Basic Information:

  VIRBase ID:  

VHID00425948

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-10b:  MIMAT0002180          ENO1:  NM_001428     

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Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-10b	ENO1
miRBase Accession/Entrez ID	MIMAT0002180	2023
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ENO1L1//HEL-S-17//MPB1//NNE//PPH

RNA Editing:

Resource	Symbol	Editing Position
Lncediting	ENO1	chr1: 8937747     chr1: 8937723     chr1: 8937812     chr1: 8935925     chr1: 8937925     chr1: 8937834     chr1: 8937749

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ENO1	chr1:8929801(-) A-I      intronic chr1:8934387(-) A-I      intronic chr1:8929827(-) A-I      intronic chr1:8929795(-) A-I      intronic chr1:8928893(-) A-I      intronic chr1:8934211(-) A-I      intronic chr1:8937557(-) A-I      intronic chr1:8936980(-) A-I      intronic chr1:8937319(-) A-I      intronic chr1:8937383(-) A-I      intronic chr1:8936970(-) A-I      intronic chr1:8927622(-) A-I      intronic chr1:8937426(-) A-I      intronic chr1:8936700(-) A-I      intronic chr1:8934451(-) A-I      intronic chr1:8932497(-) A-I      intronic chr1:8937353(-) A-I      intronic chr1:8934456(-) A-I      intronic chr1:8932580(-) A-I      intronic chr1:8932509(-) A-I      intronic chr1:8932709(-) A-I      intronic chr1:8932534(-) A-I      intronic chr1:8937425(-) A-I      intronic chr1:8932619(-) A-I      intronic chr1:8929036(-) A-I      intronic chr1:8936969(-) A-I      intronic chr1:8923767(-) A-I      intronic chr1:8937349(-) A-I      intronic chr1:8936712(-) A-I      intronic chr1:8932723(-) A-I      intronic chr1:8937023(-) A-I      intronic chr1:8937022(-) A-I      intronic chr1:8936810(-) A-I      intronic chr1:8936971(-) A-I      intronic chr1:8936972(-) A-I      intronic chr1:8932618(-) A-I      intronic chr1:8936931(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ENO1	chr1:8922185(-) G-A intron -    22484847 chr1:8922295(-) T-C intron -    22484847 chr1:8926782(-) A-C intron -    22484847 chr1:8927623(-) G-A intron -    22484847 chr1:8928909(-) A-T intron -    22484847 chr1:8934660(-) C-T intron -    22484847 chr1:8936972(-) A-G intron -    22484847 chr1:8937279(-) T-G intron -    22484847 chr1:8937325(-) G-A intron -    22484847 chr1:8937349(-) A-G intron -    22484847 chr1:8937353(-) A-G intron -    22484847 chr1:8937425(-) A-G intron -    22484847 chr1:8937812(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ENO1	chr1:8921265-8921266(-) m6A 3'UTR//exon       26404942//22575960 chr1:8921374-8921375(-) m6A 3'UTR//exon       26404942//27773535//22575960 chr1:8921434-8921435(-) m6A CDS//exon       26404942//27773535//22575960 chr1:8921443-8921444(-) m6A CDS//exon       26404942//27773535//22575960 chr1:8922997-8922998(-) m6A CDS//exon       26404942//27773535//22575960 chr1:8923295-8923296(-) Cm CDS//exon       - chr1:8923343-8923344(-) m6A CDS//exon       26404942//27773535//22575960 chr1:8925351-8925352(-) m6A CDS//exon       26404942//22575960 chr1:8925429-8925430(-) m6A CDS//exon       26404942//22575960 chr1:8925452-8925453(-) Cm CDS//exon       - chr1:8925523-8925524(-) m6A CDS//exon       26404942//22575960 chr1:8926474-8926475(-) m6A CDS//exon       26404942//22575960 chr1:8928058-8928059(-) m6A CDS//exon       26404942//22575960 chr1:8928070-8928071(-) Gm CDS//exon       - chr1:8928080-8928081(-) m6A CDS//exon       26404942//22575960 chr1:8928098-8928099(-) m6A CDS//exon       26404942//22575960 chr1:8928113-8928114(-) m6A CDS//exon       26404942//22575960 chr1:8930248-8930249(-) m6A exon//intron       26404942//22575960 chr1:8930291-8930292(-) m6A exon//intron       26404942//22575960 chr1:8930375-8930376(-) m6A exon//intron       22575960 chr1:8930536-8930537(-) m6A CDS//exon//intron       26404942//22575960 chr1:8931936-8931937(-) m6A exon//intron       26404942//22575960 chr1:8931967-8931968(-) m6A CDS//exon       24284625//26404942//22575960 chr1:8931978-8931979(-) m6A CDS//exon       24284625//26404942//22575960 chr1:8938060-8938061(-) m6A intron       24981863 chr1:8938351-8938352(-) Am intron       - chr1:8938650-8938651(-) m6A 5'UTR//exon       24284625//25456834//24981863//28052920//26404942//27773535//27371828//22575960 chr1:8938719-8938720(-) Gm 5'UTR//exon       - chr1:8938746-8938747(-) m6A 5'UTR//exon       24284625//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960 chr1:8939116-8939117(-) m6A 5'UTR       25456834//24981863//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ENO1	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Insoluble cytoplasm K562 cells     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-10b
Interactor2: ENO1

Evidence Support:

Prediction-Evidence	cRep//miRanda
Support Database	RepTar//VmiReg