339923(-) A-I      intronic chr2:39341876(-) A-I      intronic chr2:39342828(-) A-I      intronic chr2:39318289(-) A-I      intronic chr2:39326982(-) A-I      intronic chr2:39253452(-) A-I      intronic chr2:39317159(-) A-I      intronic chr2:39340439(-) A-I      intronic chr2:39317737(-) A-I      intronic chr2:39343853(-) A-I      intronic chr2:39325866(-) A-I      intronic chr2:39339647(-) A-I      intronic chr2:39327060(-) A-I      intronic chr2:39238133(-) A-I      intronic chr2:39288669(-) A-I      intronic chr2:39327085(-) A-I      intronic chr2:39343754(-) A-I      intronic chr2:39260062(-) A-I      intronic chr2:39336253(-) A-I      intronic chr2:39314894(-) A-I      intronic chr2:39343776(-) A-I      intronic chr2:39271376(-) A-I      intronic chr2:39294997(-) A-I      intronic chr2:39280114(-) A-I      intronic chr2:39327003(-) A-I      intronic chr2:39339689(-) A-I      intronic chr2:39275774(-) A-I      intronic chr2:39288705(-) A-I      intronic chr2:39344273(-) A-I      intronic chr2:39324883(-) A-I      intronic chr2:39280211(-) A-I      intronic chr2:39288640(-) A-I      intronic chr2:39344266(-) A-I      intronic chr2:39324885(-) A-I      intronic chr2:39332847(-) A-I      intronic chr2:39296868(-) A-I      intronic chr2:39325818(-) A-I      intronic chr2:39317673(-) A-I      intronic chr2:39257628(-) A-I      intronic chr2:39344374(-) A-I      intronic chr2:39255145(-) A-I      intronic chr2:39340017(-) A-I      intronic chr2:39333233(-) A-I      intronic chr2:39318188(-) A-I      intronic chr2:39294280(-) A-I      intronic chr2:39228331(-) A-I      intronic chr2:39228342(-) A-I      intronic chr2:39308154(-) A-I      intronic chr2:39341512(-) A-I      intronic chr2:39228273(-) A-I      intronic chr2:39342805(-) A-I      intronic chr2:39333178(-) A-I      intronic chr2:39338905(-) A-I      intronic chr2:39327839(-) A-I      intronic chr2:39292037(-) A-I      intronic chr2:39341985(-) A-I      intronic chr2:39328067(-) A-I      intronic chr2:39336160(-) A-I      intronic chr2:39327835(-) A-I      intronic chr2:39273125(-) A-I      intronic chr2:39314987(-) A-I      intronic chr2:39332537(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SOS1	chr2:39275647(-) A-I intron -    15545495 chr2:39275666(-) A-I intron -    15545495 chr2:39275710(-) A-I intron -    15545495 chr2:39275715(-) A-I intron -    15545495 chr2:39275770(-) A-I intron -    15545495 chr2:39275774(-) A-I intron -    15545495 chr2:39324774(-) A-I intron -    15342557 chr2:39324837(-) A-I intron -    15342557 chr2:39324842(-) A-I intron -    15342557 chr2:39324843(-) A-I intron -    15342557 chr2:39324869(-) A-I intron -    15342557 chr2:39324881(-) A-I intron -    15342557 chr2:39324885(-) A-I intron -    15342557 chr2:39324956(-) A-I intron -    15342557 chr2:39325818(-) A-I intron -    15342557 chr2:39220142(-) A-I intron -    22327324 chr2:39280049(-) A-I intron -    22327324 chr2:39292442(-) A-I intron -    22327324 chr2:39292449(-) A-I intron -    22327324 chr2:39339009(-) A-I intron -    22327324 chr2:39339577(-) A-I intron -    22327324 chr2:39340538(-) A-I intron -    22327324 chr2:39340547(-) A-I intron -    22327324 chr2:39342694(-) A-I intron -    22327324 chr2:39342787(-) A-I intron -    22327324 chr2:39340058(-) A-I intron -    21960545 chr2:39340068(-) A-I intron -    21960545 chr2:39292442(-) A-G intron -    22484847 chr2:39220142(-) A-G intron -    22484847 chr2:39220179(-) A-G intron -    22484847 chr2:39220185(-) A-G intron -    22484847 chr2:39220186(-) A-G intron -    22484847 chr2:39220205(-) A-G intron -    22484847 chr2:39229988(-) A-G intron -    22484847 chr2:39253414(-) A-G intron -    22484847 chr2:39253452(-) A-G intron -    22484847 chr2:39255160(-) G-A intron -    22484847 chr2:39255161(-) T-C intron -    22484847 chr2:39260314(-) A-G intron -    22484847 chr2:39271315(-) A-G intron -    22484847 chr2:39271326(-) A-G intron -    22484847 chr2:39271400(-) A-G intron -    22484847 chr2:39271410(-) A-G intron -    22484847 chr2:39271417(-) A-G intron -    22484847 chr2:39273058(-) A-G intron -    22484847 chr2:39280049(-) A-G intron -    22484847 chr2:39280111(-) A-G intron -    22484847 chr2:39292037(-) A-G intron -    22484847 chr2:39294997(-) A-G intron -    22484847 chr2:39295096(-) A-G intron -    22484847 chr2:39296236(-) A-G intron -    22484847 chr2:39296315(-) A-G intron -    22484847 chr2:39301597(-) C-T intron -    22484847 chr2:39306923(-) A-G intron -    22484847 chr2:39306925(-) A-G intron -    22484847 chr2:39314147(-) A-G intron -    22484847 chr2:39314230(-) A-G intron -    22484847 chr2:39314935(-) A-G intron -    22484847 chr2:39317050(-) A-G intron -    22484847 chr2:39317057(-) A-G intron -    22484847 chr2:39317159(-) A-G intron -    22484847 chr2:39317169(-) A-G intron -    22484847 chr2:39317181(-) A-G intron -    22484847 chr2:39317198(-) A-G intron -    22484847 chr2:39317616(-) A-G intron -    22484847 chr2:39317620(-) A-G intron -    22484847 chr2:39317640(-) A-G intron -    22484847 chr2:39317671(-) A-G intron -    22484847 chr2:39317673(-) A-G intron -    22484847 chr2:39317737(-) A-G intron -    22484847 chr2:39317754(-) A-G intron -    22484847 chr2:39317755(-) A-G intron -    22484847 chr2:39318070(-) A-G intron -    22484847 chr2:39318124(-) A-G intron -    22484847 chr2:39318188(-) A-G intron -    22484847 chr2:39318192(-) A-G intron -    22484847 chr2:39318261(-) A-G intron -    22484847 chr2:39323862(-) A-G intron -    22484847 chr2:39324843(-) A-G intron -    22484847 chr2:39324985(-) A-G intron -    22484847 chr2:39325818(-) A-G intron -    22484847 chr2:39325841(-) A-G intron -    22484847 chr2:39325866(-) A-G intron -    22484847 chr2:39325930(-) A-G intron -    22484847 chr2:39325944(-) A-G intron -    22484847 chr2:39326982(-) A-G intron -    22484847 chr2:39327003(-) A-G intron -    22484847 chr2:39327018(-) A-G intron -    22484847 chr2:39327060(-) A-G intron -    22484847 chr2:39327061(-) A-G intron -    22484847 chr2:39327085(-) A-G intron -    22484847 chr2:39327090(-) A-G intron -    22484847 chr2:39327104(-) A-G intron -    22484847 chr2:39327130(-) A-G intron -    22484847 chr2:39327131(-) A-G intron -    22484847 chr2:39327147(-) A-G intron -    22484847 chr2:39327149(-) A-G intron -    22484847 chr2:39327846(-) A-G intron -    22484847 chr2:39327977(-) A-G intron -    22484847 chr2:39328053(-) A-G intron -    22484847 chr2:39328067(-) A-G intron -    22484847 chr2:39332517(-) A-G intron -    22484847 chr2:39332537(-) A-G intron -    22484847 chr2:39332847(-) A-G intron -    22484847 chr2:39332875(-) A-G intron -    22484847 chr2:39333035(-) A-G intron -    22484847 chr2:39333178(-) A-G intron -    22484847 chr2:39333233(-) A-G intron -    22484847 chr2:39333239(-) A-G intron -    22484847 chr2:39333309(-) A-G intron -    22484847 chr2:39333320(-) A-G intron -    22484847 chr2:39335842(-) A-G intron -    22484847 chr2:39336224(-) A-G intron -    22484847 chr2:39336228(-) A-G intron -    22484847 chr2:39336253(-) A-G intron -    22484847 chr2:39336254(-) A-G intron -    22484847 chr2:39338274(-) A-G intron -    22484847 chr2:39338880(-) G-A intron -    22484847 chr2:39338905(-) A-G intron -    22484847 chr2:39339009(-) A-G intron -    22484847 chr2:39339577(-) A-G intron -    22484847 chr2:39339583(-) A-G intron -    22484847 chr2:39339587(-) A-G intron -    22484847 chr2:39339645(-) A-G intron -    22484847 chr2:39339663(-) A-G intron -    22484847 chr2:39339671(-) A-G intron -    22484847 chr2:39339675(-) A-G intron -    22484847 chr2:39339681(-) A-G intron -    22484847 chr2:39339689(-) A-G intron -    22484847 chr2:39339715(-) A-G intron -    22484847 chr2:39340000(-) A-G intron -    22484847 chr2:39340017(-) A-G intron -    22484847 chr2:39340068(-) A-G intron -    22484847 chr2:39340071(-) A-G intron -    22484847 chr2:39340080(-) A-G intron -    22484847 chr2:39340177(-) G-T intron -    22484847 chr2:39340429(-) A-G intron -    22484847 chr2:39340439(-) A-G intron -    22484847 chr2:39340446(-) A-G intron -    22484847 chr2:39340538(-) A-G intron -    22484847 chr2:39340547(-) A-G intron -    22484847 chr2:39341884(-) A-G intron -    22484847 chr2:39341932(-) A-G intron -    22484847 chr2:39341985(-) A-G intron -    22484847 chr2:39341989(-) A-G intron -    22484847 chr2:39342628(-) A-G intron -    22484847 chr2:39342688(-) A-G intron -    22484847 chr2:39342694(-) A-G intron -    22484847 chr2:39342746(-) A-G intron -    22484847 chr2:39342778(-) A-G intron -    22484847 chr2:39342787(-) A-G intron -    22484847 chr2:39342805(-) A-G intron -    22484847 chr2:39342828(-) A-G intron -    22484847 chr2:39342838(-) A-G intron -    22484847 chr2:39343766(-) A-G intron -    22484847 chr2:39343776(-) A-G intron -    22484847 chr2:39343853(-) A-G intron -    22484847 chr2:39343905(-) A-G intron -    22484847 chr2:39343909(-) A-G intron -    22484847 chr2:39343930(-) A-G intron -    22484847 chr2:39344273(-) A-G intron -    22484847 chr2:39344308(-) A-G intron -    22484847 chr2:39344337(-) A-G intron -    22484847 chr2:39344338(-) A-G intron -    22484847 chr2:39344339(-) A-G intron -    22484847 chr2:39344340(-) A-G intron -    22484847 chr2:39344343(-) A-G intron -    22484847 chr2:39344364(-) A-G intron -    22484847 chr2:39344374(-) A-G intron -    22484847 chr2:39344440(-) A-G intron -    22484847 chr2:39344441(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SOS1	chr2:39208729-39208730(-) m6A 3'UTR       27773535 chr2:39210965-39210966(-) m6A 3'UTR       27773535 chr2:39211008-39211009(-) m6A 3'UTR       27773535 chr2:39212165-39212166(-) m6A 3'UTR       24284625//24981863//22608085 chr2:39212213-39212214(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr2:39212275-39212276(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr2:39212389-39212390(-) m6A 3'UTR       24284625//25456834//24981863//26404942//27773535//22608085 chr2:39212476-39212477(-) m6A 3'UTR       24284625//25456834//24981863//26404942//27773535//22608085 chr2:39212557-39212558(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr2:39212563-39212564(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr2:39212634-39212635(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr2:39212711-39212712(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr2:39212742-39212743(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr2:39212761-39212762(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr2:39212827-39212828(-) m6A 3'UTR       24284625//24209618//24981863//28052920//27773535//22575960//22608085 chr2:39212861-39212862(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//22575960//22608085 chr2:39212868-39212869(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//22575960//22608085 chr2:39212997-39212998(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//22575960//22608085 chr2:39213041-39213042(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//22575960//22608085 chr2:39213054-39213055(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//22575960//22608085 chr2:39213118-39213119(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr2:39213179-39213180(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr2:39213214-39213215(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085 chr2:39213302-39213303(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:39213312-39213313(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:39213349-39213350(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:39213362-39213363(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr2:39213367-39213368(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr2:39213436-39213437(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085 chr2:39214761-39214762(-) m6A exon//intron       27773535 chr2:39222356-39222357(-) m6A CDS       27773535 chr2:39222392-39222393(-) m6A CDS       27773535 chr2:39222471-39222472(-) m6A CDS       27773535 chr2:39222478-39222479(-) m6A CDS       27773535 chr2:39224084-39224085(-) m6A CDS       27773535 chr2:39224092-39224093(-) m6A CDS       27773535 chr2:39224165-39224166(-) m6A CDS       27773535 chr2:39224539-39224540(-) m6A CDS//exon       24981863 chr2:39234247-39234248(-) m6A CDS//exon       27773535 chr2:39239355-39239356(-) m6A CDS       26404942 chr2:39249744-39249745(-) m6A CDS       24284625//24981863//27773535//22608085 chr2:39249755-39249756(-) m6A CDS       24284625//24981863//27773535//22608085 chr2:39249796-39249797(-) m6A CDS       24284625//24981863//27773535//22608085 chr2:39249964-39249965(-) m6A CDS       27773535//22608085 chr2:39250131-39250132(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22575960//22608085 chr2:39250191-39250192(-) m6A CDS//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr2:39250200-39250201(-) m6A CDS//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr2:39250223-39250224(-) m6A CDS//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr2:39250254-39250255(-) m6A CDS//exon       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085 chr2:39250261-39250262(-) m6A CDS//exon       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085 chr2:39250323-39250324(-) m6A CDS//exon       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085 chr2:39250936-39250937(-) m6A exon//intron       24284625//24981863//27773535//22608085 chr2:39250941-39250942(-) m6A exon//intron       24284625//24981863//27773535//22608085 chr2:39251155-39251156(-) m6A CDS       24284625//24981863//27773535//22608085 chr2:39351332-39351333(-) m6A 5'UTR       27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	SOS1	Chromatin HCC cell line (HepG2)|K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	kshv-miR-K12-4-3p	Panobinostat       6918837 Nilotinib       644241 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Dovitinib       135398510 Crizotinib       11626560 Nvp-aew541       11476171 Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-4-3p
Interactor2: SOS1

Evidence Support:

Strong-Evidence	3'UTR indicator assay
Weak-Evidence	Microarray//PAR-CLIP
Prediction-Evidence	miRanda//PARalyzer//Targetscan
Support Database	RepTar//ViRBase//VIRmiRNA//VmiReg

References:

[1]PMID	22100165	Target region	3'UTR
Source	RepTar//ViRBase//VIRmiRNA//VmiReg	Interactor1 expression	None
Tissue or cell line	BC-1 cells//BC-3 cells	Interactor2 expression	None
Description	We focused this analysis mostly on 3'UTRs of mRNAs encoding proteins with functions of potential relevance to KSHV biology and pathogenesis (Table S11). Thirty-six combinations of 3'UTR indicators and KSHV miRNAs with PAR-CLIP interactions were tested for regulation. Nine of these interactions were independently also predicted by microarray analysis of the BJAB cell pools expressing miR-K1, miR-K4-3p, or miR-K11 described above (i.e. for miR-K1: NMI, RAD21, BCL11A, RFXAP; for miR-K4-3p: TPD52, GRB2, MCC, YWHAB; for miR-K11: WEE1). Targets were representative of the full range of seed match types observed in the libraries (Tables S6 and S11).

[2]PMID	22174674	Target region	None
Source	RepTar//ViRBase//VIRmiRNA//VmiReg	Interactor1 expression	None
Tissue or cell line	EA.hy926 cells	Interactor2 expression	Downregulation
Description	As KSHV putative direct targets we extracted transcripts that were significantly down-regulated significantly in the replicate experiments, and which contained at least one seed-match to one of the KSHV miRNAs. We identified 704 putative direct targets in DG-75 cells (Figure 3B), and 980 putative direct targets in EA.hy926 cells (Figure 3C). A complete list of putative direct targets can be found in Dataset S2 for DG-75 cells and in Dataset S3 for EA.hy926 cells. The overlap between the two datasets contained 153 putative direct targets (Dataset S4).