Basic Information:

  VIRBase ID:  

VHID00405348

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART19-5p:  MIMAT0004836          CASP10:  NM_001230     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART19-5p	CASP10
miRBase Accession/Entrez ID	MIMAT0004836	843
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ALPS2//FLICE-2//FLICE2//MCH4

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CASP10	chr2:202077289(+) A-I      intronic chr2:202077308(+) A-I      intronic chr2:202077298(+) A-I      intronic chr2:202077283(+) A-I      intronic chr2:202077280(+) A-I      intronic chr2:202077274(+) A-I      intronic chr2:202083746(+) A-I      3'UTR chr2:202083768(+) A-I      3'UTR chr2:202083778(+) A-I      3'UTR chr2:202083897(+) A-I      3'UTR chr2:202083902(+) A-I      3'UTR chr2:202083973(+) A-I      3'UTR chr2:202063926(+) A-I      intronic chr2:202092825(+) A-I      intronic chr2:202092844(+) A-I      intronic chr2:202080994(+) A-I      intronic chr2:202092797(+) A-I      intronic chr2:202053650(+) A-I      intronic chr2:202077322(+) A-I      intronic chr2:202053797(+) A-I      intronic chr2:202092830(+) A-I      intronic chr2:202092839(+) A-I      intronic chr2:202082763(+) A-I      3'UTR chr2:202092855(+) A-I      intronic chr2:202077259(+) A-I      intronic chr2:202077264(+) A-I      intronic chr2:202077265(+) A-I      intronic chr2:202083125(+) A-I      3'UTR chr2:202077268(+) A-I      intronic chr2:202092858(+) A-I      intronic chr2:202064495(+) A-I      intronic chr2:202083287(+) A-I      3'UTR chr2:202083743(+) A-I      3'UTR chr2:202054144(+) A-I      intronic chr2:202053015(+) A-I      intronic chr2:202053711(+) A-I      intronic chr2:202053829(+) A-I      intronic chr2:202053838(+) A-I      intronic chr2:202053855(+) A-I      intronic chr2:202053856(+) A-I      intronic chr2:202053857(+) A-I      intronic chr2:202053887(+) A-I      intronic chr2:202054157(+) A-I      intronic chr2:202054166(+) A-I      intronic chr2:202054488(+) A-I      intronic chr2:202054512(+) A-I      intronic chr2:202054559(+) A-I      intronic chr2:202057010(+) A-I      intronic chr2:202057006(+) A-I      intronic chr2:202056863(+) A-I      intronic chr2:202056854(+) A-I      intronic chr2:202054575(+) A-I      intronic chr2:202092899(+) A-I      intronic chr2:202092834(+) A-I      intronic chr2:202092826(+) A-I      intronic chr2:202092513(+) A-I      intronic chr2:202092489(+) A-I      intronic chr2:202092397(+) A-I      intronic chr2:202092379(+) A-I      intronic chr2:202087079(+) A-I      intronic chr2:202087069(+) A-I      intronic chr2:202080604(+) A-I      intronic chr2:202076801(+) A-I      intronic chr2:202064119(+) A-I      intronic chr2:202082239(+) A-I      intronic chr2:202082237(+) A-I      intronic chr2:202082207(+) A-I      intronic chr2:202082171(+) A-I      intronic chr2:202080949(+) A-I      intronic chr2:202080605(+) A-I      intronic chr2:202073621(+) A-I      intronic chr2:202073559(+) A-I      intronic chr2:202073501(+) A-I      intronic chr2:202072134(+) A-I      intronic chr2:202071423(+) A-I      intronic chr2:202065874(+) A-I      intronic chr2:202064439(+) A-I      intronic chr2:202064432(+) A-I      intronic chr2:202064423(+) A-I      intronic chr2:202064391(+) A-I      intronic chr2:202064378(+) A-I      intronic chr2:202062250(+) A-I      intronic chr2:202062128(+) A-I      intronic chr2:202054561(+) A-I      intronic chr2:202061938(+) A-I      intronic chr2:202062247(+) A-I      intronic chr2:202083277(+) A-I      3'UTR chr2:202083913(+) A-I      3'UTR chr2:202083264(+) A-I      3'UTR chr2:202083138(+) A-I      3'UTR chr2:202083764(+) A-I      3'UTR chr2:202083759(+) A-I      3'UTR chr2:202083904(+) A-I      3'UTR chr2:202083958(+) A-I      3'UTR chr2:202082711(+) A-I      3'UTR chr2:202082867(+) A-I      3'UTR chr2:202083729(+) A-I      3'UTR chr2:202083817(+) A-I      3'UTR chr2:202083272(+) A-I      3'UTR chr2:202083792(+) A-I      3'UTR chr2:202083725(+) A-I      3'UTR chr2:202082907(+) A-I      3'UTR chr2:202083143(+) A-I      3'UTR chr2:202082866(+) A-I      3'UTR chr2:202083878(+) A-I      3'UTR chr2:202083942(+) A-I      3'UTR chr2:202083943(+) A-I      3'UTR chr2:202061883(+) A-I      intronic chr2:202091219(+) A-I      intronic chr2:202056956(+) A-I      intronic chr2:202080553(+) A-I      intronic chr2:202092898(+) A-I      intronic chr2:202087020(+) A-I      intronic chr2:202054652(+) A-I      intronic chr2:202081062(+) A-I      intronic chr2:202092979(+) A-I      intronic chr2:202086988(+) A-I      intronic chr2:202057059(+) A-I      intronic chr2:202062118(+) A-I      intronic chr2:202064112(+) A-I      intronic chr2:202064375(+) A-I      intronic chr2:202081011(+) A-I      intronic chr2:202082701(+) A-I      3'UTR chr2:202082723(+) A-I      3'UTR chr2:202082754(+) A-I      3'UTR chr2:202083093(+) A-I      3'UTR chr2:202082905(+) A-I      3'UTR chr2:202083895(+) A-I      3'UTR chr2:202082730(+) A-I      3'UTR chr2:202083286(+) A-I      3'UTR chr2:202083873(+) A-I      3'UTR chr2:202083872(+) A-I      3'UTR chr2:202083905(+) A-I      3'UTR chr2:202083975(+) A-I      3'UTR chr2:202083235(+) A-I      3'UTR chr2:202083126(+) A-I      3'UTR chr2:202083972(+) A-I      3'UTR chr2:202083197(+) A-I      3'UTR chr2:202083773(+) A-I      3'UTR chr2:202082704(+) A-I      3'UTR chr2:202082737(+) A-I      3'UTR chr2:202082762(+) A-I      3'UTR chr2:202083260(+) A-I      3'UTR chr2:202082776(+) A-I      3'UTR chr2:202083882(+) A-I      3'UTR chr2:202083914(+) A-I      3'UTR chr2:202083755(+) A-I      3'UTR chr2:202083925(+) A-I      3'UTR chr2:202082865(+) A-I      3'UTR chr2:202082662(+) A-I      3'UTR chr2:202064498(+) A-I      intronic chr2:202087162(+) A-I      intronic chr2:202071420(+) A-I      intronic chr2:202054560(+) A-I      intronic chr2:202092938(+) A-I      intronic chr2:202092795(+) A-I      intronic chr2:202061974(+) A-I      intronic chr2:202092820(+) A-I      intronic chr2:202054642(+) A-I      intronic chr2:202054601(+) A-I      intronic chr2:202054649(+) A-I      intronic chr2:202080971(+) A-I      intronic chr2:202071413(+) A-I      intronic chr2:202061889(+) A-I      intronic chr2:202072227(+) A-I      intronic chr2:202064415(+) A-I      intronic chr2:202054072(+) A-I      intronic chr2:202061920(+) A-I      intronic chr2:202054091(+) A-I      intronic chr2:202066014(+) A-I      intronic chr2:202072143(+) A-I      intronic chr2:202061890(+) A-I      intronic chr2:202062283(+) A-I      intronic chr2:202080995(+) A-I      intronic chr2:202053674(+) A-I      intronic chr2:202064559(+) A-I      intronic chr2:202092785(+) A-I      intronic chr2:202053624(+) A-I      intronic chr2:202064549(+) A-I      intronic chr2:202080977(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CASP10	chr2:202082668(+) A-I exon 3'UTR    15342557   //22327324 chr2:202083057(+) A-I exon 3'UTR    15342557 chr2:202083152(+) A-I exon 3'UTR    15342557 chr2:202083197(+) A-I exon 3'UTR    15342557 chr2:202083755(+) A-I exon 3'UTR    15342557 chr2:202083773(+) A-I exon 3'UTR    15342557 chr2:202083872(+) A-I exon 3'UTR    15342557   //22327324 chr2:202083905(+) A-I exon 3'UTR    15342557 chr2:202082730(+) A-I intron -    22327324 chr2:202083918(+) A-I intron -    22327324 chr2:202083057(+) A-G intron -    21725310   //22484847 chr2:202086083(+) T-C intron -    21725310 chr2:202054601(+) A-G intron -    22484847 chr2:202055641(+) A-G intron -    22484847 chr2:202061920(+) A-G intron -    22484847 chr2:202061974(+) A-G intron -    22484847 chr2:202062118(+) A-G intron -    22484847 chr2:202064549(+) A-G intron -    22484847 chr2:202071413(+) A-G intron -    22484847 chr2:202072143(+) A-G intron -    22484847 chr2:202072279(+) A-G intron -    22484847 chr2:202082668(+) A-G intron -    22484847 chr2:202082730(+) A-G intron -    22484847 chr2:202082762(+) A-G intron -    22484847 chr2:202083245(+) A-G intron -    22484847 chr2:202083872(+) A-G intron -    22484847 chr2:202083873(+) A-G intron -    22484847 chr2:202083899(+) A-G intron -    22484847 chr2:202083918(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CASP10	chr2:202047831-202047832(+) m6A 5'UTR       24981863 chr2:202047876-202047877(+) m6A 5'UTR//exon       24981863 chr2:202047927-202047928(+) m6A 5'UTR//exon       24981863 chr2:202047963-202047964(+) m6A 5'UTR//exon       24981863 chr2:202047991-202047992(+) m6A 5'UTR//exon       24981863 chr2:202073915-202073916(+) m6A 3'UTR//CDS//exon       - chr2:202074033-202074034(+) m6A 3'UTR//CDS//exon       25456834//24981863 chr2:202074045-202074046(+) m6A 3'UTR//CDS//exon       25456834//24981863 chr2:202074051-202074052(+) m6A 3'UTR//CDS//exon       25456834 chr2:202074122-202074123(+) m6A 3'UTR//CDS//exon       25456834//24981863 chr2:202074152-202074153(+) m6A 3'UTR//CDS//exon       25456834 chr2:202082380-202082381(+) m6A 3'UTR//CDS//exon//intron       24981863 chr2:202082388-202082389(+) m6A 3'UTR//CDS//exon//intron       24981863 chr2:202082424-202082425(+) m6A 3'UTR//CDS//exon//intron       24981863 chr2:202083711-202083712(+) m6A 3'UTR//intron       25456834//24981863 chr2:202083793-202083794(+) m6A 3'UTR//intron       25456834//24981863 chr2:202083816-202083817(+) m6A 3'UTR//intron       25456834//24981863 chr2:202083834-202083835(+) m6A 3'UTR//intron       25456834//24981863 chr2:202083982-202083983(+) m6A 3'UTR//intron       22608085 chr2:202084019-202084020(+) m6A 3'UTR//intron       22608085 chr2:202084042-202084043(+) m6A 3'UTR//intron       24981863//22608085 chr2:202084101-202084102(+) m6A 3'UTR//intron       25456834//24981863//22608085 chr2:202084146-202084147(+) m6A 3'UTR//intron       25456834//24981863//22608085 chr2:202084210-202084211(+) m6A 3'UTR//intron       25456834//24981863//22608085 chr2:202084220-202084221(+) m6A 3'UTR//intron       25456834//24981863//22608085 chr2:202084295-202084296(+) m6A 3'UTR//intron       24209618//25456834//24981863//22608085 chr2:202084460-202084461(+) m6A 3'UTR//intron       24209618//24981863//22608085 chr2:202084484-202084485(+) m6A 3'UTR//intron       24981863//22608085 chr2:202084587-202084588(+) m6A 3'UTR//intron       24981863//22608085 chr2:202084636-202084637(+) m6A 3'UTR//intron       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ebv-miR-BART19-5p	Exosome B cell line (Raji)     21505438
	CASP10	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART19-5p
Interactor2: CASP10

Evidence Support:

Prediction-Evidence	miRanda//PITA//Targetscan
Support Database	VmiReg