Basic Information:

  VIRBase ID:  

VHID00408796

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART4-3p:  MIMAT0009204          PLCG1:  NM_002660     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART4-3p	PLCG1
miRBase Accession/Entrez ID	MIMAT0009204	5335
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	NCKAP3//PLC-II//PLC1//PLC148//PLCgamma1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PLCG1	chr20:39804196(+) A-I      3'UTR chr20:39768959(+) A-I      intronic chr20:39786821(+) A-I      intronic chr20:39781974(+) A-I      intronic chr20:39782144(+) A-I      intronic chr20:39782371(+) A-I      intronic chr20:39782070(+) A-I      intronic chr20:39800239(+) A-I      intronic chr20:39782416(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PLCG1	chr20:39766428-39766429(+) m6A CDS//exon       - chr20:39788283-39788284(+) m6A CDS//exon       - chr20:39788293-39788294(+) m6A CDS//exon       - chr20:39788314-39788315(+) m6A CDS//exon       - chr20:39788771-39788772(+) Tm CDS//exon       - chr20:39792574-39792575(+) m6A CDS//exon       - chr20:39792723-39792724(+) m6A CDS       - chr20:39793598-39793599(+) m6A CDS       - chr20:39793625-39793626(+) m6A CDS       - chr20:39793658-39793659(+) m6A CDS       - chr20:39794146-39794147(+) m6A CDS//exon       24284625//24981863 chr20:39794885-39794886(+) m6A CDS//exon       - chr20:39794907-39794908(+) m6A CDS//exon       - chr20:39795011-39795012(+) m6A CDS//exon       - chr20:39795208-39795209(+) m6A CDS//exon       - chr20:39795364-39795365(+) m6A CDS//exon       - chr20:39795380-39795381(+) m6A CDS//exon       - chr20:39795426-39795427(+) m6A CDS//exon       - chr20:39796315-39796316(+) m6A exon//intron       - chr20:39797729-39797730(+) m6A CDS//exon       24284625//24209618//24981863 chr20:39797765-39797766(+) m6A CDS//exon       24284625//24209618//24981863 chr20:39798109-39798110(+) m6A CDS//exon       24284625//24209618 chr20:39798124-39798125(+) m6A CDS//exon       24284625//24209618 chr20:39798862-39798863(+) m6A CDS//exon       - chr20:39798873-39798874(+) Am CDS//exon       - chr20:39798894-39798895(+) m6A CDS//exon       - chr20:39798925-39798926(+) m6A exon//intron       - chr20:39800928-39800929(+) Am CDS//intron       - chr20:39802896-39802897(+) m6A CDS//exon//intron       24284625//22608085 chr20:39802926-39802927(+) m6A CDS//exon//intron       24284625//22575960//22608085 chr20:39803119-39803120(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr20:39803135-39803136(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr20:39803207-39803208(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr20:39803289-39803290(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr20:39803295-39803296(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr20:39803363-39803364(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:39803442-39803443(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:39803496-39803497(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:39803561-39803562(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr20:39803591-39803592(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr20:39803704-39803705(+) m6A 3'UTR//intron       24209618//25456834//24981863//22608085 chr20:39803738-39803739(+) m6A 3'UTR//intron       24209618//25456834//24981863 chr20:39803855-39803856(+) m6A 3'UTR//intron       - chr20:39803902-39803903(+) m6A 3'UTR//intron       24981863 chr20:39804193-39804194(+) m6A 3'UTR//intron       24284625 chr20:39804263-39804264(+) m6A 3'UTR//intron       24284625 chr20:39814223-39814224(+) m6A exon//intron       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PLCG1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART4-3p
Interactor2: PLCG1

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg