Basic Information:

  VIRBase ID:  

VHID00377080

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.9374

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART18-5p:  MIMAT0003717          LOC202181:  NR_026921     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART18-5p	LOC202181
miRBase Accession/Entrez ID	MIMAT0003717	202181
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	pseudo
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	LOC202181	chr5:177085838(-) A-I      intronic chr5:177086566(-) A-I      intronic chr5:177050621(-) A-I      intronic chr5:177050626(-) A-I      intronic chr5:177068157(-) A-I      intronic chr5:177068170(-) A-I      intronic chr5:177068203(-) A-I      intronic chr5:177084070(-) A-I      intronic chr5:177069391(-) A-I      intronic chr5:177071326(-) A-I      intronic chr5:177086527(-) A-I      intronic chr5:177085901(-) A-I      intronic chr5:177077703(-) A-I      intronic chr5:177085852(-) A-I      intronic chr5:177078194(-) A-I      intronic chr5:177078193(-) A-I      intronic chr5:177078164(-) A-I      intronic chr5:177078091(-) A-I      intronic chr5:177083939(-) A-I      intronic chr5:177083917(-) A-I      intronic chr5:177083869(-) A-I      intronic chr5:177083867(-) A-I      intronic chr5:177083862(-) A-I      intronic chr5:177083798(-) A-I      intronic chr5:177083776(-) A-I      intronic chr5:177078073(-) A-I      intronic chr5:177079782(-) A-I      intronic chr5:177078058(-) A-I      intronic chr5:177077773(-) A-I      intronic chr5:177077700(-) A-I      intronic chr5:177077684(-) A-I      intronic chr5:177077674(-) A-I      intronic chr5:177077664(-) A-I      intronic chr5:177050560(-) A-I      intronic chr5:177050597(-) A-I      intronic chr5:177050503(-) A-I      intronic chr5:177050506(-) A-I      intronic chr5:177050518(-) A-I      intronic chr5:177050555(-) A-I      intronic chr5:177079589(-) A-I      intronic chr5:177091527(-) A-I      intronic chr5:177091544(-) A-I      intronic chr5:177071330(-) A-I      intronic chr5:177049315(-) A-I      intronic chr5:177068148(-) A-I      intronic chr5:177068118(-) A-I      intronic chr5:177057672(-) A-I      intronic chr5:177050515(-) A-I      intronic chr5:177049354(-) A-I      intronic chr5:177049342(-) A-I      intronic chr5:177049328(-) A-I      intronic chr5:177049265(-) A-I      intronic chr5:177048248(-) A-I      intronic chr5:177083831(-) A-I      intronic chr5:177083804(-) A-I      intronic chr5:177083779(-) A-I      intronic chr5:177056087(-) A-I      intronic chr5:177056076(-) A-I      intronic chr5:177056058(-) A-I      intronic chr5:177050635(-) A-I      intronic chr5:177048138(-) A-I      intronic chr5:177051251(-) A-I      intronic chr5:177084201(-) A-I      intronic chr5:177048148(-) A-I      intronic chr5:177049428(-) A-I      intronic chr5:177082506(-) A-I      intronic chr5:177051151(-) A-I      intronic chr5:177050649(-) A-I      intronic chr5:177057060(-) A-I      intronic chr5:177049374(-) A-I      intronic chr5:177049327(-) A-I      intronic chr5:177049395(-) A-I      intronic chr5:177051210(-) A-I      intronic chr5:177082465(-) A-I      intronic chr5:177071358(-) A-I      intronic chr5:177049175(-) A-I      intronic chr5:177049384(-) A-I      intronic chr5:177086599(-) A-I      intronic chr5:177054924(-) A-I      intronic chr5:177049153(-) A-I      intronic chr5:177048152(-) A-I      intronic chr5:177056420(-) A-I      intronic chr5:177049240(-) A-I      intronic chr5:177050600(-) A-I      intronic chr5:177049214(-) A-I      intronic chr5:177049316(-) A-I      intronic chr5:177050627(-) A-I      intronic chr5:177083871(-) A-I      intronic chr5:177049202(-) A-I      intronic chr5:177049288(-) A-I      intronic chr5:177049292(-) A-I      intronic chr5:177048085(-) A-I      intronic chr5:177048070(-) A-I      intronic chr5:177048144(-) A-I      intronic chr5:177048095(-) A-I      intronic chr5:177085867(-) A-I      intronic chr5:177057704(-) A-I      intronic chr5:177049336(-) A-I      intronic chr5:177050509(-) A-I      intronic chr5:177049414(-) A-I      intronic chr5:177083870(-) A-I      intronic chr5:177048098(-) A-I      intronic chr5:177050438(-) A-I      intronic chr5:177048154(-) A-I      intronic chr5:177054788(-) A-I      intronic chr5:177086464(-) A-I      intronic chr5:177061250(-) A-I      intronic chr5:177049279(-) A-I      intronic chr5:177049324(-) A-I      intronic chr5:177086404(-) A-I      intronic chr5:177048105(-) A-I      intronic chr5:177085898(-) A-I      intronic chr5:177048137(-) A-I      intronic chr5:177094004(-) A-I      intronic chr5:177069384(-) A-I      intronic chr5:177049248(-) A-I      intronic chr5:177056288(-) A-I      intronic chr5:177048153(-) A-I      intronic chr5:177057076(-) A-I      intronic chr5:177056351(-) A-I      intronic chr5:177049308(-) A-I      intronic chr5:177054722(-) A-I      intronic chr5:177050562(-) A-I      intronic chr5:177069385(-) A-I      intronic chr5:177085829(-) A-I      intronic chr5:177050642(-) A-I      intronic chr5:177049296(-) A-I      intronic chr5:177091356(-) A-I      intronic chr5:177049311(-) A-I      intronic chr5:177049257(-) A-I      intronic chr5:177050573(-) A-I      intronic chr5:177048071(-) A-I      intronic chr5:177049389(-) A-I      intronic chr5:177058031(-) A-I      intronic chr5:177056056(-) A-I      intronic chr5:177049187(-) A-I      intronic chr5:177049373(-) A-I      intronic chr5:177085859(-) A-I      intronic chr5:177055922(-) A-I      intronic chr5:177082285(-) A-I      intronic chr5:177049181(-) A-I      intronic chr5:177080665(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	LOC202181	chr5:177048095(-) A-I intron -    15342557 chr5:177048145(-) A-I intron -    15342557 chr5:177048148(-) A-I intron -    15342557 chr5:177049175(-) A-I intron -    15342557   //22327324 chr5:177049181(-) A-I intron -    15342557 chr5:177049214(-) A-I intron -    15342557 chr5:177049248(-) A-I intron -    15342557 chr5:177049292(-) A-I intron -    15342557 chr5:177049296(-) A-I intron -    15342557 chr5:177049311(-) A-I intron -    15342557 chr5:177049316(-) A-I intron -    15342557 chr5:177049324(-) A-I intron -    15342557 chr5:177049353(-) A-I intron -    15342557 chr5:177049384(-) A-I intron -    15342557 chr5:177049395(-) A-I intron -    15342557 chr5:177049414(-) A-I intron -    15342557 chr5:177049422(-) A-I intron -    15342557 chr5:177085867(-) A-I intron -    22327324 chr5:177048144(-) A-G intron -    22484847 chr5:177048145(-) A-G intron -    22484847 chr5:177048148(-) A-G intron -    22484847 chr5:177048152(-) A-G intron -    22484847 chr5:177048154(-) A-G intron -    22484847 chr5:177049175(-) A-G intron -    22484847 chr5:177049181(-) A-G intron -    22484847 chr5:177049214(-) A-G intron -    22484847 chr5:177049215(-) A-G intron -    22484847 chr5:177049248(-) A-G intron -    22484847 chr5:177049292(-) A-G intron -    22484847 chr5:177049353(-) A-G intron -    22484847 chr5:177050509(-) A-G intron -    22484847 chr5:177050562(-) A-G intron -    22484847 chr5:177050600(-) A-G intron -    22484847 chr5:177050627(-) A-G intron -    22484847 chr5:177050642(-) A-G intron -    22484847 chr5:177050649(-) A-G intron -    22484847 chr5:177053355(-) A-G intron -    22484847 chr5:177056056(-) A-G intron -    22484847 chr5:177056420(-) A-G intron -    22484847 chr5:177057060(-) A-G intron -    22484847 chr5:177057076(-) A-G intron -    22484847 chr5:177069365(-) A-G intron -    22484847 chr5:177069384(-) A-G intron -    22484847 chr5:177069385(-) A-G intron -    22484847 chr5:177071358(-) A-G intron -    22484847 chr5:177082431(-) A-G intron -    22484847 chr5:177082495(-) A-G intron -    22484847 chr5:177084129(-) A-G intron -    22484847 chr5:177085867(-) A-G intron -    22484847 chr5:177086344(-) C-T intron -    22484847 chr5:177086464(-) A-G intron -    22484847 chr5:177086553(-) A-G intron -    22484847 chr5:177086596(-) A-G intron -    22484847 chr5:177086597(-) A-G intron -    22484847 chr5:177086599(-) A-G intron -    22484847

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART18-5p
Interactor2: LOC202181

Evidence Support:

Strong-Evidence	RT-PCR//Western blot
Weak-Evidence	Microarray
Support Database	VIRmiRNA

References:

PMID	25012295	Target region	3'UTR
Source	VIRmiRNA	Interactor1 expression	None
Tissue or cell line	BL2 cells//BJAB cells	Interactor2 expression	None
Description	BART 18-5p is one of the miRNAs that are abundantly expressed in latently infected resting memory B cells in vivo, with 300 copies per cell. Because EBV does not express any proteins in latently infected memory B cells, high levels of 18-5p expression may suggest a role for this miRNA in maintenance of viral latency. In this paper, we report on the identification of a target gene for 18-5p that implicates it in maintaining latency by suppressing viral replication.