Basic Information:

  VIRBase ID:  

VHID00398928

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART10-5p:  MIMAT0004817          APAF1:  NM_181861     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART10-5p	APAF1
miRBase Accession/Entrez ID	MIMAT0004817	317
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	APAF-1//CED4

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	APAF1	chr12:99047358(+) A-I      intronic chr12:99058893(+) A-I      intronic chr12:99112527(+) A-I      intronic chr12:99058856(+) A-I      intronic chr12:99112503(+) A-I      intronic chr12:99047363(+) A-I      intronic chr12:99047344(+) A-I      intronic chr12:99047337(+) A-I      intronic chr12:99047320(+) A-I      intronic chr12:99047384(+) A-I      intronic chr12:99047306(+) A-I      intronic chr12:99047380(+) A-I      intronic chr12:99047284(+) A-I      intronic chr12:99045537(+) A-I      intronic chr12:99045493(+) A-I      intronic chr12:99045966(+) A-I      intronic chr12:99127336(+) A-I      3'UTR chr12:99112512(+) A-I      intronic chr12:99044074(+) A-I      intronic chr12:99058920(+) A-I      intronic chr12:99044075(+) A-I      intronic chr12:99058912(+) A-I      intronic chr12:99058911(+) A-I      intronic chr12:99058894(+) A-I      intronic chr12:99045538(+) A-I      intronic chr12:99047369(+) A-I      intronic chr12:99066775(+) A-I      intronic chr12:99067003(+) A-I      intronic chr12:99067044(+) A-I      intronic chr12:99067097(+) A-I      intronic chr12:99067142(+) A-I      intronic chr12:99067780(+) A-I      intronic chr12:99081611(+) A-I      intronic chr12:99081646(+) A-I      intronic chr12:99081755(+) A-I      intronic chr12:99083355(+) A-I      intronic chr12:99083498(+) A-I      intronic chr12:99083501(+) A-I      intronic chr12:99083519(+) A-I      intronic chr12:99096341(+) A-I      intronic chr12:99096383(+) A-I      intronic chr12:99096598(+) A-I      intronic chr12:99112054(+) A-I      intronic chr12:99112213(+) A-I      intronic chr12:99113228(+) A-I      intronic chr12:99113269(+) A-I      intronic chr12:99114602(+) A-I      intronic chr12:99114624(+) A-I      intronic chr12:99114630(+) A-I      intronic chr12:99114708(+) A-I      intronic chr12:99114753(+) A-I      intronic chr12:99066788(+) A-I      intronic chr12:99044185(+) A-I      intronic chr12:99044221(+) A-I      intronic chr12:99045488(+) A-I      intronic chr12:99045632(+) A-I      intronic chr12:99045750(+) A-I      intronic chr12:99045993(+) A-I      intronic chr12:99046544(+) A-I      intronic chr12:99046664(+) A-I      intronic chr12:99046677(+) A-I      intronic chr12:99047239(+) A-I      intronic chr12:99047276(+) A-I      intronic chr12:99047285(+) A-I      intronic chr12:99047417(+) A-I      intronic chr12:99048262(+) A-I      intronic chr12:99048303(+) A-I      intronic chr12:99048315(+) A-I      intronic chr12:99048407(+) A-I      intronic chr12:99053328(+) A-I      intronic chr12:99053359(+) A-I      intronic chr12:99053846(+) A-I      intronic chr12:99053874(+) A-I      intronic chr12:99053943(+) A-I      intronic chr12:99066023(+) A-I      intronic chr12:99066650(+) A-I      intronic chr12:99066763(+) A-I      intronic chr12:99066770(+) A-I      intronic chr12:99045517(+) A-I      intronic chr12:99045616(+) A-I      intronic chr12:99082733(+) A-I      intronic chr12:99112589(+) A-I      intronic chr12:99067082(+) A-I      intronic chr12:99045609(+) A-I      intronic chr12:99112510(+) A-I      intronic chr12:99053868(+) A-I      intronic chr12:99047179(+) A-I      intronic chr12:99053963(+) A-I      intronic chr12:99047385(+) A-I      intronic chr12:99041339(+) A-I      intronic chr12:99045705(+) A-I      intronic chr12:99047180(+) A-I      intronic chr12:99044059(+) A-I      intronic chr12:99047376(+) A-I      intronic chr12:99067083(+) A-I      intronic chr12:99044102(+) A-I      intronic chr12:99112542(+) A-I      intronic chr12:99045657(+) A-I      intronic chr12:99128848(+) A-I      3'UTR chr12:99127401(+) A-I      3'UTR chr12:99128844(+) A-I      3'UTR chr12:99128793(+) A-I      3'UTR chr12:99128847(+) A-I      3'UTR chr12:99127171(+) A-I      3'UTR chr12:99128787(+) A-I      3'UTR chr12:99127451(+) A-I      3'UTR chr12:99128748(+) A-I      3'UTR chr12:99127337(+) A-I      3'UTR chr12:99127285(+) A-I      3'UTR chr12:99128792(+) A-I      3'UTR chr12:99112203(+) A-I      intronic chr12:99045462(+) A-I      intronic chr12:99045693(+) A-I      intronic chr12:99044051(+) A-I      intronic chr12:99047355(+) A-I      intronic chr12:99103852(+) A-I      intronic chr12:99047259(+) A-I      intronic chr12:99045767(+) A-I      intronic chr12:99096589(+) A-I      intronic chr12:99046522(+) A-I      intronic chr12:99047392(+) A-I      intronic chr12:99053410(+) A-I      intronic chr12:99045798(+) A-I      intronic chr12:99047367(+) A-I      intronic chr12:99045710(+) A-I      intronic chr12:99045470(+) A-I      intronic chr12:99112517(+) A-I      intronic chr12:99112499(+) A-I      intronic chr12:99045512(+) A-I      intronic chr12:99112531(+) A-I      intronic chr12:99045613(+) A-I      intronic chr12:99045507(+) A-I      intronic chr12:99049423(+) A-I      intronic chr12:99045654(+) A-I      intronic chr12:99113257(+) A-I      intronic chr12:99047315(+) A-I      intronic chr12:99046005(+) A-I      intronic chr12:99112222(+) A-I      intronic chr12:99055335(+) A-I      intronic chr12:99082643(+) A-I      intronic chr12:99053320(+) A-I      intronic chr12:99049431(+) A-I      intronic chr12:99065977(+) A-I      intronic chr12:99067848(+) A-I      intronic chr12:99067146(+) A-I      intronic chr12:99047314(+) A-I      intronic chr12:99045614(+) A-I      intronic chr12:99096607(+) A-I      intronic chr12:99045854(+) A-I      intronic chr12:99098577(+) A-I      intronic chr12:99045732(+) A-I      intronic chr12:99046479(+) A-I      intronic chr12:99113267(+) A-I      intronic chr12:99066115(+) A-I      intronic chr12:99112150(+) A-I      intronic chr12:99045940(+) A-I      intronic chr12:99047202(+) A-I      intronic chr12:99053917(+) A-I      intronic chr12:99045992(+) A-I      intronic chr12:99112661(+) A-I      intronic chr12:99045855(+) A-I      intronic chr12:99049466(+) A-I      intronic chr12:99054780(+) A-I      intronic chr12:99066178(+) A-I      intronic chr12:99045692(+) A-I      intronic chr12:99067159(+) A-I      intronic chr12:99045920(+) A-I      intronic chr12:99046423(+) A-I      intronic chr12:99047220(+) A-I      intronic chr12:99054026(+) A-I      intronic chr12:99054953(+) A-I      intronic chr12:99047279(+) A-I      intronic chr12:99055393(+) A-I      intronic chr12:99047356(+) A-I      intronic chr12:99054025(+) A-I      intronic chr12:99045952(+) A-I      intronic chr12:99045758(+) A-I      intronic chr12:99047225(+) A-I      intronic chr12:99047270(+) A-I      intronic chr12:99046482(+) A-I      intronic chr12:99054781(+) A-I      intronic chr12:99082766(+) A-I      intronic chr12:99122236(+) A-I      intronic chr12:99047249(+) A-I      intronic chr12:99112152(+) A-I      intronic chr12:99067134(+) A-I      intronic chr12:99112036(+) A-I      intronic chr12:99040907(+) A-I      intronic chr12:99054798(+) A-I      intronic chr12:99044060(+) A-I      intronic chr12:99047153(+) A-I      intronic chr12:99067967(+) A-I      intronic chr12:99112632(+) A-I      intronic chr12:99127474(+) A-I      3'UTR chr12:99127091(+) A-I      3'UTR chr12:99127447(+) A-I      3'UTR chr12:99126935(+) A-I      3'UTR chr12:99128771(+) A-I      3'UTR chr12:99127345(+) A-I      3'UTR chr12:99127030(+) A-I      3'UTR chr12:99127234(+) A-I      3'UTR chr12:99127464(+) A-I      3'UTR chr12:99127446(+) A-I      3'UTR chr12:99127473(+) A-I      3'UTR chr12:99127013(+) A-I      3'UTR chr12:99127315(+) A-I      3'UTR chr12:99128811(+) A-I      3'UTR chr12:99127409(+) A-I      3'UTR chr12:99126937(+) A-I      3'UTR chr12:99127094(+) A-I      3'UTR chr12:99128776(+) A-I      3'UTR chr12:99128770(+) A-I      3'UTR chr12:99127350(+) A-I      3'UTR chr12:99128830(+) A-I      3'UTR chr12:99127328(+) A-I      3'UTR chr12:99127311(+) A-I      3'UTR chr12:99127412(+) A-I      3'UTR

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	APAF1	chr12:99126937(+) A-I exon 3'UTR    15258596 chr12:99127013(+) A-I exon 3'UTR    15258596 chr12:99127234(+) A-I exon 3'UTR    15258596 chr12:99127328(+) A-I exon 3'UTR    15258596 chr12:99127337(+) A-I exon 3'UTR    15258596 chr12:99127350(+) A-I exon 3'UTR    15258596 chr12:99127446(+) A-I exon 3'UTR    15258596   //22327324 chr12:99127447(+) A-I exon 3'UTR    15258596   //22327324 chr12:99127474(+) A-I intron -    22327324 chr12:99128776(+) A-I intron -    22327324 chr12:99128811(+) A-I intron -    22327324 chr12:99127446(+) A-G intron -    21725310   //22484847 chr12:99127474(+) A-G intron -    21725310   //22484847 chr12:99128792(+) A-G intron -    21725310 chr12:99045654(+) A-G intron -    22484847 chr12:99045657(+) A-G intron -    22484847 chr12:99045710(+) A-G intron -    22484847 chr12:99110904(+) C-A intron -    22484847 chr12:99127315(+) A-G intron -    22484847 chr12:99127328(+) A-G intron -    22484847 chr12:99127337(+) A-G intron -    22484847 chr12:99127350(+) A-G intron -    22484847 chr12:99127447(+) A-G intron -    22484847 chr12:99044086(+) T-C intron -    22484847 chr12:99047270(+) A-G intron -    22484847 chr12:99047314(+) A-G intron -    22484847 chr12:99053868(+) A-G intron -    22484847 chr12:99053963(+) A-G intron -    22484847 chr12:99054025(+) A-G intron -    22484847 chr12:99054026(+) A-G intron -    22484847 chr12:99054781(+) A-G intron -    22484847 chr12:99054798(+) A-G intron -    22484847 chr12:99054953(+) A-G intron -    22484847 chr12:99065977(+) A-G intron -    22484847 chr12:99066115(+) A-G intron -    22484847 chr12:99066984(+) C-G intron -    22484847 chr12:99067082(+) A-G intron -    22484847 chr12:99067083(+) A-G intron -    22484847 chr12:99067146(+) A-G intron -    22484847 chr12:99067848(+) A-G intron -    22484847 chr12:99067967(+) A-G intron -    22484847 chr12:99081629(+) G-A intron -    22484847 chr12:99096607(+) A-G intron -    22484847 chr12:99106614(+) G-T intron -    22484847 chr12:99112036(+) A-G intron -    22484847 chr12:99112203(+) A-G intron -    22484847 chr12:99112589(+) A-G intron -    22484847 chr12:99126925(+) G-T intron -    22484847 chr12:99127234(+) A-G intron -    22484847 chr12:99127345(+) A-G intron -    22484847 chr12:99127401(+) A-G intron -    22484847 chr12:99127412(+) A-G intron -    22484847 chr12:99127458(+) T-C intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	APAF1	chr12:99039080-99039081(+) m1A 5'UTR       26863196//26863410 chr12:99039130-99039131(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22608085 chr12:99039170-99039171(+) m6A 5'UTR       24284625//24209618//25456834//24981863//22608085 chr12:99039260-99039261(+) m6A 5'UTR       - chr12:99039337-99039338(+) m6A 5'UTR       - chr12:99039454-99039455(+) m6A 5'UTR       - chr12:99126332-99126333(+) m6A 3'UTR//CDS//exon       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	APAF1	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Nasopharyngeal carcinoma cells     20498841 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Nasopharyngeal carcinoma cells     20498841

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART10-5p
Interactor2: APAF1

Evidence Support:

Prediction-Evidence	miRanda//Targetscan
Support Database	VmiReg