Detail Information

Basic Information:


  VIRBase ID:  

VHID00408720

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART4-3p:           NFE2L2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol ebv-miR-BART4-3p NFE2L2
miRBase
Accession/Entrez ID		 MIMAT0009204 4780
Organism Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) Homo sapiens
Category miRNA mRNA
Alias - HEBP1//IMDDHH//Nrf-2//NRF2

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR NFE2L2
chr2:178112277(-) A-I      intronic
chr2:178102403(-) A-I      intronic
chr2:178100411(-) A-I      intronic
chr2:178100460(-) A-I      intronic
chr2:178120432(-) A-I      intronic
chr2:178120426(-) A-I      intronic
chr2:178120403(-) A-I      intronic
chr2:178113691(-) A-I      intronic
chr2:178112267(-) A-I      intronic
chr2:178100522(-) A-I      intronic
chr2:178112225(-) A-I      intronic
chr2:178100469(-) A-I      intronic
chr2:178100495(-) A-I      intronic
chr2:178101725(-) A-I      intronic
chr2:178101721(-) A-I      intronic
chr2:178101714(-) A-I      intronic
chr2:178113266(-) A-I      intronic
chr2:178112379(-) A-I      intronic
chr2:178106500(-) A-I      intronic
chr2:178102395(-) A-I      intronic
chr2:178100455(-) A-I      intronic
chr2:178100113(-) A-I      intronic
chr2:178102343(-) A-I      intronic
chr2:178102362(-) A-I      intronic
chr2:178104233(-) A-I      intronic
chr2:178104239(-) A-I      intronic
chr2:178104391(-) A-I      intronic
chr2:178109478(-) A-I      intronic
chr2:178113271(-) A-I      intronic
chr2:178113298(-) A-I      intronic
chr2:178113370(-) A-I      intronic
chr2:178113701(-) A-I      intronic
chr2:178113728(-) A-I      intronic
chr2:178113824(-) A-I      intronic
chr2:178120544(-) A-I      intronic
chr2:178124396(-) A-I      intronic
chr2:178124404(-) A-I      intronic
chr2:178124512(-) A-I      intronic
chr2:178102489(-) A-I      intronic
chr2:178102371(-) A-I      intronic
chr2:178102384(-) A-I      intronic
chr2:178104225(-) A-I      intronic
chr2:178100374(-) A-I      intronic
chr2:178100336(-) A-I      intronic
chr2:178099769(-) A-I      intronic
chr2:178099762(-) A-I      intronic
chr2:178101811(-) A-I      intronic
chr2:178099712(-) A-I      intronic
chr2:178102385(-) A-I      intronic
chr2:178111539(-) A-I      intronic
chr2:178099614(-) A-I      intronic
chr2:178101830(-) A-I      intronic
chr2:178101834(-) A-I      intronic
chr2:178101855(-) A-I      intronic
chr2:178102312(-) A-I      intronic
chr2:178102314(-) A-I      intronic
chr2:178102323(-) A-I      intronic
chr2:178100517(-) A-I      intronic
chr2:178099678(-) A-I      intronic
chr2:178104323(-) A-I      intronic
chr2:178112272(-) A-I      intronic
chr2:178100472(-) A-I      intronic
chr2:178109545(-) A-I      intronic
chr2:178113864(-) A-I      intronic
chr2:178109619(-) A-I      intronic
chr2:178109655(-) A-I      intronic
chr2:178101843(-) A-I      intronic
chr2:178101708(-) A-I      intronic
chr2:178101829(-) A-I      intronic
chr2:178123793(-) A-I      intronic
chr2:178101731(-) A-I      intronic
chr2:178113315(-) A-I      intronic
chr2:178113878(-) A-I      intronic
chr2:178113393(-) A-I      intronic
chr2:178113341(-) A-I      intronic
chr2:178111590(-) A-I      intronic
chr2:178120466(-) A-I      intronic
chr2:178113855(-) A-I      intronic
chr2:178109584(-) A-I      intronic
chr2:178125741(-) A-I      intronic
chr2:178124496(-) A-I      intronic
chr2:178100384(-) A-I      intronic
chr2:178101664(-) A-I      intronic
chr2:178100445(-) A-I      intronic
chr2:178100443(-) A-I      intronic
chr2:178100065(-) A-I      intronic
chr2:178113270(-) A-I      intronic
chr2:178099664(-) A-I      intronic
chr2:178101618(-) A-I      intronic
chr2:178113779(-) A-I      intronic
chr2:178111569(-) A-I      intronic
chr2:178113715(-) A-I      intronic
chr2:178101861(-) A-I      intronic
chr2:178113275(-) A-I      intronic
chr2:178120404(-) A-I      intronic
chr2:178120561(-) A-I      intronic
chr2:178104398(-) A-I      intronic
chr2:178123908(-) A-I      intronic
chr2:178113369(-) A-I      intronic
chr2:178101757(-) A-I      intronic
chr2:178099622(-) A-I      intronic
chr2:178100337(-) A-I      intronic
chr2:178124471(-) A-I      intronic
chr2:178111582(-) A-I      intronic
chr2:178124016(-) A-I      intronic
chr2:178102344(-) A-I      intronic
chr2:178100468(-) A-I      intronic
chr2:178112145(-) A-I      intronic
chr2:178113409(-) A-I      intronic
chr2:178113777(-) A-I      intronic
chr2:178099652(-) A-I      intronic
chr2:178102526(-) A-I      intronic
chr2:178123781(-) A-I      intronic
chr2:178100446(-) A-I      intronic
chr2:178100301(-) A-I      intronic
chr2:178100354(-) A-I      intronic
chr2:178101791(-) A-I      intronic
chr2:178113900(-) A-I      intronic
chr2:178120539(-) A-I      intronic
chr2:178100473(-) A-I      intronic
chr2:178100433(-) A-I      intronic
chr2:178100423(-) A-I      intronic
chr2:178113276(-) A-I      intronic
chr2:178101690(-) A-I      intronic
chr2:178101860(-) A-I      intronic
chr2:178100357(-) A-I      intronic
chr2:178102429(-) A-I      intronic
chr2:178099782(-) A-I      intronic
chr2:178124573(-) A-I      intronic
chr2:178113911(-) A-I      intronic
chr2:178102329(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED NFE2L2
chr2:178108331(-) A-I intron -    15342557
chr2:178108346(-) A-I intron -    15342557
chr2:178108351(-) A-I intron -    15342557
chr2:178108365(-) A-I intron -    15342557
chr2:178108377(-) A-I intron -    15342557
chr2:178108416(-) A-I intron -    15342557   //22327324
chr2:178108459(-) A-I intron -    15342557
chr2:178108794(-) A-I intron -    15342557
chr2:178108839(-) A-I intron -    15342557
chr2:178108861(-) A-I intron -    15342557
chr2:178108864(-) A-I intron -    15342557
chr2:178108929(-) A-I intron -    15342557
chr2:178108946(-) A-I intron -    15342557
chr2:178108947(-) A-I intron -    15342557
chr2:178108967(-) A-I intron -    15342557
chr2:178108991(-) A-I intron -    15342557
chr2:178111435(-) A-I intron -    15342557
chr2:178111449(-) A-I intron -    15342557
chr2:178111452(-) A-I intron -    15342557
chr2:178111465(-) A-I intron -    15342557
chr2:178111482(-) A-I intron -    15342557
chr2:178101843(-) A-I intron -    22327324
chr2:178100387(-) A-I intron -    21960545
chr2:178100443(-) A-I intron -    21960545
chr2:178100503(-) A-I intron -    21960545
chr2:178113824(-) A-I intron -    21960545
chr2:178113826(-) A-I intron -    21960545
chr2:178099652(-) A-G intron -    22484847
chr2:178099664(-) A-G intron -    22484847
chr2:178099704(-) A-G intron -    22484847
chr2:178100065(-) A-G intron -    22484847
chr2:178100139(-) G-A intron -    22484847
chr2:178100348(-) T-C intron -    22484847
chr2:178100384(-) A-G intron -    22484847
chr2:178100387(-) A-G intron -    22484847
chr2:178100406(-) A-G intron -    22484847
chr2:178100443(-) A-G intron -    22484847
chr2:178100445(-) A-G intron -    22484847
chr2:178100458(-) T-C intron -    22484847
chr2:178100472(-) A-G intron -    22484847
chr2:178100473(-) A-G intron -    22484847
chr2:178100503(-) A-G intron -    22484847
chr2:178100528(-) A-G intron -    22484847
chr2:178101650(-) A-G intron -    22484847
chr2:178101664(-) A-G intron -    22484847
chr2:178101708(-) A-G intron -    22484847
chr2:178101731(-) A-G intron -    22484847
chr2:178101757(-) A-G intron -    22484847
chr2:178101843(-) A-G intron -    22484847
chr2:178104398(-) A-G intron -    22484847
chr2:178108331(-) A-G intron -    22484847
chr2:178108346(-) A-G intron -    22484847
chr2:178108351(-) A-G intron -    22484847
chr2:178108413(-) A-G intron -    22484847
chr2:178108416(-) A-G intron -    22484847
chr2:178108459(-) A-G intron -    22484847
chr2:178108505(-) A-G intron -    22484847
chr2:178108784(-) A-G intron -    22484847
chr2:178108799(-) A-G intron -    22484847
chr2:178108839(-) A-G intron -    22484847
chr2:178108861(-) A-G intron -    22484847
chr2:178108864(-) A-G intron -    22484847
chr2:178108946(-) A-G intron -    22484847
chr2:178108947(-) A-G intron -    22484847
chr2:178108967(-) A-G intron -    22484847
chr2:178109545(-) A-G intron -    22484847
chr2:178109583(-) A-G intron -    22484847
chr2:178109584(-) A-G intron -    22484847
chr2:178109619(-) A-G intron -    22484847
chr2:178109655(-) A-G intron -    22484847
chr2:178110466(-) A-G intron -    22484847
chr2:178110470(-) A-G intron -    22484847
chr2:178110494(-) A-G intron -    22484847
chr2:178110505(-) A-G intron -    22484847
chr2:178110508(-) A-G intron -    22484847
chr2:178110514(-) A-G intron -    22484847
chr2:178110534(-) A-G intron -    22484847
chr2:178110541(-) A-G intron -    22484847
chr2:178110542(-) A-G intron -    22484847
chr2:178110580(-) A-G intron -    22484847
chr2:178110627(-) A-G intron -    22484847
chr2:178113248(-) A-G intron -    22484847
chr2:178113270(-) A-G intron -    22484847
chr2:178113275(-) A-G intron -    22484847
chr2:178113276(-) A-G intron -    22484847
chr2:178113294(-) A-G intron -    22484847
chr2:178113700(-) A-G intron -    22484847
chr2:178113715(-) A-G intron -    22484847
chr2:178113727(-) A-G intron -    22484847
chr2:178113777(-) A-G intron -    22484847
chr2:178113779(-) A-G intron -    22484847
chr2:178113836(-) A-G intron -    22484847
chr2:178113855(-) A-G intron -    22484847
chr2:178113942(-) G-T intron -    22484847
chr2:178113944(-) G-T intron -    22484847
chr2:178120404(-) A-G intron -    22484847
chr2:178123953(-) A-G intron -    22484847
chr2:178124471(-) A-G intron -    22484847
chr2:178124496(-) A-G intron -    22484847
chr2:178124573(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase NFE2L2
chr2:178092411-178092412(-) m6A 3'UTR       24284625//24981863//27773535
chr2:178092430-178092431(-) m6A 3'UTR       24284625//24981863//27773535
chr2:178092449-178092450(-) m6A 3'UTR       24284625//24981863//27773535
chr2:178092456-178092457(-) m6A 3'UTR       24284625//24981863//27773535
chr2:178092471-178092472(-) m6A 3'UTR       24284625
chr2:178092516-178092517(-) m6A 3'UTR       24284625
chr2:178092675-178092676(-) m6A CDS       27773535
chr2:178094080-178094081(-) m6A intron       24284625
chr2:178094090-178094091(-) m6A intron       24284625
chr2:178094153-178094154(-) m6A intron       24284625
chr2:178095131-178095132(-) m6A 3'UTR//intron       27773535
chr2:178095168-178095169(-) m6A 3'UTR//intron       27773535
chr2:178095255-178095256(-) m6A 3'UTR//intron       26404942//27773535
chr2:178095299-178095300(-) m6A 3'UTR//intron       26404942
chr2:178095312-178095313(-) m6A 3'UTR//intron       26404942
chr2:178095370-178095371(-) m6A 3'UTR//intron       26404942//27773535
chr2:178095393-178095394(-) m6A 3'UTR//intron       26404942//27773535
chr2:178095516-178095517(-) m6A CDS//intron       26404942//27773535//22575960
chr2:178095574-178095575(-) m6A CDS//intron       24284625//26404942//27773535//22575960//22608085
chr2:178095608-178095609(-) m6A CDS//intron       24284625//24981863//26404942//27773535//22575960//22608085
chr2:178095665-178095666(-) m6A CDS//intron       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr2:178095758-178095759(-) m6A CDS//intron       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr2:178095776-178095777(-) m6A CDS//intron       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr2:178095956-178095957(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//22575960//22608085
chr2:178095999-178096000(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//22575960//22608085
chr2:178096015-178096016(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//22575960//22608085
chr2:178096059-178096060(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr2:178096147-178096148(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr2:178096163-178096164(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr2:178096227-178096228(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr2:178096256-178096257(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr2:178096284-178096285(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr2:178096338-178096339(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr2:178096397-178096398(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr2:178096448-178096449(-) Y CDS//intron       25219674
chr2:178096524-178096525(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr2:178096545-178096546(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr2:178096655-178096656(-) Y CDS//intron       26075521
chr2:178096673-178096674(-) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//22608085
chr2:178096702-178096703(-) m6A CDS//intron       24284625//24209618//26404942//27773535//22608085
chr2:178098806-178098807(-) m6A CDS//exon//intron       24981863//26404942
chr2:178098864-178098865(-) m6A CDS//exon//intron       24981863//26404942//27773535
chr2:178098870-178098871(-) m6A CDS//exon//intron       24981863//26404942//27773535
chr2:178098885-178098886(-) m6A CDS//exon//intron       24981863//26404942//27773535
chr2:178098894-178098895(-) m6A CDS//exon//intron       24981863//26404942//27773535
chr2:178128259-178128260(-) m6A 5'UTR//exon//intron       -
chr2:178128283-178128284(-) m6A 5'UTR//intron       -
chr2:178128440-178128441(-) m6A 5'UTR//intron       25456834//27371828
chr2:178129274-178129275(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960
chr2:178129296-178129297(-) m6A CDS//exon//intron       24284625//24209618//24981863//27371828//27773536//22575960
chr2:178129349-178129350(-) m6A 5'UTR//exon//intron       24284625//24209618//24981863//27371828//27773536//22575960
chr2:178129517-178129518(-) m6A 5'UTR//intron       25456834//24981863
chr2:178129695-178129696(-) m6A 5'UTR//intron       24981863//22575960
chr2:178129749-178129750(-) m6A 5'UTR//intron       24981863
chr2:178129768-178129769(-) m6A 5'UTR//intron       24981863
chr2:178129787-178129788(-) m6A 5'UTR//intron       24284625//24981863
chr2:178148353-178148354(-) m6A 5'UTR//intron       24284625//27773535
chr2:178148382-178148383(-) m6A 5'UTR//intron       24284625//27773535
chr2:178148389-178148390(-) m6A 5'UTR//intron       27773535
chr2:178148394-178148395(-) m6A 5'UTR//intron       27773535
chr2:178148409-178148410(-) m6A 5'UTR//intron       27773535
chr2:178152243-178152244(-) m6A intron       -
chr2:178152303-178152304(-) m6A intron       -
chr2:178152309-178152310(-) m6A intron       -
chr2:178175606-178175607(-) m6A intron       24284625//22575960
chr2:178175620-178175621(-) m6A intron       24284625//22575960
chr2:178175693-178175694(-) m6A CDS//intron       -
chr2:178175702-178175703(-) m6A CDS//intron       -
chr2:178176015-178176016(-) m6A 5'UTR//intron       24284625
chr2:178186661-178186662(-) m6A intron       27773535
chr2:178187882-178187883(-) m6A intron       25456834//27773535//22608085
chr2:178187925-178187926(-) m6A intron       25456834//27773535//22608085
chr2:178187951-178187952(-) m6A intron       24284625//25456834//27773535//22608085
chr2:178188035-178188036(-) m6A 5'UTR       25456834//27773535//22608085
chr2:178188052-178188053(-) m6A 5'UTR       27773535
chr2:178206846-178206847(-) m6A intron       -
chr2:178206879-178206880(-) m6A intron       -
chr2:178206910-178206911(-) m6A intron       -
chr2:178206921-178206922(-) m6A intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate NFE2L2
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)|K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: ebv-miR-BART4-3p
Interactor2: NFE2L2

Evidence Support:


Weak-Evidence PAR-CLIP
Prediction-Evidence miRanda//PARalyzer//PITA//Targetscan
Support Database ViRBase//VIRmiRNA//VmiReg

References:


PMID 22291592 Target region 3'UTR
Source ViRBase//VIRmiRNA//VmiReg Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7,827 miRNA-interaction sites in 3,492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.We identified an additional 2,972 CDS miRNA-interaction sites present in at least two libraries, 89.7% of which could be assigned to a miRNA (Table S7).

Starting a new search, please wait ...