Basic Information:

  VIRBase ID:  

VHID00452405

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-6-5p:  MIMAT0002188          DEF8:  NM_001242822     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-6-5p	DEF8
miRBase Accession/Entrez ID	MIMAT0002188	54849
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DEF8	chr16:90017133(+) A-I      intronic chr16:90017210(+) A-I      intronic chr16:90017234(+) A-I      intronic chr16:90026901(+) A-I      intronic chr16:90026898(+) A-I      intronic chr16:90017236(+) A-I      intronic chr16:90017229(+) A-I      intronic chr16:90025967(+) A-I      intronic chr16:90026896(+) A-I      intronic chr16:90028880(+) A-I      intronic chr16:90017225(+) A-I      intronic chr16:90017323(+) A-I      intronic chr16:90018403(+) A-I      intronic chr16:90022673(+) A-I      intronic chr16:90022350(+) A-I      intronic chr16:90016897(+) A-I      intronic chr16:90017138(+) A-I      intronic chr16:90017178(+) A-I      intronic chr16:90017192(+) A-I      intronic chr16:90022774(+) A-I      intronic chr16:90025958(+) A-I      intronic chr16:90023014(+) A-I      intronic chr16:90023026(+) A-I      intronic chr16:90023031(+) A-I      intronic chr16:90023048(+) A-I      intronic chr16:90016962(+) A-I      intronic chr16:90026116(+) A-I      intronic chr16:90018415(+) A-I      intronic chr16:90018516(+) A-I      intronic chr16:90016926(+) A-I      intronic chr16:90026821(+) A-I      intronic chr16:90017130(+) A-I      intronic chr16:90016876(+) A-I      intronic chr16:90017159(+) A-I      intronic chr16:90026904(+) A-I      intronic chr16:90016923(+) A-I      intronic chr16:90018366(+) A-I      intronic chr16:90022788(+) A-I      intronic chr16:90017927(+) A-I      intronic chr16:90017206(+) A-I      intronic chr16:90017782(+) A-I      intronic chr16:90017237(+) A-I      intronic chr16:90018492(+) A-I      intronic chr16:90018682(+) A-I      intronic chr16:90016937(+) A-I      intronic chr16:90017708(+) A-I      intronic chr16:90022611(+) A-I      intronic chr16:90017026(+) A-I      intronic chr16:90023043(+) A-I      intronic chr16:90017259(+) A-I      intronic chr16:90028949(+) A-I      intronic chr16:90022981(+) A-I      intronic chr16:90016998(+) A-I      intronic chr16:90017119(+) A-I      intronic chr16:90022731(+) A-I      intronic chr16:90017228(+) A-I      intronic chr16:90016935(+) A-I      intronic chr16:90022978(+) A-I      intronic chr16:90026818(+) A-I      intronic chr16:90022747(+) A-I      intronic chr16:90022717(+) A-I      intronic chr16:90016995(+) A-I      intronic chr16:90028794(+) A-I      intronic chr16:90016877(+) A-I      intronic chr16:90017330(+) A-I      intronic chr16:90017174(+) A-I      intronic chr16:90028812(+) A-I      intronic chr16:90017263(+) A-I      intronic chr16:90028953(+) A-I      intronic chr16:90022360(+) A-I      intronic chr16:90026112(+) A-I      intronic chr16:90017334(+) A-I      intronic chr16:90017238(+) A-I      intronic chr16:90017314(+) A-I      intronic chr16:90017153(+) A-I      intronic chr16:90022993(+) A-I      intronic chr16:90016914(+) A-I      intronic chr16:90017371(+) A-I      intronic chr16:90017268(+) A-I      intronic chr16:90016978(+) A-I      intronic chr16:90016941(+) A-I      intronic chr16:90017155(+) A-I      intronic chr16:90023131(+) A-I      intronic chr16:90017240(+) A-I      intronic chr16:90025934(+) A-I      intronic chr16:90016981(+) A-I      intronic chr16:90026862(+) A-I      intronic chr16:90017753(+) A-I      intronic chr16:90017223(+) A-I      intronic chr16:90017032(+) A-I      intronic chr16:90018680(+) A-I      intronic chr16:90028926(+) A-I      intronic chr16:90017033(+) A-I      intronic chr16:90017346(+) A-I      intronic chr16:90017243(+) A-I      intronic chr16:90028944(+) A-I      intronic chr16:90017110(+) A-I      intronic chr16:90022789(+) A-I      intronic chr16:90018803(+) A-I      intronic chr16:90023185(+) A-I      intronic chr16:90018886(+) A-I      intronic chr16:90017770(+) A-I      intronic chr16:90016714(+) A-I      intronic chr16:90016497(+) A-I      intronic chr16:90016671(+) A-I      intronic chr16:90016757(+) A-I      intronic chr16:90026880(+) A-I      intronic chr16:90018766(+) A-I      intronic chr16:90028879(+) A-I      intronic chr16:90018737(+) A-I      intronic chr16:90016668(+) A-I      intronic chr16:90028846(+) A-I      intronic chr16:90017290(+) A-I      intronic chr16:90018771(+) A-I      intronic chr16:90018810(+) A-I      intronic chr16:90018826(+) A-I      intronic chr16:90023537(+) A-I      intronic chr16:90016739(+) A-I      intronic chr16:90016759(+) A-I      intronic chr16:90016945(+) A-I      intronic chr16:90017105(+) A-I      intronic chr16:90028805(+) A-I      intronic chr16:90018784(+) A-I      intronic chr16:90016764(+) A-I      intronic chr16:90017836(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	DEF8	chr16:90016668(+) A-I intron -    19478186   //22327324 chr16:90016714(+) A-I intron -    19478186 chr16:90016739(+) A-I intron -    21960545 chr16:90018737(+) A-I intron -    21960545 chr16:90016739(+) A-G intron -    22484847 chr16:90018737(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DEF8	chr16:90015115-90015116(+) m6A 5'UTR       24981863 chr16:90015200-90015201(+) m6A 5'UTR       24284625//25456834//24981863 chr16:90015834-90015835(+) m6A 5'UTR//exon//intron       24284625//25456834//24981863 chr16:90015931-90015932(+) m6A CDS//intron       24284625//24981863 chr16:90020622-90020623(+) m6A 5'UTR//intron       25456834//24981863 chr16:90020734-90020735(+) m6A CDS//exon//intron       24284625//24981863 chr16:90021654-90021655(+) m6A CDS//exon       24284625 chr16:90025502-90025503(+) m6A CDS//exon//intron       27773535 chr16:90025544-90025545(+) m6A CDS//exon//intron       27773535 chr16:90025573-90025574(+) m6A CDS//exon//intron       27773535 chr16:90025602-90025603(+) m6A CDS//exon//intron       27773535 chr16:90029783-90029784(+) m6A CDS//exon//intron       24284625 chr16:90030710-90030711(+) m6A CDS//exon//intron       24284625 chr16:90032270-90032271(+) m6A CDS//exon       24284625//24981863 chr16:90032380-90032381(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863 chr16:90032412-90032413(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863 chr16:90032453-90032454(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863 chr16:90032546-90032547(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr16:90032631-90032632(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr16:90032656-90032657(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr16:90032699-90032700(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr16:90032769-90032770(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr16:90032775-90032776(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr16:90032935-90032936(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085 chr16:90032959-90032960(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085 chr16:90033243-90033244(+) m6A 3'UTR//exon       24284625 chr16:90033423-90033424(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863 chr16:90033449-90033450(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863 chr16:90033471-90033472(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863 chr16:90033613-90033614(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535 chr16:90033706-90033707(+) m6A 3'UTR//exon       24284625//25456834 chr16:90033718-90033719(+) m6A 3'UTR//exon       24284625//25456834 chr16:90033943-90033944(+) m6A 3'UTR//exon       27773535 chr16:90034189-90034190(+) m6A 3'UTR       24284625//24981863//22608085 chr16:90034209-90034210(+) m6A 3'UTR       24284625//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	DEF8	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	kshv-miR-K12-6-5p	l-685,458       5479543

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-6-5p
Interactor2: DEF8

Evidence Support:

Prediction-Evidence	cRep//miRanda//Rep//Targetscan
Support Database	RepTar//VmiReg