Basic Information:

  VIRBase ID:  

VHID00442460

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-9-5p:  MIMAT0002184          PNPO:  NM_018129     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-9-5p	PNPO
miRBase Accession/Entrez ID	MIMAT0002184	55163
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	HEL-S-302//PDXPO

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PNPO	chr17:46025270(+) A-I      3'UTR chr17:46025242(+) A-I      3'UTR chr17:46025078(+) A-I      3'UTR chr17:46025154(+) A-I      3'UTR chr17:46025282(+) A-I      3'UTR chr17:46025047(+) A-I      3'UTR chr17:46025034(+) A-I      3'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PNPO	chr17:46025034(+) A-I exon 3'UTR    15258596 chr17:46025047(+) A-I exon 3'UTR    15258596 chr17:46025078(+) A-I exon 3'UTR    15258596 chr17:46026621(+) T-C intron -    21725310

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PNPO	chr17:46018885-46018886(+) m6A 5'UTR       24981863 chr17:46018902-46018903(+) m6A 5'UTR       24981863 chr17:46018909-46018910(+) m6A 5'UTR       24981863 chr17:46018986-46018987(+) m6A 5'UTR//intron       24981863 chr17:46018996-46018997(+) m6A 5'UTR//intron       24981863 chr17:46019138-46019139(+) m6A CDS//intron       24981863 chr17:46019145-46019146(+) m6A CDS//intron       24981863 chr17:46019171-46019172(+) m6A CDS//intron       24981863 chr17:46024028-46024029(+) m6A 3'UTR//CDS//exon       24284625 chr17:46024119-46024120(+) m6A 3'UTR//CDS//exon       24284625//24981863 chr17:46024135-46024136(+) m6A 3'UTR//CDS//exon       24284625//24981863 chr17:46024155-46024156(+) m6A 3'UTR//exon       24284625//24981863 chr17:46024212-46024213(+) m6A 3'UTR//exon       24284625//24981863 chr17:46024232-46024233(+) m6A 3'UTR//exon       24284625 chr17:46024269-46024270(+) m6A 3'UTR       24284625 chr17:46024757-46024758(+) m6A 3'UTR       24981863 chr17:46024867-46024868(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PNPO	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-9-5p
Interactor2: PNPO

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg