Basic Information:

  VIRBase ID:  

VHID00363492

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART16:  MIMAT0003714          TRIM35:  NM_171982     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART16	TRIM35
miRBase Accession/Entrez ID	MIMAT0003714	23087
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	HLS5//MAIR

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TRIM35	chr8:27147948(-) A-I      intronic chr8:27147983(-) A-I      intronic chr8:27147969(-) A-I      intronic chr8:27149440(-) A-I      intronic chr8:27147963(-) A-I      intronic chr8:27147974(-) A-I      intronic chr8:27163451(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	TRIM35	chr8:27148107(-) A-I intron -    22327324 chr8:27148134(-) A-I intron -    22327324 chr8:27148181(-) A-I intron -    22327324 chr8:27149263(-) A-I intron -    22327324 chr8:27149293(-) A-I intron -    22327324 chr8:27147960(-) A-G intron -    22484847 chr8:27147971(-) A-G intron -    22484847 chr8:27148007(-) A-G intron -    22484847 chr8:27148009(-) A-G intron -    22484847 chr8:27148107(-) A-G intron -    22484847 chr8:27148134(-) A-G intron -    22484847 chr8:27148181(-) A-G intron -    22484847 chr8:27149263(-) A-G intron -    22484847 chr8:27149293(-) A-G intron -    22484847 chr8:27149420(-) A-G intron -    22484847 chr8:27149448(-) A-G intron -    22484847 chr8:27149490(-) A-G intron -    22484847 chr8:27149491(-) A-G intron -    22484847 chr8:27149534(-) A-G intron -    22484847 chr8:27149561(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TRIM35	chr8:27143282-27143283(-) m6A 3'UTR       27773535 chr8:27143561-27143562(-) m6A 3'UTR       24981863 chr8:27144533-27144534(-) m6A 3'UTR//intron       24981863 chr8:27144586-27144587(-) m6A 3'UTR//intron       24981863 chr8:27144699-27144700(-) m6A 3'UTR//intron       24981863 chr8:27145078-27145079(-) m6A CDS//intron       24284625 chr8:27145307-27145308(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr8:27145325-27145326(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr8:27145415-27145416(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr8:27145544-27145545(-) m6A 3'UTR//CDS//intron       24284625//27371828//22608085 chr8:27147692-27147693(-) m6A CDS//intron       27371828//27773536 chr8:27151721-27151722(-) m6A CDS//exon       24981863//27773535//27371828//27773536 chr8:27156062-27156063(-) m6A CDS//exon//intron       27371828//27773536 chr8:27168336-27168337(-) m6A CDS//exon       27371828//27773536 chr8:27168408-27168409(-) m6A CDS       24284625//27371828//27773536 chr8:27168434-27168435(-) m6A CDS       24284625//27371828//27773536 chr8:27168475-27168476(-) m6A CDS       24284625//27371828//27773536 chr8:27168567-27168568(-) m6A CDS       24284625//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	TRIM35	Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352 Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART16
Interactor2: TRIM35

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA
Support Database	RepTar//VmiReg