Detail Information

Basic Information:


  VIRBase ID:  

VHID00381942

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART19-3p:           NIPA2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol ebv-miR-BART19-3p NIPA2
miRBase
Accession/Entrez ID
MIMAT0003718 81614
Organism Human gammaherpesvirus 4 (Epstein-Barr virus, EPV) Homo sapiens
Category miRNA mRNA
Alias - SLC57A2

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR NIPA2
chr15:23026292(-) A-I      intronic
chr15:23019577(-) A-I      intronic
chr15:23026417(-) A-I      intronic
chr15:23008016(-) A-I      intronic
chr15:23019055(-) A-I      intronic
chr15:23024407(-) A-I      intronic
chr15:23026405(-) A-I      intronic
chr15:23026267(-) A-I      intronic
chr15:23008065(-) A-I      intronic
chr15:23026270(-) A-I      intronic
chr15:23026268(-) A-I      intronic
chr15:23008026(-) A-I      intronic
chr15:23026398(-) A-I      intronic
chr15:23025504(-) A-I      intronic
chr15:23014041(-) A-I      intronic
chr15:23026413(-) A-I      intronic
chr15:23008081(-) A-I      intronic
chr15:23025430(-) A-I      intronic
chr15:23014145(-) A-I      intronic
chr15:23026375(-) A-I      intronic
chr15:23029608(-) A-I      intronic
chr15:23024291(-) A-I      intronic
chr15:23024302(-) A-I      intronic
chr15:23026510(-) A-I      intronic
chr15:23024376(-) A-I      intronic
chr15:23024381(-) A-I      intronic
chr15:23024420(-) A-I      intronic
chr15:23025404(-) A-I      intronic
chr15:23025464(-) A-I      intronic
chr15:23018484(-) A-I      intronic
chr15:23018469(-) A-I      intronic
chr15:23018453(-) A-I      intronic
chr15:23018400(-) A-I      intronic
chr15:23013502(-) A-I      intronic
chr15:23014938(-) A-I      intronic
chr15:23014717(-) A-I      intronic
chr15:23014123(-) A-I      intronic
chr15:23014015(-) A-I      intronic
chr15:23018475(-) A-I      intronic
chr15:23014005(-) A-I      intronic
chr15:23014001(-) A-I      intronic
chr15:23013646(-) A-I      intronic
chr15:23013636(-) A-I      intronic
chr15:23013634(-) A-I      intronic
chr15:23018802(-) A-I      intronic
chr15:23007837(-) A-I      intronic
chr15:23017843(-) A-I      intronic
chr15:23015797(-) A-I      intronic
chr15:23019133(-) A-I      intronic
chr15:23013515(-) A-I      intronic
chr15:23013514(-) A-I      intronic
chr15:23007744(-) A-I      intronic
chr15:23007703(-) A-I      intronic
chr15:23015751(-) A-I      intronic
chr15:23007689(-) A-I      intronic
chr15:23017712(-) A-I      intronic
chr15:23025486(-) A-I      intronic
chr15:23025940(-) A-I      intronic
chr15:23017762(-) A-I      intronic
chr15:23025973(-) A-I      intronic
chr15:23026012(-) A-I      intronic
chr15:23026287(-) A-I      intronic
chr15:23008080(-) A-I      intronic
chr15:23026358(-) A-I      intronic
chr15:23026363(-) A-I      intronic
chr15:23026367(-) A-I      intronic
chr15:23026526(-) A-I      intronic
chr15:23026533(-) A-I      intronic
chr15:23018579(-) A-I      intronic
chr15:23029656(-) A-I      intronic
chr15:23030503(-) A-I      intronic
chr15:23030507(-) A-I      intronic
chr15:23030508(-) A-I      intronic
chr15:23032886(-) A-I      intronic
chr15:23033035(-) A-I      intronic
chr15:23007680(-) A-I      intronic
chr15:23007662(-) A-I      intronic
chr15:23007661(-) A-I      intronic
chr15:23007637(-) A-I      intronic
chr15:23007622(-) A-I      intronic
chr15:23007595(-) A-I      intronic
chr15:23007580(-) A-I      intronic
chr15:23017841(-) A-I      intronic
chr15:23019430(-) A-I      intronic
chr15:23028593(-) A-I      intronic
chr15:23018732(-) A-I      intronic
chr15:23019565(-) A-I      intronic
chr15:23019060(-) A-I      intronic
chr15:23019057(-) A-I      intronic
chr15:23019079(-) A-I      intronic
chr15:23019111(-) A-I      intronic
chr15:23019431(-) A-I      intronic
chr15:23018532(-) A-I      intronic
chr15:23019553(-) A-I      intronic
chr15:23019615(-) A-I      intronic
chr15:23017772(-) A-I      intronic
chr15:23019655(-) A-I      intronic
chr15:23018681(-) A-I      intronic
chr15:23013577(-) A-I      intronic
chr15:23014073(-) A-I      intronic
chr15:23026323(-) A-I      intronic
chr15:23007729(-) A-I      intronic
chr15:23017847(-) A-I      intronic
chr15:23019671(-) A-I      intronic
chr15:23026411(-) A-I      intronic
chr15:23012868(-) A-I      intronic
chr15:23029276(-) A-I      intronic
chr15:23019101(-) A-I      intronic
chr15:23019051(-) A-I      intronic
chr15:23015799(-) A-I      intronic
chr15:23026484(-) A-I      intronic
chr15:23025439(-) A-I      intronic
chr15:23024402(-) A-I      intronic
chr15:23019528(-) A-I      intronic
chr15:23029097(-) A-I      intronic
chr15:23028635(-) A-I      intronic
chr15:23018482(-) A-I      intronic
chr15:23019472(-) A-I      intronic
chr15:23018339(-) A-I      intronic
chr15:23023428(-) A-I      intronic
chr15:23013591(-) A-I      intronic
chr15:23008175(-) A-I      intronic
chr15:23012932(-) A-I      intronic
chr15:23025424(-) A-I      intronic
chr15:23030176(-) A-I      intronic
chr15:23024394(-) A-I      intronic
chr15:23025395(-) A-I      intronic
chr15:23030289(-) A-I      intronic
chr15:23018485(-) A-I      intronic
chr15:23026031(-) A-I      5'UTR
chr15:23026065(-) A-I      5'UTR
chr15:23026030(-) A-I      5'UTR
chr15:23026628(-) A-I      intronic
chr15:23012968(-) A-I      intronic
chr15:23008145(-) A-I      intronic
chr15:23019471(-) A-I      intronic
chr15:23029288(-) A-I      intronic
chr15:23028504(-) A-I      intronic
chr15:23025982(-) A-I      intronic
chr15:23029224(-) A-I      intronic
chr15:23018800(-) A-I      intronic
chr15:23018753(-) A-I      intronic
chr15:23018402(-) A-I      intronic
chr15:23026402(-) A-I      intronic
chr15:23026509(-) A-I      intronic
chr15:23015346(-) A-I      intronic
chr15:23024499(-) A-I      intronic
chr15:23019140(-) A-I      intronic
chr15:23018410(-) A-I      intronic
chr15:23008077(-) A-I      intronic
chr15:23017858(-) A-I      intronic
chr15:23019595(-) A-I      intronic
chr15:23015310(-) A-I      intronic
chr15:23013600(-) A-I      intronic
chr15:23026432(-) A-I      intronic
chr15:23017719(-) A-I      intronic
chr15:23014080(-) A-I      intronic
chr15:23008113(-) A-I      intronic
chr15:23017910(-) A-I      intronic
chr15:23026414(-) A-I      intronic
chr15:23015352(-) A-I      intronic
chr15:23015342(-) A-I      intronic
chr15:23019188(-) A-I      intronic
chr15:23019512(-) A-I      intronic
chr15:23018767(-) A-I      intronic
chr15:23014722(-) A-I      intronic
chr15:23007934(-) A-I      intronic
chr15:23019075(-) A-I      intronic
chr15:23025421(-) A-I      intronic
chr15:23028634(-) A-I      intronic
chr15:23030333(-) A-I      intronic
chr15:23024353(-) A-I      intronic
chr15:23024219(-) A-I      intronic
chr15:23029805(-) A-I      intronic
chr15:23019212(-) A-I      intronic
chr15:23026465(-) A-I      intronic
chr15:23029136(-) A-I      intronic
chr15:23019509(-) A-I      intronic
chr15:23031442(-) A-I      intronic
chr15:23032992(-) A-I      intronic
chr15:23007594(-) A-I      intronic
chr15:23017771(-) A-I      intronic
chr15:23029226(-) A-I      intronic
chr15:23025552(-) A-I      intronic
chr15:23029337(-) A-I      intronic
chr15:23019594(-) A-I      intronic
chr15:23024452(-) A-I      intronic
chr15:23018928(-) A-I      intronic
chr15:23019219(-) A-I      intronic
chr15:23023298(-) A-I      intronic
chr15:23018841(-) A-I      intronic
chr15:23023323(-) A-I      intronic
chr15:23025500(-) A-I      intronic
chr15:23029324(-) A-I      intronic
chr15:23013594(-) A-I      intronic
chr15:23029236(-) A-I      intronic
chr15:23029110(-) A-I      intronic
chr15:23012908(-) A-I      intronic
chr15:23013695(-) A-I      intronic
chr15:23031511(-) A-I      intronic
chr15:23019074(-) A-I      intronic
chr15:23023320(-) A-I      intronic
chr15:23032982(-) A-I      intronic
chr15:23024404(-) A-I      intronic
chr15:23018401(-) A-I      intronic
chr15:23013649(-) A-I      intronic
chr15:23025477(-) A-I      intronic
chr15:23025382(-) A-I      intronic
chr15:23019555(-) A-I      intronic
chr15:23018741(-) A-I      intronic
chr15:23017723(-) A-I      intronic
chr15:23025200(-) A-I      intronic
chr15:23024363(-) A-I      intronic
chr15:23020759(-) A-I      intronic
chr15:23017672(-) A-I      intronic
chr15:23029353(-) A-I      intronic
chr15:23019106(-) A-I      intronic
chr15:23026337(-) A-I      intronic
chr15:23018840(-) A-I      intronic
chr15:23018483(-) A-I      intronic
chr15:23029170(-) A-I      intronic
chr15:23026415(-) A-I      intronic
chr15:23025478(-) A-I      intronic
chr15:23015243(-) A-I      intronic
chr15:23008137(-) A-I      intronic
chr15:23018860(-) A-I      intronic
chr15:23025326(-) A-I      intronic
chr15:23029714(-) A-I      intronic
chr15:23013696(-) A-I      intronic
chr15:23026416(-) A-I      intronic
chr15:23018433(-) A-I      intronic
chr15:23026332(-) A-I      intronic
chr15:23007845(-) A-I      intronic
chr15:23028460(-) A-I      intronic
chr15:23015489(-) A-I      intronic
chr15:23014146(-) A-I      intronic
chr15:23014832(-) A-I      intronic
chr15:23032874(-) A-I      intronic
chr15:23028594(-) A-I      intronic
chr15:23015703(-) A-I      intronic
chr15:23028648(-) A-I      intronic
chr15:23015742(-) A-I      intronic
chr15:23026488(-) A-I      intronic
chr15:23018488(-) A-I      intronic
chr15:23008170(-) A-I      intronic
chr15:23007739(-) A-I      intronic
chr15:23018669(-) A-I      intronic
chr15:23018969(-) A-I      intronic
chr15:23019166(-) A-I      intronic
chr15:23018758(-) A-I      intronic
chr15:23029161(-) A-I      intronic
chr15:23019620(-) A-I      intronic
chr15:23026516(-) A-I      intronic
chr15:23025928(-) A-I      intronic
chr15:23026311(-) A-I      intronic
chr15:23029827(-) A-I      intronic
chr15:23028691(-) A-I      intronic
chr15:23023254(-) A-I      intronic
chr15:23025503(-) A-I      intronic
chr15:23030551(-) A-I      intronic
chr15:23025438(-) A-I      intronic
chr15:23018691(-) A-I      intronic
chr15:23018442(-) A-I      intronic
chr15:23029398(-) A-I      intronic
chr15:23030350(-) A-I      intronic
chr15:23018443(-) A-I      intronic
chr15:23015798(-) A-I      intronic
chr15:23026100(-) A-I      5'UTR
chr15:23026090(-) A-I      5'UTR
chr15:23026064(-) A-I      5'UTR
chr15:23029841(-) A-I      5'UTR
chr15:23026025(-) A-I      5'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED NIPA2
chr15:23026465(-) A-I intron -    22327324
chr15:23005380(-) T-G exon 3'UTR    21725310
chr15:23007594(-) A-G intron -    22484847
chr15:23008081(-) A-G intron -    22484847
chr15:23013611(-) T-C intron -    22484847
chr15:23015751(-) A-G intron -    22484847
chr15:23017712(-) A-G intron -    22484847
chr15:23017719(-) A-G intron -    22484847
chr15:23017762(-) A-G intron -    22484847
chr15:23017771(-) A-G intron -    22484847
chr15:23017772(-) A-G intron -    22484847
chr15:23017841(-) A-G intron -    22484847
chr15:23017843(-) A-G intron -    22484847
chr15:23018741(-) A-G intron -    22484847
chr15:23019212(-) A-G intron -    22484847
chr15:23025552(-) A-G intron -    22484847
chr15:23026064(-) A-G exon 5'UTR    22484847
chr15:23026065(-) A-G exon 5'UTR    22484847
chr15:23026332(-) A-G intron -    22484847
chr15:23026337(-) A-G intron -    22484847
chr15:23026465(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase NIPA2
chr15:23005387-23005388(-) Y 3'UTR       26075521
chr15:23005678-23005679(-) m6A 3'UTR       27773535
chr15:23005694-23005695(-) m6A 3'UTR       27773535
chr15:23006274-23006275(-) m6A CDS       24981863
chr15:23006407-23006408(-) Y CDS       26075521
chr15:23006773-23006774(-) m6A CDS       24284625//24981863//22608085
chr15:23006777-23006778(-) m6A CDS       22575960
chr15:23006781-23006782(-) m6A CDS       24284625//24981863//22608085
chr15:23012314-23012315(-) m6A CDS       24284625
chr15:23034231-23034232(-) m6A 5'UTR//exon       25456834//24981863//27371828//27773536//22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate ebv-miR-BART19-3p
Exosome Primary dendritic cells|T cell line (J77)     21505438
NIPA2
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: ebv-miR-BART19-3p
Interactor2: NIPA2

Evidence Support:


Weak-Evidence PAR-CLIP
Prediction-Evidence miRanda//PARalyzer//Targetscan
Support Database ViRBase//VIRmiRNA//VmiReg

References:


PMID 22100165 Target region 3'UTR
Source ViRBase//VIRmiRNA//VmiReg Interactor1 expression None
Tissue or cell line BC-1 cells Interactor2 expression None
Description Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites.Clusters with seed matches to expressed miRNAs were considered candidate target sites. Of the clusters mapping to human 3'UTRs, 69% (BC-1) and 70% (BC-3) had seed matches to expressed miRNAs (Tables S6).Table S6A BC-1 derived 3'UTR clusters with seed matches to expressed miRNAs.

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