Basic Information:

  VIRBase ID:  

VHID00423389

  Virus:  

Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6055

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      kshv-miR-K12-10a-3p:  MIMAT0002179          IGF1R:  NM_000875     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	kshv-miR-K12-10a-3p	IGF1R
miRBase Accession/Entrez ID	MIMAT0002179	3480
Organism	Human gammaherpesvirus 8 (Kaposi's sarcoma herpesvirus, KSHV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CD221//IGFIR//IGFR//JTK13

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	IGF1R	chr15:99233451(+) A-I      intronic chr15:99208456(+) A-I      intronic chr15:99207718(+) A-I      intronic chr15:99199703(+) A-I      intronic chr15:99199658(+) A-I      intronic chr15:99199622(+) A-I      intronic chr15:99199593(+) A-I      intronic chr15:99199559(+) A-I      intronic chr15:99199523(+) A-I      intronic chr15:99199161(+) A-I      intronic chr15:99199076(+) A-I      intronic chr15:99199074(+) A-I      intronic chr15:99199064(+) A-I      intronic chr15:99199041(+) A-I      intronic chr15:99296400(+) A-I      intronic chr15:99350128(+) A-I      intronic chr15:99330521(+) A-I      intronic chr15:99380568(+) A-I      intronic chr15:99246091(+) A-I      intronic chr15:99294449(+) A-I      intronic chr15:99294240(+) A-I      intronic chr15:99422064(+) A-I      intronic chr15:99422063(+) A-I      intronic chr15:99255939(+) A-I      intronic chr15:99382369(+) A-I      intronic chr15:99233406(+) A-I      intronic chr15:99233414(+) A-I      intronic chr15:99382376(+) A-I      intronic chr15:99382432(+) A-I      intronic chr15:99382477(+) A-I      intronic chr15:99382513(+) A-I      intronic chr15:99233429(+) A-I      intronic chr15:99384601(+) A-I      intronic chr15:99298868(+) A-I      intronic chr15:99298819(+) A-I      intronic chr15:99233465(+) A-I      intronic chr15:99412739(+) A-I      intronic chr15:99298814(+) A-I      intronic chr15:99298793(+) A-I      intronic chr15:99298791(+) A-I      intronic chr15:99412720(+) A-I      intronic chr15:99298786(+) A-I      intronic chr15:99384610(+) A-I      intronic chr15:99384611(+) A-I      intronic chr15:99233433(+) A-I      intronic chr15:99233461(+) A-I      intronic chr15:99472085(+) A-I      intronic chr15:99448534(+) A-I      intronic chr15:99386207(+) A-I      intronic chr15:99370350(+) A-I      intronic chr15:99296343(+) A-I      intronic chr15:99331863(+) A-I      intronic chr15:99363737(+) A-I      intronic chr15:99334355(+) A-I      intronic chr15:99506424(+) A-I      3'UTR chr15:99504395(+) A-I      3'UTR chr15:99422068(+) A-I      intronic chr15:99346955(+) A-I      intronic chr15:99295791(+) A-I      intronic chr15:99228435(+) A-I      intronic chr15:99295731(+) A-I      intronic chr15:99424619(+) A-I      intronic chr15:99298794(+) A-I      intronic chr15:99422177(+) A-I      intronic chr15:99233497(+) A-I      intronic chr15:99323609(+) A-I      intronic chr15:99323684(+) A-I      intronic chr15:99422176(+) A-I      intronic chr15:99422190(+) A-I      intronic chr15:99422015(+) A-I      intronic chr15:99296229(+) A-I      intronic chr15:99233498(+) A-I      intronic chr15:99298724(+) A-I      intronic chr15:99298738(+) A-I      intronic chr15:99298763(+) A-I      intronic chr15:99298774(+) A-I      intronic chr15:99421988(+) A-I      intronic chr15:99421948(+) A-I      intronic chr15:99407350(+) A-I      intronic chr15:99216298(+) A-I      intronic chr15:99199655(+) A-I      intronic chr15:99298889(+) A-I      intronic chr15:99298817(+) A-I      intronic chr15:99298893(+) A-I      intronic chr15:99346935(+) A-I      intronic chr15:99298936(+) A-I      intronic chr15:99306196(+) A-I      intronic chr15:99323578(+) A-I      intronic chr15:99296265(+) A-I      intronic chr15:99422005(+) A-I      intronic chr15:99298823(+) A-I      intronic chr15:99298715(+) A-I      intronic chr15:99311588(+) A-I      intronic chr15:99323565(+) A-I      intronic chr15:99256061(+) A-I      intronic chr15:99296730(+) A-I      intronic chr15:99300493(+) A-I      intronic chr15:99298816(+) A-I      intronic chr15:99323629(+) A-I      intronic chr15:99407404(+) A-I      intronic chr15:99254120(+) A-I      intronic chr15:99407223(+) A-I      intronic chr15:99379669(+) A-I      intronic chr15:99199157(+) A-I      intronic chr15:99308638(+) A-I      intronic chr15:99422078(+) A-I      intronic chr15:99298935(+) A-I      intronic chr15:99354275(+) A-I      intronic chr15:99208442(+) A-I      intronic chr15:99294157(+) A-I      intronic chr15:99311733(+) A-I      intronic chr15:99390264(+) A-I      intronic chr15:99294241(+) A-I      intronic chr15:99323524(+) A-I      intronic chr15:99355787(+) A-I      intronic chr15:99422010(+) A-I      intronic chr15:99355789(+) A-I      intronic chr15:99235412(+) A-I      intronic chr15:99207639(+) A-I      intronic chr15:99198999(+) A-I      intronic chr15:99233313(+) A-I      intronic chr15:99355634(+) A-I      intronic chr15:99407748(+) A-I      intronic chr15:99199116(+) A-I      intronic chr15:99235651(+) A-I      intronic chr15:99295745(+) A-I      intronic chr15:99355770(+) A-I      intronic chr15:99411513(+) A-I      intronic chr15:99472453(+) A-I      intronic chr15:99245958(+) A-I      intronic chr15:99355725(+) A-I      intronic chr15:99296684(+) A-I      intronic chr15:99254038(+) A-I      intronic chr15:99344796(+) A-I      intronic chr15:99355034(+) A-I      intronic chr15:99245597(+) A-I      intronic chr15:99371084(+) A-I      intronic chr15:99357680(+) A-I      intronic chr15:99294541(+) A-I      intronic chr15:99293890(+) A-I      intronic chr15:99295663(+) A-I      intronic chr15:99319676(+) A-I      intronic chr15:99355715(+) A-I      intronic chr15:99427808(+) A-I      intronic chr15:99207708(+) A-I      intronic chr15:99298755(+) A-I      intronic chr15:99298873(+) A-I      intronic chr15:99216179(+) A-I      intronic chr15:99475035(+) A-I      intronic chr15:99296294(+) A-I      intronic chr15:99208454(+) A-I      intronic chr15:99319677(+) A-I      intronic chr15:99234860(+) A-I      intronic chr15:99235463(+) A-I      intronic chr15:99298820(+) A-I      intronic chr15:99257663(+) A-I      intronic chr15:99256060(+) A-I      intronic chr15:99298750(+) A-I      intronic chr15:99400613(+) A-I      intronic chr15:99471965(+) A-I      intronic chr15:99293780(+) A-I      intronic chr15:99380554(+) A-I      intronic chr15:99354372(+) A-I      intronic chr15:99448570(+) A-I      intronic chr15:99499078(+) A-I      intronic chr15:99498501(+) A-I      intronic chr15:99235487(+) A-I      intronic chr15:99291625(+) A-I      intronic chr15:99281749(+) A-I      intronic chr15:99308827(+) A-I      intronic chr15:99354944(+) A-I      intronic chr15:99311894(+) A-I      intronic chr15:99407634(+) A-I      intronic chr15:99298805(+) A-I      intronic chr15:99438171(+) A-I      intronic chr15:99235406(+) A-I      intronic chr15:99306216(+) A-I      intronic chr15:99300559(+) A-I      intronic chr15:99199126(+) A-I      intronic chr15:99199631(+) A-I      intronic chr15:99422062(+) A-I      intronic chr15:99323593(+) A-I      intronic chr15:99296298(+) A-I      intronic chr15:99300422(+) A-I      intronic chr15:99298876(+) A-I      intronic chr15:99422070(+) A-I      intronic chr15:99300558(+) A-I      intronic chr15:99298854(+) A-I      intronic chr15:99246010(+) A-I      intronic chr15:99298706(+) A-I      intronic chr15:99323600(+) A-I      intronic chr15:99286146(+) A-I      intronic chr15:99216324(+) A-I      intronic chr15:99296724(+) A-I      intronic chr15:99421964(+) A-I      intronic chr15:99476604(+) A-I      intronic chr15:99472025(+) A-I      intronic chr15:99448770(+) A-I      intronic chr15:99448631(+) A-I      intronic chr15:99323764(+) A-I      intronic chr15:99298714(+) A-I      intronic chr15:99246075(+) A-I      intronic chr15:99472317(+) A-I      intronic chr15:99355686(+) A-I      intronic chr15:99449247(+) A-I      intronic chr15:99295693(+) A-I      intronic chr15:99298808(+) A-I      intronic chr15:99380721(+) A-I      intronic chr15:99296304(+) A-I      intronic chr15:99379628(+) A-I      intronic chr15:99199632(+) A-I      intronic chr15:99270048(+) A-I      intronic chr15:99257816(+) A-I      intronic chr15:99498488(+) A-I      intronic chr15:99295765(+) A-I      intronic chr15:99286110(+) A-I      intronic chr15:99199196(+) A-I      intronic chr15:99281500(+) A-I      intronic chr15:99298812(+) A-I      intronic chr15:99293781(+) A-I      intronic chr15:99298811(+) A-I      intronic chr15:99256044(+) A-I      intronic chr15:99407373(+) A-I      intronic chr15:99290456(+) A-I      intronic chr15:99319543(+) A-I      intronic chr15:99323728(+) A-I      intronic chr15:99296697(+) A-I      intronic chr15:99298760(+) A-I      intronic chr15:99281485(+) A-I      intronic chr15:99421966(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	IGF1R	chr15:99191894-99191895(+) Gm -       - chr15:99192340-99192341(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr15:99192360-99192361(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr15:99250847-99250848(+) m6A CDS//exon       24284625//24981863//26404942 chr15:99250901-99250902(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22608085 chr15:99250988-99250989(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99251025-99251026(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99251099-99251100(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99251162-99251163(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99251234-99251235(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99251248-99251249(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99251278-99251279(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99251314-99251315(+) m6A CDS//exon       24284625//25456834//24981863//26404942//22608085 chr15:99251321-99251322(+) m6A CDS//exon       24284625//25456834//24981863//26404942//22608085 chr15:99256404-99256405(+) Gm intron       - chr15:99277968-99277969(+) m6A exon//intron       24284625//24981863//26404942//22608085 chr15:99433921-99433922(+) m6A exon//intron       24981863 chr15:99433940-99433941(+) m6A exon//intron       24981863 chr15:99434592-99434593(+) m6A 5'UTR//CDS//exon       24284625//24981863 chr15:99434745-99434746(+) m6A 5'UTR//CDS//exon       24284625 chr15:99440043-99440044(+) m6A CDS//exon       - chr15:99440049-99440050(+) m6A CDS//exon       - chr15:99442729-99442730(+) m6A CDS//exon       24284625 chr15:99442813-99442814(+) m6A CDS//exon       24284625 chr15:99443878-99443879(+) m6A exon//intron       24284625 chr15:99443895-99443896(+) m6A exon//intron       24284625 chr15:99443946-99443947(+) m6A exon//intron       24284625 chr15:99451945-99451946(+) m6A CDS//exon       24284625//24981863//26404942 chr15:99451963-99451964(+) m6A CDS//exon       24284625//24981863//26404942 chr15:99451969-99451970(+) m6A CDS//exon       24284625//24981863//26404942 chr15:99452067-99452068(+) m6A CDS//exon       24284625//24981863//26404942 chr15:99452092-99452093(+) m6A CDS//exon       24284625//24981863//26404942 chr15:99452098-99452099(+) m6A CDS//exon       24284625//24981863//26404942 chr15:99452107-99452108(+) m6A CDS//exon       24284625//24981863//26404942 chr15:99456331-99456332(+) m6A CDS//exon       24284625//26404942 chr15:99456346-99456347(+) m6A CDS//exon       26404942 chr15:99459900-99459901(+) m6A CDS//exon       24284625//24981863//26404942 chr15:99459960-99459961(+) m6A 3'UTR//CDS//exon       24284625//24981863//26404942 chr15:99459968-99459969(+) m6A 3'UTR//CDS//exon       24284625//24981863//26404942 chr15:99460016-99460017(+) m6A 3'UTR//CDS//exon       24284625//24981863//26404942 chr15:99460138-99460139(+) m6A exon//intron       - chr15:99465441-99465442(+) m6A 3'UTR//CDS//exon       26404942 chr15:99465456-99465457(+) m6A 3'UTR//CDS//exon       26404942 chr15:99465491-99465492(+) m6A CDS//exon       26404942 chr15:99465536-99465537(+) m6A CDS//exon       26404942 chr15:99467155-99467156(+) m6A CDS//exon       26404942 chr15:99467180-99467181(+) m6A CDS//exon       26404942 chr15:99467776-99467777(+) m6A CDS//exon       26404942 chr15:99467811-99467812(+) m6A CDS//exon       26404942 chr15:99467820-99467821(+) m6A CDS//exon       26404942 chr15:99467829-99467830(+) m6A CDS//exon       26404942 chr15:99473507-99473508(+) m6A CDS       22575960 chr15:99478107-99478108(+) m6A CDS//intron       26404942//22575960 chr15:99478170-99478171(+) m6A CDS//intron       26404942 chr15:99478177-99478178(+) m6A CDS//intron       26404942 chr15:99478195-99478196(+) m6A CDS//intron       26404942 chr15:99482535-99482536(+) m6A CDS       26404942 chr15:99486180-99486181(+) m6A CDS       26404942 chr15:99497104-99497105(+) Cm intron       - chr15:99500295-99500296(+) m6A CDS//exon       24284625 chr15:99500420-99500421(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99500447-99500448(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99500458-99500459(+) Gm CDS//exon       - chr15:99500462-99500463(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99500483-99500484(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99500523-99500524(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99500532-99500533(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99500595-99500596(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99500695-99500696(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99500789-99500790(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr15:99500812-99500813(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr15:99500831-99500832(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr15:99500888-99500889(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085 chr15:99500915-99500916(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085 chr15:99500955-99500956(+) m6A 3'UTR       24284625//24209618//24981863//26404942 chr15:99501146-99501147(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085 chr15:99501193-99501194(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085 chr15:99501271-99501272(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99501354-99501355(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99501458-99501459(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99501463-99501464(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99501505-99501506(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99501588-99501589(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99501658-99501659(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99501684-99501685(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085 chr15:99501729-99501730(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085 chr15:99501810-99501811(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr15:99501842-99501843(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr15:99501850-99501851(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22608085 chr15:99501986-99501987(+) m6A 3'UTR       24284625 chr15:99502028-99502029(+) m6A 3'UTR       24284625 chr15:99502111-99502112(+) m6A 3'UTR       24284625 chr15:99502948-99502949(+) m6A 3'UTR       26404942 chr15:99503281-99503282(+) m6A 3'UTR       26404942 chr15:99503323-99503324(+) m6A 3'UTR       26404942 chr15:99503991-99503992(+) m6A 3'UTR       24284625 chr15:99504068-99504069(+) m6A 3'UTR       24284625 chr15:99504083-99504084(+) m6A 3'UTR       24284625 chr15:99504185-99504186(+) m6A 3'UTR       24284625 chr15:99504353-99504354(+) m6A 3'UTR       24284625//24981863//26404942 chr15:99504522-99504523(+) m6A 3'UTR       24284625 chr15:99504583-99504584(+) m6A 3'UTR       24284625 chr15:99504624-99504625(+) m6A 3'UTR       24284625//24981863 chr15:99504644-99504645(+) m6A 3'UTR       24284625//24981863 chr15:99504679-99504680(+) m6A 3'UTR       24284625//24981863 chr15:99504860-99504861(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99504953-99504954(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99504963-99504964(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99504974-99504975(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99504980-99504981(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99505059-99505060(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99505169-99505170(+) m6A 3'UTR       24284625//25456834//24981863//26404942//22608085 chr15:99505455-99505456(+) m6A 3'UTR       24284625 chr15:99505619-99505620(+) m6A 3'UTR       24284625//24209618//24981863//26404942//22608085 chr15:99505641-99505642(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085 chr15:99505655-99505656(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085 chr15:99505700-99505701(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99505724-99505725(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99505729-99505730(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99505760-99505761(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99505767-99505768(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99505873-99505874(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085 chr15:99505957-99505958(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085 chr15:99505982-99505983(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085 chr15:99506033-99506034(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085 chr15:99506054-99506055(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99506087-99506088(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99506093-99506094(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr15:99506156-99506157(+) m6A 3'UTR       24284625//25456834//24981863//26404942 chr15:99506695-99506696(+) Cm 3'UTR       - chr15:99506818-99506819(+) m6A 3'UTR       24284625//24981863//26404942 chr15:99506828-99506829(+) m6A 3'UTR       24284625//24981863//26404942 chr15:99506961-99506962(+) m6A 3'UTR       24284625//24981863//26404942 chr15:99506972-99506973(+) m6A 3'UTR       24284625//24981863//26404942 chr15:99506994-99506995(+) m6A 3'UTR       24284625//24981863//26404942 chr15:99507041-99507042(+) m6A 3'UTR       24284625//24981863//26404942 chr15:99507147-99507148(+) m6A 3'UTR       26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	IGF1R	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol HCC cell line (HepG2)|HeLa-S3 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):

Interactor1: kshv-miR-K12-10a-3p
Interactor2: IGF1R

Evidence Support:

Weak-Evidence	PAR-CLIP
Prediction-Evidence	cRep//miRanda//PARalyzer//Rep//Targetscan
Support Database	RepTar//ViRBase//VmiReg

References:

PMID	22100165	Target region	3'UTR
Source	RepTar//ViRBase//VmiReg	Interactor1 expression	None
Tissue or cell line	BC-3 cells	Interactor2 expression	None
Description	Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites.Clusters with seed matches to expressed miRNAs were considered candidate target sites. Of the clusters mapping to human 3'UTRs, 69% (BC-1) and 70% (BC-3) had seed matches to expressed miRNAs (Tables S6).Table S6B BC-3 derived 3'UTR clusters with seed matches to expressed miRNAs.