Basic Information:

  VIRBase ID:  

VHID00372068

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART17-3p:  MIMAT0003716          MAPKAPK3:  NM_001243926     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART17-3p	MAPKAPK3
miRBase Accession/Entrez ID	MIMAT0003716	7867
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	3PK//MAPKAP-K3//MAPKAP3//MAPKAPK-3//MDPT3//MK-3//MK3

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MAPKAPK3	chr3:50673336(+) A-I      intronic chr3:50673335(+) A-I      intronic chr3:50673280(+) A-I      intronic chr3:50673281(+) A-I      intronic chr3:50673333(+) A-I      intronic chr3:50673328(+) A-I      intronic chr3:50673291(+) A-I      intronic chr3:50673028(+) A-I      intronic chr3:50673462(+) A-I      intronic chr3:50673318(+) A-I      intronic chr3:50673120(+) A-I      intronic chr3:50673276(+) A-I      intronic chr3:50658931(+) A-I      intronic chr3:50673412(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MAPKAPK3	chr3:50673028(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MAPKAPK3	chr3:50649076-50649077(+) m6A exon       24981863//27371828 chr3:50649113-50649114(+) m6A exon       24981863//27371828 chr3:50649142-50649143(+) m6A exon       24981863//27371828 chr3:50649530-50649531(+) m6A 5'UTR//exon       - chr3:50649801-50649802(+) m6A exon//intron       - chr3:50649809-50649810(+) m6A exon//intron       - chr3:50649862-50649863(+) m6A exon//intron       - chr3:50649888-50649889(+) m6A exon//intron       - chr3:50649954-50649955(+) m6A exon//intron       - chr3:50650018-50650019(+) m6A exon//intron       - chr3:50650077-50650078(+) m6A exon//intron       - chr3:50650104-50650105(+) m6A exon//intron       - chr3:50650123-50650124(+) m6A exon//intron       - chr3:50650331-50650332(+) m6A 5'UTR//exon       - chr3:50650338-50650339(+) m6A 5'UTR//exon       - chr3:50650351-50650352(+) m6A 5'UTR//exon       - chr3:50651230-50651231(+) m6A 5'UTR//exon       - chr3:50654920-50654921(+) m6A 5'UTR//intron       - chr3:50655008-50655009(+) m6A CDS       24981863 chr3:50655058-50655059(+) m6A CDS       - chr3:50685522-50685523(+) m6A 3'UTR       24284625//24981863//22608085 chr3:50685613-50685614(+) m6A 3'UTR       24284625//24981863//22608085 chr3:50685628-50685629(+) m6A 3'UTR       24284625//24981863//22608085 chr3:50685641-50685642(+) m6A 3'UTR       24284625//24981863//22608085 chr3:50686433-50686434(+) m6A 3'UTR       24284625 chr3:50686645-50686646(+) m6A 3'UTR       24284625 chr3:50686652-50686653(+) m6A 3'UTR       24284625

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MAPKAPK3	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART17-3p
Interactor2: MAPKAPK3

Evidence Support:

Prediction-Evidence	miRanda//PITA
Support Database	VmiReg