Basic Information:

  VIRBase ID:  

VHID00410308

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART4-3p:  MIMAT0009204          CLEC7A:  NR_125336     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART4-3p	CLEC7A
miRBase Accession/Entrez ID	MIMAT0009204	64581
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	BGR//CANDF4//CD369//CLECSF12//DECTIN1//SCARE2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CLEC7A	chr12:10270690(-) A-I      3'UTR chr12:10270694(-) A-I      3'UTR chr12:10270693(-) A-I      3'UTR chr12:10275089(-) A-I      intronic chr12:10275293(-) A-I      intronic chr12:10280588(-) A-I      intronic chr12:10274507(-) A-I      intronic chr12:10273426(-) A-I      intronic chr12:10273357(-) A-I      intronic chr12:10275385(-) A-I      intronic chr12:10274495(-) A-I      intronic chr12:10273351(-) A-I      intronic chr12:10275084(-) A-I      intronic chr12:10273608(-) A-I      intronic chr12:10275209(-) A-I      intronic chr12:10270736(-) A-I      3'UTR chr12:10270556(-) A-I      3'UTR chr12:10270680(-) A-I      3'UTR chr12:10270608(-) A-I      3'UTR chr12:10280592(-) A-I      intronic chr12:10276104(-) A-I      intronic chr12:10273593(-) A-I      intronic chr12:10273592(-) A-I      intronic chr12:10273491(-) A-I      intronic chr12:10276102(-) A-I      intronic chr12:10282381(-) A-I      intronic chr12:10273555(-) A-I      intronic chr12:10273490(-) A-I      intronic chr12:10273459(-) A-I      intronic chr12:10273609(-) A-I      intronic chr12:10270795(-) A-I      3'UTR chr12:10270544(-) A-I      3'UTR chr12:10270742(-) A-I      3'UTR

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CLEC7A	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Exosome Blood     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART4-3p
Interactor2: CLEC7A

Evidence Support:

Weak-Evidence	PAR-CLIP
Prediction-Evidence	miRanda//PARalyzer//Targetscan
Support Database	ViRBase//VIRmiRNA//VmiReg

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase//VIRmiRNA//VmiReg	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).