Basic Information:

  VIRBase ID:  

VHID00463517

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-4-3p:  MIMAT0002192          PRKACB:  NM_207578     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-4-3p	PRKACB
miRBase Accession/Entrez ID	MIMAT0002192	5567
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CAFD2//PKA C-beta//PKACB

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PRKACB	chr1:84683268(+) A-I      intronic chr1:84600619(+) A-I      intronic chr1:84600614(+) A-I      intronic chr1:84600601(+) A-I      intronic chr1:84600559(+) A-I      intronic chr1:84600568(+) A-I      intronic chr1:84573788(+) A-I      intronic chr1:84593872(+) A-I      intronic chr1:84593858(+) A-I      intronic chr1:84593857(+) A-I      intronic chr1:84593841(+) A-I      intronic chr1:84573786(+) A-I      intronic chr1:84683236(+) A-I      intronic chr1:84573755(+) A-I      intronic chr1:84573738(+) A-I      intronic chr1:84573747(+) A-I      intronic chr1:84593831(+) A-I      intronic chr1:84683365(+) A-I      intronic chr1:84683395(+) A-I      intronic chr1:84615068(+) A-I      intronic chr1:84683396(+) A-I      intronic chr1:84683391(+) A-I      intronic chr1:84643444(+) A-I      intronic chr1:84615841(+) A-I      intronic chr1:84615741(+) A-I      intronic chr1:84615693(+) A-I      intronic chr1:84615206(+) A-I      intronic chr1:84615179(+) A-I      intronic chr1:84615127(+) A-I      intronic chr1:84615036(+) A-I      intronic chr1:84595733(+) A-I      intronic chr1:84595720(+) A-I      intronic chr1:84593821(+) A-I      intronic chr1:84593771(+) A-I      intronic chr1:84593748(+) A-I      intronic chr1:84578188(+) A-I      intronic chr1:84643452(+) A-I      intronic chr1:84643216(+) A-I      intronic chr1:84596825(+) A-I      intronic chr1:84683456(+) A-I      intronic chr1:84605622(+) A-I      intronic chr1:84680293(+) A-I      intronic chr1:84643217(+) A-I      intronic chr1:84675623(+) A-I      intronic chr1:84680352(+) A-I      intronic chr1:84652176(+) A-I      intronic chr1:84573576(+) A-I      intronic chr1:84595736(+) A-I      intronic chr1:84660531(+) A-I      intronic chr1:84677888(+) A-I      intronic chr1:84600600(+) A-I      intronic chr1:84595698(+) A-I      intronic chr1:84567920(+) A-I      intronic chr1:84680276(+) A-I      intronic chr1:84684951(+) A-I      intronic chr1:84660547(+) A-I      intronic chr1:84684956(+) A-I      intronic chr1:84595818(+) A-I      intronic chr1:84595793(+) A-I      intronic chr1:84615771(+) A-I      intronic chr1:84600526(+) A-I      intronic chr1:84615069(+) A-I      intronic chr1:84581476(+) A-I      intronic chr1:84660517(+) A-I      intronic chr1:84567919(+) A-I      intronic chr1:84600595(+) A-I      intronic chr1:84683431(+) A-I      intronic chr1:84595756(+) A-I      intronic chr1:84661340(+) A-I      intronic chr1:84596854(+) A-I      intronic chr1:84661449(+) A-I      intronic chr1:84595848(+) A-I      intronic chr1:84567949(+) A-I      intronic chr1:84600124(+) A-I      intronic chr1:84608988(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PRKACB	chr1:84551808(+) A-I intron -    22327324 chr1:84615069(+) A-G intron -    22484847 chr1:84615771(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PRKACB	chr1:84543849-84543850(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22608085 chr1:84543873-84543874(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr1:84543938-84543939(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr1:84544006-84544007(+) m6A 5'UTR       24284625//25456834//24981863//22575960

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PRKACB	Cytosol HCC cell line (HepG2)     - Exosome Blood     - Insoluble cytoplasm K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	kshv-miR-K12-4-3p	Panobinostat       6918837 Nilotinib       644241 Irinotecan       60838 Topotecan       60700 l-685,458       5479543 Palbociclib       5330286 Dovitinib       135398510 Crizotinib       11626560 Nvp-aew541       11476171 Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-4-3p
Interactor2: PRKACB

Evidence Support:

Prediction-Evidence	cRep//miRanda
Support Database	RepTar//VmiReg