Basic Information:

  VIRBase ID:  

VHID00420997

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART22:  MIMAT0010132          PLEKHA1:  NM_001377247     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART22	PLEKHA1
miRBase Accession/Entrez ID	MIMAT0010132	59338
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	TAPP1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PLEKHA1	chr10:124190740(+) A-I      3'UTR chr10:124190738(+) A-I      3'UTR chr10:124190737(+) A-I      3'UTR chr10:124190766(+) A-I      3'UTR chr10:124190776(+) A-I      3'UTR chr10:124190770(+) A-I      3'UTR chr10:124166494(+) A-I      intronic chr10:124177085(+) A-I      intronic chr10:124144365(+) A-I      intronic chr10:124159300(+) A-I      intronic chr10:124159286(+) A-I      intronic chr10:124144938(+) A-I      intronic chr10:124144374(+) A-I      intronic chr10:124142905(+) A-I      intronic chr10:124144999(+) A-I      intronic chr10:124144937(+) A-I      intronic chr10:124144311(+) A-I      intronic chr10:124179534(+) A-I      ncRNA chr10:124185117(+) A-I      ncRNA chr10:124144075(+) A-I      intronic chr10:124144951(+) A-I      intronic chr10:124145015(+) A-I      intronic chr10:124144392(+) A-I      intronic chr10:124144305(+) A-I      intronic chr10:124144998(+) A-I      intronic chr10:124142872(+) A-I      intronic chr10:124144259(+) A-I      intronic chr10:124142899(+) A-I      intronic chr10:124144973(+) A-I      intronic chr10:124138141(+) A-I      intronic chr10:124144978(+) A-I      intronic chr10:124144352(+) A-I      intronic chr10:124144934(+) A-I      intronic chr10:124144207(+) A-I      intronic chr10:124142975(+) A-I      intronic chr10:124144384(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PLEKHA1	chr10:124175460-124175461(+) m6A CDS//exon       27773535 chr10:124189168-124189169(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22608085 chr10:124189302-124189303(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr10:124189316-124189317(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr10:124189333-124189334(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr10:124189354-124189355(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr10:124189369-124189370(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr10:124189416-124189417(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr10:124189596-124189597(+) m6A 3'UTR       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PLEKHA1	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART22
Interactor2: PLEKHA1

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg