Basic Information:

  VIRBase ID:  

VHID00366515

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6061

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART17-5p:  MIMAT0003715          CSNK1A1:  NM_001892     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART17-5p	CSNK1A1
miRBase Accession/Entrez ID	MIMAT0003715	1452
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	CK1//CK1a//CKIa//HEL-S-77p//HLCDGP1//PRO2975

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CSNK1A1	chr5:148929719(-) A-I      NonSyn:Gln->Arg chr5:148929675(-) A-I      NonSyn:Lys->Glu chr5:148929674(-) A-I      NonSyn:Lys->Arg chr5:148929664(-) A-I      Syn:Gln->Gln chr5:148913933(-) A-I      intronic chr5:148913926(-) A-I      intronic chr5:148913910(-) A-I      intronic chr5:148912053(-) A-I      intronic chr5:148912011(-) A-I      intronic chr5:148911714(-) A-I      intronic chr5:148911708(-) A-I      intronic chr5:148911661(-) A-I      intronic chr5:148911659(-) A-I      intronic chr5:148911573(-) A-I      intronic chr5:148911552(-) A-I      intronic chr5:148911528(-) A-I      intronic chr5:148911519(-) A-I      intronic chr5:148911515(-) A-I      intronic chr5:148911507(-) A-I      intronic chr5:148910853(-) A-I      intronic chr5:148901924(-) A-I      intronic chr5:148901923(-) A-I      intronic chr5:148890832(-) A-I      intronic chr5:148890709(-) A-I      intronic chr5:148890672(-) A-I      intronic chr5:148890188(-) A-I      intronic chr5:148890180(-) A-I      intronic chr5:148925541(-) A-I      intronic chr5:148922530(-) A-I      intronic chr5:148920947(-) A-I      intronic chr5:148889979(-) A-I      intronic chr5:148879157(-) A-I      intronic chr5:148920864(-) A-I      intronic chr5:148879153(-) A-I      intronic chr5:148879142(-) A-I      intronic chr5:148879081(-) A-I      intronic chr5:148879068(-) A-I      intronic chr5:148879055(-) A-I      intronic chr5:148927707(-) A-I      intronic chr5:148927702(-) A-I      intronic chr5:148927680(-) A-I      intronic chr5:148927665(-) A-I      intronic chr5:148927658(-) A-I      intronic chr5:148925738(-) A-I      intronic chr5:148925941(-) A-I      intronic chr5:148926030(-) A-I      intronic chr5:148926032(-) A-I      intronic chr5:148927627(-) A-I      intronic chr5:148928030(-) A-I      intronic chr5:148928099(-) A-I      intronic chr5:148928180(-) A-I      intronic chr5:148928207(-) A-I      intronic chr5:148925737(-) A-I      intronic chr5:148925732(-) A-I      intronic chr5:148925707(-) A-I      intronic chr5:148925697(-) A-I      intronic chr5:148925692(-) A-I      intronic chr5:148928365(-) A-I      intronic chr5:148928312(-) A-I      intronic chr5:148928300(-) A-I      intronic chr5:148928288(-) A-I      intronic chr5:148928277(-) A-I      intronic chr5:148927684(-) A-I      intronic chr5:148927676(-) A-I      intronic chr5:148925573(-) A-I      intronic chr5:148925509(-) A-I      intronic chr5:148925504(-) A-I      intronic chr5:148925499(-) A-I      intronic chr5:148925489(-) A-I      intronic chr5:148927598(-) A-I      intronic chr5:148927582(-) A-I      intronic chr5:148927566(-) A-I      intronic chr5:148927572(-) A-I      intronic chr5:148927571(-) A-I      intronic chr5:148890695(-) A-I      intronic chr5:148927562(-) A-I      intronic chr5:148927548(-) A-I      intronic chr5:148927545(-) A-I      intronic chr5:148927539(-) A-I      intronic chr5:148927531(-) A-I      intronic chr5:148926158(-) A-I      intronic chr5:148926134(-) A-I      intronic chr5:148926110(-) A-I      intronic chr5:148926109(-) A-I      intronic chr5:148890684(-) A-I      intronic chr5:148890644(-) A-I      intronic chr5:148880219(-) A-I      intronic chr5:148920580(-) A-I      intronic chr5:148926084(-) A-I      intronic chr5:148925576(-) A-I      intronic chr5:148920531(-) A-I      intronic chr5:148920524(-) A-I      intronic chr5:148920456(-) A-I      intronic chr5:148925549(-) A-I      intronic chr5:148920449(-) A-I      intronic chr5:148919031(-) A-I      intronic chr5:148918996(-) A-I      intronic chr5:148918929(-) A-I      intronic chr5:148918858(-) A-I      intronic chr5:148918373(-) A-I      intronic chr5:148918855(-) A-I      intronic chr5:148918441(-) A-I      intronic chr5:148918403(-) A-I      intronic chr5:148910923(-) A-I      intronic chr5:148918366(-) A-I      intronic chr5:148918241(-) A-I      intronic chr5:148916817(-) A-I      intronic chr5:148916804(-) A-I      intronic chr5:148916736(-) A-I      intronic chr5:148916721(-) A-I      intronic chr5:148916704(-) A-I      intronic chr5:148915641(-) A-I      intronic chr5:148915614(-) A-I      intronic chr5:148915609(-) A-I      intronic chr5:148915607(-) A-I      intronic chr5:148915555(-) A-I      intronic chr5:148915481(-) A-I      intronic chr5:148915412(-) A-I      intronic chr5:148915405(-) A-I      intronic chr5:148915391(-) A-I      intronic chr5:148925276(-) A-I      intronic chr5:148915238(-) A-I      intronic chr5:148872743(-) A-I      3'UTR chr5:148872807(-) A-I      3'UTR chr5:148920751(-) A-I      intronic chr5:148926033(-) A-I      intronic chr5:148921007(-) A-I      intronic chr5:148915602(-) A-I      intronic chr5:148890261(-) A-I      intronic chr5:148890671(-) A-I      intronic chr5:148925954(-) A-I      intronic chr5:148923393(-) A-I      intronic chr5:148920461(-) A-I      intronic chr5:148915692(-) A-I      intronic chr5:148923369(-) A-I      intronic chr5:148928417(-) A-I      intronic chr5:148925519(-) A-I      intronic chr5:148911245(-) A-I      intronic chr5:148926072(-) A-I      intronic chr5:148911721(-) A-I      intronic chr5:148890206(-) A-I      intronic chr5:148925729(-) A-I      intronic chr5:148927706(-) A-I      intronic chr5:148915619(-) A-I      intronic chr5:148928355(-) A-I      intronic chr5:148915693(-) A-I      intronic chr5:148890318(-) A-I      intronic chr5:148915436(-) A-I      intronic chr5:148925520(-) A-I      intronic chr5:148926127(-) A-I      intronic chr5:148911018(-) A-I      intronic chr5:148879080(-) A-I      intronic chr5:148916827(-) A-I      intronic chr5:148920521(-) A-I      intronic chr5:148879133(-) A-I      intronic chr5:148921373(-) A-I      intronic chr5:148880242(-) A-I      intronic chr5:148913995(-) A-I      intronic chr5:148928349(-) A-I      intronic chr5:148917857(-) A-I      intronic chr5:148918294(-) A-I      intronic chr5:148911688(-) A-I      intronic chr5:148927701(-) A-I      intronic chr5:148920413(-) A-I      intronic chr5:148889947(-) A-I      intronic chr5:148927885(-) A-I      intronic chr5:148890849(-) A-I      intronic chr5:148915316(-) A-I      intronic chr5:148920655(-) A-I      intronic chr5:148872798(-) A-I      3'UTR chr5:148872853(-) A-I      3'UTR chr5:148872802(-) A-I      3'UTR chr5:148872758(-) A-I      3'UTR chr5:148872833(-) A-I      3'UTR chr5:148872828(-) A-I      3'UTR chr5:148872852(-) A-I      3'UTR chr5:148872771(-) A-I      3'UTR chr5:148872745(-) A-I      3'UTR chr5:148872739(-) A-I      3'UTR chr5:148872838(-) A-I      3'UTR chr5:148872837(-) A-I      3'UTR chr5:148872811(-) A-I      3'UTR chr5:148872710(-) A-I      3'UTR chr5:148872772(-) A-I      3'UTR chr5:148872014(-) A-I      3'UTR chr5:148872810(-) A-I      3'UTR chr5:148872723(-) A-I      3'UTR chr5:148872730(-) A-I      3'UTR chr5:148872742(-) A-I      3'UTR chr5:148872749(-) A-I      3'UTR chr5:148872701(-) A-I      3'UTR chr5:148879090(-) A-I      intronic chr5:148890641(-) A-I      intronic chr5:148922537(-) A-I      intronic chr5:148928290(-) A-I      intronic chr5:148928329(-) A-I      intronic chr5:148879152(-) A-I      intronic chr5:148915780(-) A-I      intronic chr5:148890203(-) A-I      intronic chr5:148914250(-) A-I      intronic chr5:148889986(-) A-I      intronic chr5:148915290(-) A-I      intronic chr5:148926074(-) A-I      intronic chr5:148879160(-) A-I      intronic chr5:148915446(-) A-I      intronic chr5:148890837(-) A-I      intronic chr5:148923335(-) A-I      intronic chr5:148921418(-) A-I      intronic chr5:148915495(-) A-I      intronic chr5:148913961(-) A-I      intronic chr5:148915789(-) A-I      intronic chr5:148915681(-) A-I      intronic chr5:148927507(-) A-I      intronic chr5:148928416(-) A-I      intronic chr5:148879074(-) A-I      intronic chr5:148912134(-) A-I      intronic chr5:148912005(-) A-I      intronic chr5:148913788(-) A-I      intronic chr5:148880257(-) A-I      intronic chr5:148880234(-) A-I      intronic chr5:148890088(-) A-I      intronic chr5:148879107(-) A-I      intronic chr5:148926150(-) A-I      intronic chr5:148920813(-) A-I      intronic chr5:148925590(-) A-I      intronic chr5:148927964(-) A-I      intronic chr5:148928330(-) A-I      intronic chr5:148920727(-) A-I      intronic chr5:148920472(-) A-I      intronic chr5:148920821(-) A-I      intronic chr5:148911228(-) A-I      intronic chr5:148911514(-) A-I      intronic chr5:148920853(-) A-I      intronic chr5:148914346(-) A-I      intronic chr5:148926087(-) A-I      intronic chr5:148914359(-) A-I      intronic chr5:148889989(-) A-I      intronic chr5:148928167(-) A-I      intronic chr5:148927537(-) A-I      intronic chr5:148890260(-) A-I      intronic chr5:148911544(-) A-I      intronic chr5:148912020(-) A-I      intronic chr5:148914249(-) A-I      intronic chr5:148921366(-) A-I      intronic chr5:148890826(-) A-I      intronic chr5:148890138(-) A-I      intronic chr5:148921322(-) A-I      intronic chr5:148927653(-) A-I      intronic chr5:148914298(-) A-I      intronic chr5:148915369(-) A-I      intronic chr5:148911619(-) A-I      intronic chr5:148879967(-) A-I      intronic chr5:148927685(-) A-I      intronic chr5:148920399(-) A-I      intronic chr5:148911693(-) A-I      intronic chr5:148918337(-) A-I      intronic chr5:148928054(-) A-I      intronic chr5:148925484(-) A-I      intronic chr5:148928368(-) A-I      intronic chr5:148926113(-) A-I      intronic chr5:148911312(-) A-I      intronic chr5:148923463(-) A-I      intronic chr5:148928161(-) A-I      intronic chr5:148915589(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CSNK1A1	chr5:148879074(-) A-I intron -    21960545   //22327324 chr5:148879107(-) A-I intron -    21960545 chr5:148880242(-) A-I intron -    21960545 chr5:148875327(-) C-T exon 3'UTR    21725310 chr5:148877575(-) T-A intron -    22484847 chr5:148877638(-) T-G intron -    22484847 chr5:148879074(-) A-G intron -    22484847 chr5:148879967(-) A-G intron -    22484847 chr5:148880242(-) A-G intron -    22484847 chr5:148880257(-) A-G intron -    22484847 chr5:148882418(-) T-C intron -    22484847 chr5:148882435(-) T-G intron -    22484847 chr5:148882512(-) A-T intron -    22484847 chr5:148888661(-) G-A intron -    22484847 chr5:148890203(-) A-G intron -    22484847 chr5:148890837(-) A-G intron -    22484847 chr5:148911228(-) A-G intron -    22484847 chr5:148911245(-) A-G intron -    22484847 chr5:148911269(-) T-G intron -    22484847 chr5:148911270(-) T-G intron -    22484847 chr5:148911271(-) G-T intron -    22484847 chr5:148911276(-) T-G intron -    22484847 chr5:148911278(-) G-T intron -    22484847 chr5:148911688(-) A-G intron -    22484847 chr5:148911692(-) A-G intron -    22484847 chr5:148911693(-) A-G intron -    22484847 chr5:148911701(-) A-G intron -    22484847 chr5:148911721(-) A-G intron -    22484847 chr5:148912005(-) A-G intron -    22484847 chr5:148912090(-) A-G intron -    22484847 chr5:148912093(-) A-G intron -    22484847 chr5:148912134(-) A-G intron -    22484847 chr5:148913961(-) A-G intron -    22484847 chr5:148913995(-) A-G intron -    22484847 chr5:148914249(-) A-G intron -    22484847 chr5:148914250(-) A-G intron -    22484847 chr5:148915208(-) G-C intron -    22484847 chr5:148915316(-) A-G intron -    22484847 chr5:148915356(-) A-G intron -    22484847 chr5:148915681(-) A-G intron -    22484847 chr5:148915780(-) A-G intron -    22484847 chr5:148916827(-) A-G intron -    22484847 chr5:148918268(-) A-G intron -    22484847 chr5:148918294(-) A-G intron -    22484847 chr5:148918314(-) G-A intron -    22484847 chr5:148918337(-) A-G intron -    22484847 chr5:148918402(-) A-G intron -    22484847 chr5:148920413(-) A-G intron -    22484847 chr5:148920461(-) A-G intron -    22484847 chr5:148920853(-) A-G intron -    22484847 chr5:148921007(-) A-G intron -    22484847 chr5:148921322(-) A-G intron -    22484847 chr5:148921366(-) A-G intron -    22484847 chr5:148921418(-) A-G intron -    22484847 chr5:148923393(-) A-G intron -    22484847 chr5:148923454(-) T-G intron -    22484847 chr5:148924071(-) A-T intron -    22484847 chr5:148924072(-) A-T intron -    22484847 chr5:148925484(-) A-G intron -    22484847 chr5:148925519(-) A-G intron -    22484847 chr5:148925520(-) A-G intron -    22484847 chr5:148925563(-) A-G intron -    22484847 chr5:148925580(-) A-G intron -    22484847 chr5:148925590(-) A-G intron -    22484847 chr5:148925729(-) A-G intron -    22484847 chr5:148925953(-) A-G intron -    22484847 chr5:148925954(-) A-G intron -    22484847 chr5:148926068(-) A-G intron -    22484847 chr5:148926072(-) A-G intron -    22484847 chr5:148926074(-) A-G intron -    22484847 chr5:148926087(-) A-G intron -    22484847 chr5:148926113(-) A-G intron -    22484847 chr5:148926114(-) A-G intron -    22484847 chr5:148926127(-) A-G intron -    22484847 chr5:148926150(-) A-G intron -    22484847 chr5:148927530(-) A-G intron -    22484847 chr5:148927653(-) A-G intron -    22484847 chr5:148927661(-) A-G intron -    22484847 chr5:148927685(-) A-G intron -    22484847 chr5:148927701(-) A-G intron -    22484847 chr5:148927895(-) A-G intron -    22484847 chr5:148928290(-) A-G intron -    22484847 chr5:148928330(-) A-G intron -    22484847 chr5:148928417(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CSNK1A1	chr5:148872559-148872560(-) m6A 3'UTR       27773535 chr5:148872660-148872661(-) m6A 3'UTR       24981863//27773535 chr5:148872729-148872730(-) m6A 3'UTR       24981863 chr5:148872826-148872827(-) m6A 3'UTR       27773535//22608085 chr5:148872849-148872850(-) m6A 3'UTR       24284625//27773535//22608085 chr5:148872976-148872977(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085 chr5:148872983-148872984(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085 chr5:148873037-148873038(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085 chr5:148873050-148873051(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085 chr5:148873096-148873097(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr5:148873148-148873149(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr5:148873168-148873169(-) m6A 3'UTR       24981863//27773535//22608085 chr5:148873893-148873894(-) m6A 3'UTR       27773535 chr5:148874042-148874043(-) m6A 3'UTR       24981863//27773535 chr5:148874082-148874083(-) m6A 3'UTR       24981863//27773535 chr5:148874105-148874106(-) m6A 3'UTR       24981863//27773535 chr5:148875675-148875676(-) m6A 3'UTR//CDS       - chr5:148875758-148875759(-) m6A 3'UTR//5'UTR       24284625//24981863//22608085 chr5:148875786-148875787(-) m6A 3'UTR//5'UTR       24284625//24981863//22575960//22608085 chr5:148875797-148875798(-) m6A 3'UTR//5'UTR       24284625//24981863//22575960//22608085 chr5:148875844-148875845(-) m6A 3'UTR//5'UTR       24284625//24981863//22575960//22608085 chr5:148875928-148875929(-) m6A 3'UTR//5'UTR       24284625//24981863//22575960//22608085 chr5:148876025-148876026(-) m6A 3'UTR//5'UTR       24284625 chr5:148876066-148876067(-) m6A 3'UTR//5'UTR       24284625 chr5:148876188-148876189(-) m6A 3'UTR//5'UTR       24284625//24981863//22575960//22608085 chr5:148876267-148876268(-) m6A 3'UTR//5'UTR       24284625//24981863//22575960//22608085 chr5:148876284-148876285(-) m6A 3'UTR//5'UTR       24284625//24981863//22575960//22608085 chr5:148876308-148876309(-) m6A 3'UTR//intron       24284625//24981863//22608085 chr5:148876400-148876401(-) m6A 3'UTR//intron       24981863//22608085 chr5:148877195-148877196(-) m6A intron       27773535 chr5:148877278-148877279(-) m6A intron       27773535 chr5:148877343-148877344(-) m1A intron       26863196 chr5:148877361-148877362(-) m6A intron       27773535 chr5:148877396-148877397(-) m6A intron       24981863//27773535 chr5:148877423-148877424(-) m6A intron       24981863//27773535//27371828 chr5:148877492-148877493(-) m6A intron       24981863//27773535 chr5:148878509-148878510(-) m6A intron       24284625//27773535//22608085 chr5:148878640-148878641(-) m6A intron       24284625//24981863//26404942//27773535//27371828//22575960//22608085 chr5:148878663-148878664(-) m6A intron       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085 chr5:148878708-148878709(-) m6A intron       24284625//24209618//24981863//27773535//27371828//22575960//22608085 chr5:148878748-148878749(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//27371828//22575960//22608085 chr5:148878755-148878756(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//27371828//22575960//22608085 chr5:148878790-148878791(-) Am 3'UTR//intron       - chr5:148878798-148878799(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr5:148880580-148880581(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085 chr5:148880614-148880615(-) m6A 3'UTR//intron       27773535//22608085 chr5:148880661-148880662(-) m6A 3'UTR//intron       27773535//22608085 chr5:148880717-148880718(-) m6A 5'UTR//CDS//intron       24284625//27773535//22608085 chr5:148880725-148880726(-) m6A 5'UTR//CDS//intron       24284625//27773535//22608085 chr5:148880819-148880820(-) m6A intron       24284625//25456834//24981863//27773535//27371828//22575960//22608085 chr5:148880874-148880875(-) m6A intron       24284625//25456834//24981863//27773535//27371828//22575960//22608085 chr5:148880917-148880918(-) m6A intron       24284625//24981863//27773535//27371828//22575960//22608085 chr5:148880926-148880927(-) m6A intron       24284625//24981863//27773535//27371828//22575960//22608085 chr5:148881152-148881153(-) m6A intron       27773535 chr5:148884523-148884524(-) m6A 3'UTR//intron       25456834//27773535 chr5:148925058-148925059(-) m6A intron       27371828 chr5:148925133-148925134(-) m6A intron       27773535//27371828 chr5:148930438-148930439(-) m6A CDS       27773535 chr5:148930463-148930464(-) Am CDS       - chr5:148930473-148930474(-) m6A CDS       24284625//27773535 chr5:148930662-148930663(-) m6A 5'UTR       24284625//25456834//27371828//27773536//22575960 chr5:148930714-148930715(-) m6A 5'UTR       24284625//25456834//24981863//27371828//27773536//22575960 chr5:148930735-148930736(-) m6A 5'UTR       24284625//25456834//24981863//27371828//27773536//22575960 chr5:148930777-148930778(-) m6A 5'UTR       24284625//25456834//24981863//27371828//27773536//22575960//22608085 chr5:148930962-148930963(-) m6A 5'UTR       24284625//24981863//27371828//27773536//22608085 chr5:148930977-148930978(-) m1A 5'UTR       26863196//26863410

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	CSNK1A1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART17-5p
Interactor2: CSNK1A1

Evidence Support:

Weak-Evidence	PAR-CLIP
Prediction-Evidence	cRep//miRanda//PARalyzer//PITA//RNAHybrid//Targetscan
Support Database	RepTar//ViRBase//VmiReg

References:

PMID	22100165	Target region	3'UTR
Source	RepTar//ViRBase//VmiReg	Interactor1 expression	None
Tissue or cell line	BC-1 cells	Interactor2 expression	None
Description	Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites.Clusters with seed matches to expressed miRNAs were considered candidate target sites. Of the clusters mapping to human 3'UTRs, 69% (BC-1) and 70% (BC-3) had seed matches to expressed miRNAs (Tables S6).Table S6A BC-1 derived 3'UTR clusters with seed matches to expressed miRNAs.