Basic Information:

  VIRBase ID:  

VHID00419641

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART22:  MIMAT0010132          TAB2:  NR_125861     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART22	TAB2
miRBase Accession/Entrez ID	MIMAT0010132	23118
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CHTD2//MAP3K7IP2//TAB-2

RNA Editing:

Resource	Symbol	Editing Position
Lncediting	TAB2	chr6: 149542018     chr6: 149541962

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TAB2	chr6:149670452(+) A-I      intronic chr6:149717344(+) A-I      intronic chr6:149718306(+) A-I      intronic chr6:149718344(+) A-I      intronic chr6:149670445(+) A-I      intronic chr6:149670462(+) A-I      intronic chr6:149670468(+) A-I      intronic chr6:149670481(+) A-I      intronic chr6:149655614(+) A-I      intronic chr6:149671123(+) A-I      intronic chr6:149671148(+) A-I      intronic chr6:149671197(+) A-I      intronic chr6:149671251(+) A-I      intronic chr6:149671350(+) A-I      intronic chr6:149676546(+) A-I      intronic chr6:149676547(+) A-I      intronic chr6:149676552(+) A-I      intronic chr6:149676642(+) A-I      intronic chr6:149676707(+) A-I      intronic chr6:149676714(+) A-I      intronic chr6:149678396(+) A-I      intronic chr6:149678437(+) A-I      intronic chr6:149678467(+) A-I      intronic chr6:149678892(+) A-I      intronic chr6:149678953(+) A-I      intronic chr6:149704893(+) A-I      intronic chr6:149717271(+) A-I      intronic chr6:149679011(+) A-I      intronic chr6:149679080(+) A-I      intronic chr6:149702107(+) A-I      intronic chr6:149702123(+) A-I      intronic chr6:149660352(+) A-I      intronic chr6:149660395(+) A-I      intronic chr6:149660405(+) A-I      intronic chr6:149660783(+) A-I      intronic chr6:149660814(+) A-I      intronic chr6:149660815(+) A-I      intronic chr6:149660834(+) A-I      intronic chr6:149660864(+) A-I      intronic chr6:149704864(+) A-I      intronic chr6:149704087(+) A-I      intronic chr6:149704848(+) A-I      intronic chr6:149702137(+) A-I      intronic chr6:149718498(+) A-I      intronic chr6:149669981(+) A-I      intronic chr6:149704980(+) A-I      intronic chr6:149706542(+) A-I      intronic chr6:149706552(+) A-I      intronic chr6:149706596(+) A-I      intronic chr6:149660871(+) A-I      intronic chr6:149660884(+) A-I      intronic chr6:149656629(+) A-I      intronic chr6:149702145(+) A-I      intronic chr6:149702163(+) A-I      intronic chr6:149702779(+) A-I      intronic chr6:149702789(+) A-I      intronic chr6:149702809(+) A-I      intronic chr6:149702810(+) A-I      intronic chr6:149669982(+) A-I      intronic chr6:149710155(+) A-I      intronic chr6:149710257(+) A-I      intronic chr6:149702854(+) A-I      intronic chr6:149656693(+) A-I      intronic chr6:149704928(+) A-I      intronic chr6:149710352(+) A-I      intronic chr6:149669924(+) A-I      intronic chr6:149670399(+) A-I      intronic chr6:149669919(+) A-I      intronic chr6:149702946(+) A-I      intronic chr6:149703571(+) A-I      intronic chr6:149703572(+) A-I      intronic chr6:149703574(+) A-I      intronic chr6:149710660(+) A-I      intronic chr6:149710661(+) A-I      intronic chr6:149710687(+) A-I      intronic chr6:149710786(+) A-I      intronic chr6:149710790(+) A-I      intronic chr6:149669295(+) A-I      intronic chr6:149669279(+) A-I      intronic chr6:149661001(+) A-I      intronic chr6:149660991(+) A-I      intronic chr6:149660982(+) A-I      intronic chr6:149703626(+) A-I      intronic chr6:149660892(+) A-I      intronic chr6:149656526(+) A-I      intronic chr6:149710504(+) A-I      intronic chr6:149710526(+) A-I      intronic chr6:149710543(+) A-I      intronic chr6:149710654(+) A-I      intronic chr6:149704819(+) A-I      intronic chr6:149704793(+) A-I      intronic chr6:149656542(+) A-I      intronic chr6:149669328(+) A-I      intronic chr6:149655561(+) A-I      intronic chr6:149641456(+) A-I      intronic chr6:149641410(+) A-I      intronic chr6:149702850(+) A-I      intronic chr6:149670436(+) A-I      intronic chr6:149704746(+) A-I      intronic chr6:149656699(+) A-I      5'UTR chr6:149656732(+) A-I      5'UTR chr6:149660388(+) A-I      intronic chr6:149660338(+) A-I      intronic chr6:149660935(+) A-I      intronic chr6:149704860(+) A-I      intronic chr6:149660368(+) A-I      intronic chr6:149655560(+) A-I      intronic chr6:149676758(+) A-I      intronic chr6:149655707(+) A-I      intronic chr6:149676638(+) A-I      intronic chr6:149671257(+) A-I      intronic chr6:149702144(+) A-I      intronic chr6:149710266(+) A-I      intronic chr6:149656572(+) A-I      intronic chr6:149667872(+) A-I      intronic chr6:149701282(+) A-I      intronic chr6:149710351(+) A-I      intronic chr6:149671289(+) A-I      intronic chr6:149660337(+) A-I      intronic chr6:149710191(+) A-I      intronic chr6:149702146(+) A-I      intronic chr6:149702983(+) A-I      intronic chr6:149704822(+) A-I      intronic chr6:149702168(+) A-I      intronic chr6:149704248(+) A-I      intronic chr6:149656567(+) A-I      intronic chr6:149704788(+) A-I      intronic chr6:149702961(+) A-I      intronic chr6:149718457(+) A-I      intronic chr6:149669422(+) A-I      intronic chr6:149656534(+) A-I      intronic chr6:149704740(+) A-I      intronic chr6:149679020(+) A-I      intronic chr6:149655766(+) A-I      intronic chr6:149655793(+) A-I      intronic chr6:149704981(+) A-I      intronic chr6:149660341(+) A-I      intronic chr6:149710312(+) A-I      intronic chr6:149656724(+) A-I      5'UTR chr6:149670004(+) A-I      intronic chr6:149671268(+) A-I      intronic chr6:149704971(+) A-I      intronic chr6:149710275(+) A-I      intronic chr6:149660299(+) A-I      intronic chr6:149704140(+) A-I      intronic chr6:149669922(+) A-I      intronic chr6:149660890(+) A-I      intronic chr6:149671207(+) A-I      intronic chr6:149703478(+) A-I      intronic chr6:149671344(+) A-I      intronic chr6:149669327(+) A-I      intronic chr6:149704144(+) A-I      intronic chr6:149703460(+) A-I      intronic chr6:149678969(+) A-I      intronic chr6:149717337(+) A-I      intronic chr6:149670099(+) A-I      intronic chr6:149669398(+) A-I      intronic chr6:149678929(+) A-I      intronic chr6:149671288(+) A-I      intronic chr6:149710557(+) A-I      intronic chr6:149678936(+) A-I      intronic chr6:149704780(+) A-I      intronic chr6:149669319(+) A-I      intronic chr6:149678859(+) A-I      intronic chr6:149676641(+) A-I      intronic chr6:149703612(+) A-I      intronic chr6:149655692(+) A-I      intronic chr6:149702754(+) A-I      intronic chr6:149710797(+) A-I      intronic chr6:149676540(+) A-I      intronic chr6:149660835(+) A-I      intronic chr6:149660852(+) A-I      intronic chr6:149671330(+) A-I      intronic chr6:149670409(+) A-I      intronic chr6:149678304(+) A-I      intronic chr6:149678390(+) A-I      intronic chr6:149671315(+) A-I      intronic chr6:149676651(+) A-I      intronic chr6:149704139(+) A-I      intronic chr6:149671351(+) A-I      intronic chr6:149704858(+) A-I      intronic chr6:149704135(+) A-I      intronic chr6:149670369(+) A-I      intronic chr6:149660290(+) A-I      intronic chr6:149660861(+) A-I      intronic chr6:149655619(+) A-I      intronic chr6:149660339(+) A-I      intronic chr6:149660460(+) A-I      intronic chr6:149710185(+) A-I      intronic chr6:149710195(+) A-I      intronic chr6:149718527(+) A-I      intronic chr6:149660298(+) A-I      intronic chr6:149702848(+) A-I      intronic chr6:149704236(+) A-I      intronic chr6:149718588(+) A-I      intronic chr6:149671265(+) A-I      intronic chr6:149704777(+) A-I      intronic chr6:149660847(+) A-I      intronic chr6:149670498(+) A-I      intronic chr6:149669265(+) A-I      intronic chr6:149660874(+) A-I      intronic chr6:149679037(+) A-I      intronic chr6:149704141(+) A-I      intronic chr6:149660334(+) A-I      intronic chr6:149710328(+) A-I      intronic chr6:149671320(+) A-I      intronic chr6:149669875(+) A-I      intronic chr6:149678445(+) A-I      intronic chr6:149671828(+) A-I      intronic chr6:149669296(+) A-I      intronic chr6:149664522(+) A-I      intronic chr6:149702836(+) A-I      intronic chr6:149660446(+) A-I      intronic chr6:149655644(+) A-I      intronic chr6:149671868(+) A-I      intronic chr6:149701347(+) A-I      intronic chr6:149704086(+) A-I      intronic chr6:149660230(+) A-I      intronic chr6:149678502(+) A-I      intronic chr6:149669844(+) A-I      intronic chr6:149660945(+) A-I      intronic chr6:149660790(+) A-I      intronic chr6:149667646(+) A-I      ncRNA

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TAB2	chr6:149641271(+) A-G intron -    22484847 chr6:149646991(+) T-C intron -    22484847 chr6:149655619(+) A-G intron -    22484847 chr6:149655766(+) A-G intron -    22484847 chr6:149656534(+) A-G intron -    22484847 chr6:149656724(+) A-G exon 5'UTR    22484847 chr6:149656730(+) A-G exon 5'UTR    22484847 chr6:149660230(+) A-G intron -    22484847 chr6:149660242(+) C-A intron -    22484847 chr6:149660290(+) A-G intron -    22484847 chr6:149660298(+) A-G intron -    22484847 chr6:149660299(+) A-G intron -    22484847 chr6:149660305(+) T-G intron -    22484847 chr6:149660334(+) A-G intron -    22484847 chr6:149660337(+) A-G intron -    22484847 chr6:149660338(+) A-G intron -    22484847 chr6:149660339(+) A-G intron -    22484847 chr6:149660340(+) A-G intron -    22484847 chr6:149660341(+) A-G intron -    22484847 chr6:149660368(+) A-G intron -    22484847 chr6:149660388(+) A-G intron -    22484847 chr6:149660790(+) A-G intron -    22484847 chr6:149660835(+) A-G intron -    22484847 chr6:149660847(+) A-G intron -    22484847 chr6:149660852(+) A-G intron -    22484847 chr6:149660861(+) A-G intron -    22484847 chr6:149660874(+) A-G intron -    22484847 chr6:149660876(+) A-G intron -    22484847 chr6:149660890(+) A-G intron -    22484847 chr6:149660918(+) A-G intron -    22484847 chr6:149660935(+) A-G intron -    22484847 chr6:149660945(+) A-G intron -    22484847 chr6:149660955(+) A-G intron -    22484847 chr6:149660986(+) G-A intron -    22484847 chr6:149664522(+) A-G intron -    22484847 chr6:149669282(+) A-G intron -    22484847 chr6:149669302(+) G-A intron -    22484847 chr6:149669319(+) A-G intron -    22484847 chr6:149669327(+) A-G intron -    22484847 chr6:149669398(+) A-G intron -    22484847 chr6:149669422(+) A-G intron -    22484847 chr6:149669467(+) A-G intron -    22484847 chr6:149669922(+) A-G intron -    22484847 chr6:149670004(+) A-G intron -    22484847 chr6:149670307(+) A-G intron -    22484847 chr6:149670417(+) A-G intron -    22484847 chr6:149670427(+) G-A intron -    22484847 chr6:149670498(+) A-G intron -    22484847 chr6:149671132(+) A-G intron -    22484847 chr6:149671137(+) A-G intron -    22484847 chr6:149671167(+) A-G intron -    22484847 chr6:149671168(+) A-G intron -    22484847 chr6:149671185(+) A-G intron -    22484847 chr6:149671207(+) A-G intron -    22484847 chr6:149671233(+) A-G intron -    22484847 chr6:149671257(+) A-G intron -    22484847 chr6:149671265(+) A-G intron -    22484847 chr6:149671268(+) A-G intron -    22484847 chr6:149671288(+) A-G intron -    22484847 chr6:149671289(+) A-G intron -    22484847 chr6:149671315(+) A-G intron -    22484847 chr6:149671320(+) A-G intron -    22484847 chr6:149671330(+) A-G intron -    22484847 chr6:149671336(+) A-G intron -    22484847 chr6:149671344(+) A-G intron -    22484847 chr6:149671351(+) A-G intron -    22484847 chr6:149671820(+) A-G intron -    22484847 chr6:149671828(+) A-G intron -    22484847 chr6:149671868(+) A-G intron -    22484847 chr6:149678304(+) A-G intron -    22484847 chr6:149678381(+) A-G intron -    22484847 chr6:149678390(+) A-G intron -    22484847 chr6:149678445(+) A-G intron -    22484847 chr6:149678477(+) A-G intron -    22484847 chr6:149678502(+) A-G intron -    22484847 chr6:149678515(+) A-G intron -    22484847 chr6:149678859(+) A-G intron -    22484847 chr6:149678929(+) A-G intron -    22484847 chr6:149678936(+) A-G intron -    22484847 chr6:149678969(+) A-G intron -    22484847 chr6:149679017(+) A-G intron -    22484847 chr6:149679020(+) A-G intron -    22484847 chr6:149679037(+) A-G intron -    22484847 chr6:149701142(+) A-G intron -    22484847 chr6:149701269(+) A-G intron -    22484847 chr6:149702144(+) A-G intron -    22484847 chr6:149702146(+) A-G intron -    22484847 chr6:149702822(+) A-G intron -    22484847 chr6:149702961(+) A-G intron -    22484847 chr6:149703478(+) A-G intron -    22484847 chr6:149703612(+) A-G intron -    22484847 chr6:149703687(+) A-G intron -    22484847 chr6:149704086(+) A-G intron -    22484847 chr6:149704248(+) A-G intron -    22484847 chr6:149704314(+) G-A intron -    22484847 chr6:149704740(+) A-G intron -    22484847 chr6:149704777(+) A-G intron -    22484847 chr6:149704780(+) A-G intron -    22484847 chr6:149704788(+) A-G intron -    22484847 chr6:149704822(+) A-G intron -    22484847 chr6:149704836(+) A-G intron -    22484847 chr6:149704858(+) A-G intron -    22484847 chr6:149704860(+) A-G intron -    22484847 chr6:149706529(+) A-G intron -    22484847 chr6:149710185(+) A-G intron -    22484847 chr6:149710191(+) A-G intron -    22484847 chr6:149710192(+) A-G intron -    22484847 chr6:149710195(+) A-G intron -    22484847 chr6:149710196(+) A-G intron -    22484847 chr6:149710221(+) A-G intron -    22484847 chr6:149710258(+) A-G intron -    22484847 chr6:149710266(+) A-G intron -    22484847 chr6:149710275(+) A-G intron -    22484847 chr6:149710312(+) A-G intron -    22484847 chr6:149710328(+) A-G intron -    22484847 chr6:149710351(+) A-G intron -    22484847 chr6:149710527(+) A-G intron -    22484847 chr6:149710557(+) A-G intron -    22484847 chr6:149717227(+) T-C intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TAB2	chr6:149565037-149565038(+) m6A intron       - chr6:149565120-149565121(+) m6A intron       - chr6:149565146-149565147(+) m6A intron       - chr6:149565203-149565204(+) m6A intron       - chr6:149668328-149668329(+) m6A exon//intron       24981863 chr6:149691055-149691056(+) m6A 5'UTR//intron       24209618 chr6:149693528-149693529(+) m6A CDS//intron       24284625//24209618 chr6:149699226-149699227(+) m6A 5'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr6:149699292-149699293(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:149699307-149699308(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:149699354-149699355(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:149699380-149699381(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:149699410-149699411(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:149699432-149699433(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr6:149699540-149699541(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr6:149699561-149699562(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr6:149699609-149699610(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr6:149699735-149699736(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr6:149699778-149699779(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr6:149699819-149699820(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr6:149699888-149699889(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr6:149700010-149700011(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085 chr6:149700021-149700022(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085 chr6:149700037-149700038(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085 chr6:149700043-149700044(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085 chr6:149700070-149700071(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085 chr6:149700085-149700086(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085 chr6:149700092-149700093(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085 chr6:149700125-149700126(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085 chr6:149700132-149700133(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085 chr6:149700244-149700245(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085 chr6:149700285-149700286(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085 chr6:149700312-149700313(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085 chr6:149700508-149700509(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr6:149700548-149700549(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr6:149700573-149700574(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr6:149700608-149700609(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085 chr6:149700616-149700617(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085 chr6:149701273-149701274(+) m6A 3'UTR//intron       24981863 chr6:149718785-149718786(+) m6A 3'UTR//CDS       24981863 chr6:149718936-149718937(+) m6A exon//intron       24981863 chr6:149720312-149720313(+) m6A 3'UTR//CDS//exon       24284625//24209618//27773535//22608085 chr6:149721598-149721599(+) m6A intron       - chr6:149721638-149721639(+) m6A intron       24209618 chr6:149721652-149721653(+) m6A intron       24209618 chr6:149721673-149721674(+) m6A intron       24209618 chr6:149722162-149722163(+) Y intron       25219674 chr6:149730732-149730733(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085 chr6:149730741-149730742(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr6:149730748-149730749(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr6:149730802-149730803(+) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr6:149730827-149730828(+) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr6:149730882-149730883(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr6:149730903-149730904(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr6:149731075-149731076(+) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr6:149731252-149731253(+) m6A 3'UTR       24284625//24981863//26404942//22608085 chr6:149731276-149731277(+) m6A 3'UTR       24284625//24981863//26404942//22608085 chr6:149731297-149731298(+) m6A 3'UTR       24284625//24981863//26404942//22608085 chr6:149731335-149731336(+) m6A 3'UTR       24284625//24981863//26404942//22575960//22608085 chr6:149731759-149731760(+) m6A 3'UTR       22608085 chr6:149731885-149731886(+) m6A 3'UTR       22608085 chr6:149731914-149731915(+) m6A 3'UTR       22608085 chr6:149731953-149731954(+) m6A 3'UTR       22608085 chr6:149731994-149731995(+) m6A 3'UTR       22608085 chr6:149732111-149732112(+) m6A 3'UTR       24981863//26404942//27773535//22608085 chr6:149732132-149732133(+) m6A 3'UTR       24981863//26404942//27773535//22608085 chr6:149732159-149732160(+) m6A 3'UTR       24981863//26404942//27773535//22608085 chr6:149732167-149732168(+) m6A 3'UTR       24981863//26404942//27773535//22608085 chr6:149732173-149732174(+) m6A 3'UTR       24981863//26404942//27773535//22608085 chr6:149732275-149732276(+) m6A 3'UTR       24981863//26404942//27773535//22608085 chr6:149732294-149732295(+) m6A 3'UTR       24981863//26404942//27773535//22608085 chr6:149732376-149732377(+) m6A 3'UTR       24981863//26404942//27773535//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	TAB2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART22
Interactor2: TAB2

Evidence Support:

Weak-Evidence	PAR-CLIP
Prediction-Evidence	cRep//miRanda//PARalyzer//Targetscan
Support Database	RepTar//ViRBase//VIRmiRNA//VmiReg

References:

PMID	22100165	Target region	3'UTR
Source	RepTar//ViRBase//VIRmiRNA//VmiReg	Interactor1 expression	None
Tissue or cell line	BC-1 cells	Interactor2 expression	Downregulation
Description	Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites.Clusters with seed matches to expressed miRNAs were considered candidate target sites. Of the clusters mapping to human 3'UTRs, 69% (BC-1) and 70% (BC-3) had seed matches to expressed miRNAs (Tables S6).Table S6A BC-1 derived 3'UTR clusters with seed matches to expressed miRNAs.