Basic Information:

  VIRBase ID:  

VHID00428464

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-11-3p:  MIMAT0002181          CPS1:  NR_163592     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-11-3p	CPS1
miRBase Accession/Entrez ID	MIMAT0002181	1373
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CPSASE1//PHN

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CPS1	chr2:211385082(+) A-I      intronic chr2:211429531(+) A-I      intronic chr2:211429622(+) A-I      intronic chr2:211529120(+) A-I      intronic chr2:211510335(+) A-I      intronic chr2:211539142(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CPS1	chr2:211421293-211421294(+) m6A 5'UTR//intron       24981863 chr2:211421348-211421349(+) m6A 5'UTR//intron       24284625//24981863//26404942 chr2:211444459-211444460(+) m6A CDS//exon       22575960 chr2:211444480-211444481(+) Tm CDS//exon       - chr2:211447402-211447403(+) m6A CDS       22575960 chr2:211452806-211452807(+) m6A CDS       22575960 chr2:211452830-211452831(+) m6A CDS       22575960 chr2:211452845-211452846(+) m6A CDS       22575960 chr2:211454860-211454861(+) m6A CDS       22575960 chr2:211454909-211454910(+) m6A CDS       22575960 chr2:211454917-211454918(+) m6A CDS       22575960 chr2:211454933-211454934(+) m6A CDS       22575960 chr2:211456631-211456632(+) m6A CDS       22575960 chr2:211456656-211456657(+) m6A CDS       22575960 chr2:211456684-211456685(+) m6A CDS       22575960 chr2:211457622-211457623(+) m6A CDS       22575960 chr2:211457672-211457673(+) m6A CDS       22575960 chr2:211464232-211464233(+) m6A CDS       22575960 chr2:211464269-211464270(+) m6A CDS       22575960 chr2:211464279-211464280(+) m6A CDS       22575960 chr2:211465285-211465286(+) m6A CDS       22575960 chr2:211465302-211465303(+) Tm CDS       - chr2:211465334-211465335(+) m6A CDS       22575960 chr2:211465365-211465366(+) m6A CDS       22575960 chr2:211465387-211465388(+) m6A CDS       22575960 chr2:211466950-211466951(+) m6A CDS       22575960 chr2:211470193-211470194(+) Am intron       - chr2:211473270-211473271(+) Am CDS       - chr2:211476958-211476959(+) Tm CDS       - chr2:211517185-211517186(+) Am intron       - chr2:211518815-211518816(+) Am CDS       - chr2:211521271-211521272(+) m6A CDS       22575960 chr2:211521293-211521294(+) Cm CDS       - chr2:211521329-211521330(+) m6A CDS       22575960 chr2:211525341-211525342(+) m6A CDS//exon       26404942 chr2:211532929-211532930(+) Y CDS       26075521 chr2:211539660-211539661(+) m6A CDS//exon       22575960 chr2:211540476-211540477(+) m6A CDS//exon       22575960 chr2:211542717-211542718(+) m6A 3'UTR//exon       24981863//26404942 chr2:211542768-211542769(+) m6A 3'UTR//exon       24981863 chr2:211542809-211542810(+) m6A 3'UTR//exon       24981863 chr2:211543435-211543436(+) m6A 3'UTR//exon       22575960 chr2:211543482-211543483(+) m6A 3'UTR//exon       22575960 chr2:211543502-211543503(+) m6A 3'UTR//exon       22575960

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CPS1	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-11-3p
Interactor2: CPS1

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg