Detail Information

Basic Information:


  VIRBase ID:  

VHID00428829

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-11-3p:           MOCS2:      

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Interactor Information:


Interactor1 Interactor2
Symbol kshv-miR-K12-11-3p MOCS2
miRBase
Accession/Entrez ID		 MIMAT0002181 4338
Organism Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV) Homo sapiens
Category miRNA mRNA
Alias - MCBPE//MOCO1//MOCODB//MPTS

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MOCS2
chr5:52398558(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MOCS2
chr5:52391529-52391530(-) m6A 3'UTR       27773535
chr5:52391542-52391543(-) m6A 3'UTR       27773535
chr5:52393415-52393416(-) m6A 3'UTR       27773535
chr5:52393915-52393916(-) m6A 3'UTR//exon       27773535
chr5:52393921-52393922(-) m6A 3'UTR//exon       27773535
chr5:52393967-52393968(-) m6A 3'UTR//exon       27773535
chr5:52393996-52393997(-) m6A 3'UTR//exon       27773535
chr5:52394174-52394175(-) m6A 3'UTR//exon       24981863//26404942//27773535
chr5:52394226-52394227(-) m6A 3'UTR//exon       24981863//27773535
chr5:52394244-52394245(-) m6A 3'UTR//exon       24981863//27773535
chr5:52394308-52394309(-) m6A 3'UTR//exon       24981863//27773535
chr5:52394390-52394391(-) m6A 3'UTR//exon       27773535
chr5:52405166-52405167(-) m6A 5'UTR//intron       24981863
chr5:52405284-52405285(-) m6A 5'UTR//intron       24981863
chr5:52405314-52405315(-) m6A 5'UTR//intron       24981863//27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate MOCS2
Exosome Blood     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: kshv-miR-K12-11-3p
Interactor2: MOCS2

Evidence Support:


Weak-Evidence PAR-CLIP
Prediction-Evidence PARalyzer
Support Database ViRBase

References:


PMID 22100165 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line BC-1 cells//BJAB cells Interactor2 expression Downregulation
Description Table S10F Genes that contribute to the enrichments of PAR-CLIP targets of miR-K11 from BC-3 libraries in downregulated mRNAs in BJAB/miR-K11 cells.

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