Basic Information:

  VIRBase ID:  

VHID00411813

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART5-3p:  MIMAT0009205          ATG4B:  NM_178326     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART5-3p	ATG4B
miRBase Accession/Entrez ID	MIMAT0009205	23192
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	APG4B//AUTL1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ATG4B	chr2:242606872(+) A-I      intronic chr2:242606833(+) A-I      intronic chr2:242604361(+) A-I      intronic chr2:242604285(+) A-I      intronic chr2:242603814(+) A-I      intronic chr2:242603769(+) A-I      intronic chr2:242603493(+) A-I      intronic chr2:242603472(+) A-I      intronic chr2:242603391(+) A-I      intronic chr2:242606832(+) A-I      intronic chr2:242586267(+) A-I      intronic chr2:242586301(+) A-I      intronic chr2:242586327(+) A-I      intronic chr2:242586473(+) A-I      intronic chr2:242586885(+) A-I      intronic chr2:242603318(+) A-I      intronic chr2:242582377(+) A-I      intronic chr2:242602528(+) A-I      intronic chr2:242587524(+) A-I      intronic chr2:242583555(+) A-I      intronic chr2:242603364(+) A-I      intronic chr2:242603141(+) A-I      intronic chr2:242586382(+) A-I      intronic chr2:242587457(+) A-I      intronic chr2:242603354(+) A-I      intronic chr2:242604000(+) A-I      intronic chr2:242602636(+) A-I      intronic chr2:242603359(+) A-I      intronic chr2:242604140(+) A-I      intronic chr2:242603325(+) A-I      intronic chr2:242583552(+) A-I      intronic chr2:242587782(+) A-I      intronic chr2:242602509(+) A-I      intronic chr2:242584150(+) A-I      intronic chr2:242603842(+) A-I      intronic chr2:242603768(+) A-I      intronic chr2:242603390(+) A-I      intronic chr2:242583515(+) A-I      intronic chr2:242603400(+) A-I      intronic chr2:242586779(+) A-I      intronic chr2:242604123(+) A-I      intronic chr2:242586985(+) A-I      intronic chr2:242603689(+) A-I      intronic chr2:242603146(+) A-I      intronic chr2:242586249(+) A-I      intronic chr2:242603427(+) A-I      intronic chr2:242587418(+) A-I      intronic chr2:242603372(+) A-I      intronic chr2:242582398(+) A-I      intronic chr2:242602501(+) A-I      intronic chr2:242606930(+) A-I      intronic chr2:242609107(+) A-I      intronic chr2:242587408(+) A-I      intronic chr2:242603715(+) A-I      intronic chr2:242603729(+) A-I      intronic chr2:242603444(+) A-I      intronic chr2:242602441(+) A-I      intronic chr2:242587777(+) A-I      intronic chr2:242603140(+) A-I      intronic chr2:242586343(+) A-I      intronic chr2:242583580(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ATG4B	chr2:242591728(+) A-I intron -    21960545 chr2:242582367(+) A-G intron -    22484847 chr2:242582398(+) A-G intron -    22484847 chr2:242583515(+) A-G intron -    22484847 chr2:242586343(+) A-G intron -    22484847 chr2:242586985(+) A-G intron -    22484847 chr2:242596876(+) T-C intron -    22484847 chr2:242603124(+) A-G intron -    22484847 chr2:242603141(+) A-G intron -    22484847 chr2:242603354(+) A-G intron -    22484847 chr2:242603359(+) A-G intron -    22484847 chr2:242603364(+) A-G intron -    22484847 chr2:242603390(+) A-G intron -    22484847 chr2:242603761(+) A-G intron -    22484847 chr2:242603768(+) A-G intron -    22484847 chr2:242603799(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ATG4B	chr2:242577120-242577121(+) m6A 5'UTR//exon       24981863 chr2:242577721-242577722(+) m6A 5'UTR//intron       24981863 chr2:242590477-242590478(+) m6A 5'UTR//CDS//exon       - chr2:242590629-242590630(+) m6A exon//intron       - chr2:242590667-242590668(+) m6A exon//intron       - chr2:242590712-242590713(+) m6A 5'UTR//CDS//exon//intron       - chr2:242590735-242590736(+) m6A 5'UTR//CDS//exon//intron       - chr2:242591342-242591343(+) m6A CDS//exon//intron       - chr2:242599058-242599059(+) m6A exon//intron       22608085 chr2:242599093-242599094(+) m6A exon//intron       22608085 chr2:242608166-242608167(+) m6A exon//intron       - chr2:242608255-242608256(+) m6A exon//intron       - chr2:242610808-242610809(+) m6A 3'UTR//CDS//exon       24284625 chr2:242610961-242610962(+) m6A exon//intron       24284625 chr2:242611015-242611016(+) m6A exon//intron       24284625 chr2:242611103-242611104(+) m6A exon//intron       - chr2:242611108-242611109(+) m6A exon//intron       - chr2:242611146-242611147(+) m6A exon//intron       - chr2:242611185-242611186(+) m6A exon//intron       - chr2:242611194-242611195(+) m6A exon//intron       - chr2:242611289-242611290(+) m6A exon//intron       24284625 chr2:242611298-242611299(+) m6A exon//intron       24284625 chr2:242611317-242611318(+) m6A exon//intron       24284625 chr2:242611351-242611352(+) m6A exon//intron       24284625 chr2:242611656-242611657(+) m6A 3'UTR//CDS//exon       24284625//24209618 chr2:242611818-242611819(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr2:242611861-242611862(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr2:242612045-242612046(+) m6A 3'UTR//exon       24284625//25456834//22608085 chr2:242612051-242612052(+) m6A 3'UTR//exon       24284625//25456834//24981863//22608085 chr2:242612092-242612093(+) m6A 3'UTR//exon       24284625//25456834//24981863//22575960//22608085 chr2:242612149-242612150(+) m6A 3'UTR//exon       24284625//25456834//24981863//22575960//22608085 chr2:242612308-242612309(+) m6A 3'UTR//exon       24284625//25456834//24981863 chr2:242612330-242612331(+) m6A 3'UTR//exon       24284625//25456834//24981863 chr2:242612604-242612605(+) m6A 3'UTR//exon       24284625 chr2:242612636-242612637(+) m6A 3'UTR//exon       24284625 chr2:242612673-242612674(+) m6A 3'UTR//exon       24284625 chr2:242612807-242612808(+) m6A 3'UTR//exon       24284625 chr2:242612868-242612869(+) m6A 3'UTR//exon       24284625//25456834//24981863 chr2:242612933-242612934(+) m6A 3'UTR//exon       24284625//25456834//24981863 chr2:242612969-242612970(+) m6A 3'UTR//exon       24284625//25456834//24981863 chr2:242612996-242612997(+) m6A 3'UTR//exon       24284625//25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ATG4B	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART5-3p
Interactor2: ATG4B

Evidence Support:

Prediction-Evidence	miRanda//PITA//RNAHybrid//Targetscan
Support Database	VmiReg