Basic Information:

  VIRBase ID:  

VHID00444596

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-9-3p:  MIMAT0002185          ACVR2A:  NM_001278579     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-9-3p	ACVR2A
miRBase Accession/Entrez ID	MIMAT0002185	92
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ACTRII//ACVR2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ACVR2A	chr2:148615448(+) A-I      intronic chr2:148640980(+) A-I      intronic chr2:148640969(+) A-I      intronic chr2:148640945(+) A-I      intronic chr2:148640925(+) A-I      intronic chr2:148639967(+) A-I      intronic chr2:148639961(+) A-I      intronic chr2:148639910(+) A-I      intronic chr2:148639856(+) A-I      intronic chr2:148667447(+) A-I      intronic chr2:148667446(+) A-I      intronic chr2:148667445(+) A-I      intronic chr2:148667276(+) A-I      intronic chr2:148665632(+) A-I      intronic chr2:148665488(+) A-I      intronic chr2:148665469(+) A-I      intronic chr2:148665353(+) A-I      intronic chr2:148621938(+) A-I      intronic chr2:148665465(+) A-I      intronic chr2:148665339(+) A-I      intronic chr2:148640979(+) A-I      intronic chr2:148667399(+) A-I      intronic chr2:148665461(+) A-I      intronic chr2:148647205(+) A-I      intronic chr2:148665487(+) A-I      intronic chr2:148665450(+) A-I      intronic chr2:148612550(+) A-I      intronic chr2:148640943(+) A-I      intronic chr2:148639999(+) A-I      intronic chr2:148665549(+) A-I      intronic chr2:148639864(+) A-I      intronic chr2:148639944(+) A-I      intronic chr2:148612711(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ACVR2A	chr2:148640026(+) A-G intron -    22484847 chr2:148640943(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ACVR2A	chr2:148683723-148683724(+) m6A CDS//exon       24284625//24209618//24981863//22608085 chr2:148684669-148684670(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085 chr2:148684752-148684753(+) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr2:148684778-148684779(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr2:148684876-148684877(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr2:148684883-148684884(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr2:148684906-148684907(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr2:148684971-148684972(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:148685001-148685002(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:148685035-148685036(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:148685042-148685043(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:148685052-148685053(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:148685061-148685062(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr2:148685074-148685075(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr2:148685131-148685132(+) m6A 3'UTR       24981863//22608085 chr2:148685155-148685156(+) m6A 3'UTR       24981863//22608085 chr2:148685188-148685189(+) m6A 3'UTR       24981863//22608085 chr2:148685207-148685208(+) m6A 3'UTR       24981863//22608085 chr2:148685234-148685235(+) m6A 3'UTR       24981863//22608085 chr2:148688013-148688014(+) m6A 3'UTR       27773535 chr2:148688085-148688086(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ACVR2A	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-9-3p
Interactor2: ACVR2A

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg