Basic Information:

  VIRBase ID:  

VHID00342593

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2202

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART12:  MIMAT0003423          ROCK1:  NM_005406     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART12	ROCK1
miRBase Accession/Entrez ID	MIMAT0003423	6093
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	P160ROCK//ROCK-I

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ROCK1	chr18:18553936(-) A-I      intronic chr18:18559328(-) A-I      intronic chr18:18559366(-) A-I      intronic chr18:18566027(-) A-I      intronic chr18:18599191(-) A-I      intronic chr18:18599226(-) A-I      intronic chr18:18599309(-) A-I      intronic chr18:18607104(-) A-I      intronic chr18:18647512(-) A-I      intronic chr18:18647517(-) A-I      intronic chr18:18647526(-) A-I      intronic chr18:18559340(-) A-I      intronic chr18:18559380(-) A-I      intronic chr18:18559364(-) A-I      intronic chr18:18559378(-) A-I      intronic chr18:18566032(-) A-I      intronic chr18:18566030(-) A-I      intronic chr18:18553911(-) A-I      intronic chr18:18553926(-) A-I      intronic chr18:18553934(-) A-I      intronic chr18:18612710(-) A-I      intronic chr18:18612660(-) A-I      intronic chr18:18612613(-) A-I      intronic chr18:18684369(-) A-I      intronic chr18:18608291(-) A-I      intronic chr18:18608255(-) A-I      intronic chr18:18608237(-) A-I      intronic chr18:18607927(-) A-I      intronic chr18:18683678(-) A-I      intronic chr18:18607861(-) A-I      intronic chr18:18607851(-) A-I      intronic chr18:18607819(-) A-I      intronic chr18:18607780(-) A-I      intronic chr18:18607195(-) A-I      intronic chr18:18607155(-) A-I      intronic chr18:18607150(-) A-I      intronic chr18:18607142(-) A-I      intronic chr18:18607918(-) A-I      intronic chr18:18607127(-) A-I      intronic chr18:18607094(-) A-I      intronic chr18:18607068(-) A-I      intronic chr18:18607064(-) A-I      intronic chr18:18607038(-) A-I      intronic chr18:18607037(-) A-I      intronic chr18:18607028(-) A-I      intronic chr18:18606962(-) A-I      intronic chr18:18606947(-) A-I      intronic chr18:18606938(-) A-I      intronic chr18:18605563(-) A-I      intronic chr18:18599715(-) A-I      intronic chr18:18599696(-) A-I      intronic chr18:18599647(-) A-I      intronic chr18:18683576(-) A-I      intronic chr18:18683558(-) A-I      intronic chr18:18683527(-) A-I      intronic chr18:18682587(-) A-I      intronic chr18:18638646(-) A-I      intronic chr18:18638764(-) A-I      intronic chr18:18638786(-) A-I      intronic chr18:18679539(-) A-I      intronic chr18:18679494(-) A-I      intronic chr18:18638804(-) A-I      intronic chr18:18640584(-) A-I      intronic chr18:18640754(-) A-I      intronic chr18:18641177(-) A-I      intronic chr18:18641178(-) A-I      intronic chr18:18641180(-) A-I      intronic chr18:18669131(-) A-I      intronic chr18:18668433(-) A-I      intronic chr18:18668359(-) A-I      intronic chr18:18658288(-) A-I      intronic chr18:18658142(-) A-I      intronic chr18:18658107(-) A-I      intronic chr18:18658105(-) A-I      intronic chr18:18652877(-) A-I      intronic chr18:18652852(-) A-I      intronic chr18:18559162(-) A-I      intronic chr18:18555807(-) A-I      intronic chr18:18551550(-) A-I      intronic chr18:18684526(-) A-I      intronic chr18:18627757(-) A-I      intronic chr18:18628783(-) A-I      intronic chr18:18627755(-) A-I      intronic chr18:18627565(-) A-I      intronic chr18:18626879(-) A-I      intronic chr18:18599637(-) A-I      intronic chr18:18599334(-) A-I      intronic chr18:18599320(-) A-I      intronic chr18:18599144(-) A-I      intronic chr18:18598434(-) A-I      intronic chr18:18598391(-) A-I      intronic chr18:18598379(-) A-I      intronic chr18:18598261(-) A-I      intronic chr18:18597887(-) A-I      intronic chr18:18597882(-) A-I      intronic chr18:18597872(-) A-I      intronic chr18:18597777(-) A-I      intronic chr18:18597704(-) A-I      intronic chr18:18597385(-) A-I      intronic chr18:18597380(-) A-I      intronic chr18:18597349(-) A-I      intronic chr18:18597342(-) A-I      intronic chr18:18597291(-) A-I      intronic chr18:18597258(-) A-I      intronic chr18:18597242(-) A-I      intronic chr18:18597205(-) A-I      intronic chr18:18597188(-) A-I      intronic chr18:18585794(-) A-I      intronic chr18:18585752(-) A-I      intronic chr18:18582980(-) A-I      intronic chr18:18582862(-) A-I      intronic chr18:18582817(-) A-I      intronic chr18:18612952(-) A-I      intronic chr18:18580510(-) A-I      intronic chr18:18580505(-) A-I      intronic chr18:18580503(-) A-I      intronic chr18:18574507(-) A-I      intronic chr18:18574383(-) A-I      intronic chr18:18574378(-) A-I      intronic chr18:18574360(-) A-I      intronic chr18:18573382(-) A-I      intronic chr18:18573302(-) A-I      intronic chr18:18573275(-) A-I      intronic chr18:18570914(-) A-I      intronic chr18:18570860(-) A-I      intronic chr18:18570850(-) A-I      intronic chr18:18570833(-) A-I      intronic chr18:18570818(-) A-I      intronic chr18:18570730(-) A-I      intronic chr18:18641239(-) A-I      intronic chr18:18641259(-) A-I      intronic chr18:18651278(-) A-I      intronic chr18:18651433(-) A-I      intronic chr18:18570555(-) A-I      intronic chr18:18566022(-) A-I      intronic chr18:18564871(-) A-I      intronic chr18:18561237(-) A-I      intronic chr18:18560777(-) A-I      intronic chr18:18560688(-) A-I      intronic chr18:18608333(-) A-I      intronic chr18:18597397(-) A-I      intronic chr18:18553434(-) A-I      intronic chr18:18597446(-) A-I      intronic chr18:18565989(-) A-I      intronic chr18:18612655(-) A-I      intronic chr18:18574338(-) A-I      intronic chr18:18597769(-) A-I      intronic chr18:18612961(-) A-I      intronic chr18:18668309(-) A-I      intronic chr18:18599757(-) A-I      intronic chr18:18612665(-) A-I      intronic chr18:18605530(-) A-I      intronic chr18:18608294(-) A-I      intronic chr18:18638679(-) A-I      intronic chr18:18553112(-) A-I      intronic chr18:18597333(-) A-I      intronic chr18:18597354(-) A-I      intronic chr18:18668308(-) A-I      intronic chr18:18608331(-) A-I      intronic chr18:18637591(-) A-I      intronic chr18:18599335(-) A-I      intronic chr18:18597920(-) A-I      intronic chr18:18628625(-) A-I      intronic chr18:18627633(-) A-I      intronic chr18:18605532(-) A-I      intronic chr18:18566094(-) A-I      intronic chr18:18582826(-) A-I      intronic chr18:18597822(-) A-I      intronic chr18:18612750(-) A-I      intronic chr18:18565891(-) A-I      intronic chr18:18605664(-) A-I      intronic chr18:18599182(-) A-I      intronic chr18:18670324(-) A-I      intronic chr18:18597812(-) A-I      intronic chr18:18564951(-) A-I      intronic chr18:18582795(-) A-I      intronic chr18:18599145(-) A-I      intronic chr18:18574494(-) A-I      intronic chr18:18570572(-) A-I      intronic chr18:18561188(-) A-I      intronic chr18:18599304(-) A-I      intronic chr18:18597785(-) A-I      intronic chr18:18599565(-) A-I      intronic chr18:18668267(-) A-I      intronic chr18:18580326(-) A-I      intronic chr18:18598409(-) A-I      intronic chr18:18592073(-) A-I      intronic chr18:18668237(-) A-I      intronic chr18:18574423(-) A-I      intronic chr18:18641273(-) A-I      intronic chr18:18599253(-) A-I      intronic chr18:18607077(-) A-I      intronic chr18:18597668(-) A-I      intronic chr18:18597317(-) A-I      intronic chr18:18598428(-) A-I      intronic chr18:18593970(-) A-I      intronic chr18:18605460(-) A-I      intronic chr18:18597253(-) A-I      intronic chr18:18605614(-) A-I      intronic chr18:18566046(-) A-I      intronic chr18:18640756(-) A-I      intronic chr18:18577926(-) A-I      intronic chr18:18570483(-) A-I      intronic chr18:18638681(-) A-I      intronic chr18:18559163(-) A-I      intronic chr18:18608122(-) A-I      intronic chr18:18570903(-) A-I      intronic chr18:18683512(-) A-I      intronic chr18:18607076(-) A-I      intronic chr18:18598369(-) A-I      intronic chr18:18641215(-) A-I      intronic chr18:18607126(-) A-I      intronic chr18:18598408(-) A-I      intronic chr18:18640678(-) A-I      intronic chr18:18628639(-) A-I      intronic chr18:18564999(-) A-I      intronic chr18:18573328(-) A-I      intronic chr18:18670261(-) A-I      intronic chr18:18683679(-) A-I      intronic chr18:18656277(-) A-I      intronic chr18:18647620(-) A-I      intronic chr18:18570899(-) A-I      intronic chr18:18641330(-) A-I      intronic chr18:18588373(-) A-I      intronic chr18:18627668(-) A-I      intronic chr18:18669157(-) A-I      intronic chr18:18682679(-) A-I      intronic chr18:18598429(-) A-I      intronic chr18:18605535(-) A-I      intronic chr18:18682678(-) A-I      intronic chr18:18574465(-) A-I      intronic chr18:18597249(-) A-I      intronic chr18:18564818(-) A-I      intronic chr18:18641213(-) A-I      intronic chr18:18597250(-) A-I      intronic chr18:18559141(-) A-I      intronic chr18:18605683(-) A-I      intronic chr18:18593833(-) A-I      intronic chr18:18597689(-) A-I      intronic chr18:18670312(-) A-I      intronic chr18:18597766(-) A-I      intronic chr18:18570881(-) A-I      intronic chr18:18565984(-) A-I      intronic chr18:18598455(-) A-I      intronic chr18:18627720(-) A-I      intronic chr18:18561166(-) A-I      intronic chr18:18561243(-) A-I      intronic chr18:18585602(-) A-I      intronic chr18:18670277(-) A-I      intronic chr18:18573434(-) A-I      intronic chr18:18640598(-) A-I      intronic chr18:18573435(-) A-I      intronic chr18:18669288(-) A-I      intronic chr18:18581560(-) A-I      intronic chr18:18628749(-) A-I      intronic chr18:18597677(-) A-I      intronic chr18:18597424(-) A-I      intronic chr18:18561191(-) A-I      intronic chr18:18606967(-) A-I      intronic chr18:18612596(-) A-I      intronic chr18:18562492(-) A-I      intronic chr18:18577922(-) A-I      intronic chr18:18562351(-) A-I      intronic chr18:18599279(-) A-I      intronic chr18:18574402(-) A-I      intronic chr18:18561246(-) A-I      intronic chr18:18599175(-) A-I      intronic chr18:18641268(-) A-I      intronic chr18:18638777(-) A-I      intronic chr18:18673728(-) A-I      intronic chr18:18560765(-) A-I      intronic chr18:18597661(-) A-I      intronic chr18:18599200(-) A-I      intronic chr18:18599298(-) A-I      intronic chr18:18573269(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ROCK1	chr18:18599145(-) A-I intron -    22327324 chr18:18573434(-) A-G intron -    22484847 chr18:18573435(-) A-G intron -    22484847 chr18:18588520(-) A-G intron -    22484847 chr18:18597766(-) A-G intron -    22484847 chr18:18599145(-) A-G intron -    22484847 chr18:18599153(-) G-A intron -    22484847 chr18:18640748(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ROCK1	chr18:18530588-18530589(-) m6A 3'UTR       24981863//27773535 chr18:18530605-18530606(-) m6A 3'UTR       24981863//27773535 chr18:18530615-18530616(-) m6A 3'UTR       24981863//27773535 chr18:18530682-18530683(-) m6A 3'UTR       24981863//27773535//22608085 chr18:18530764-18530765(-) m6A 3'UTR       24981863//27773535//22608085 chr18:18530820-18530821(-) m6A 3'UTR       24981863//27773535//22608085 chr18:18530851-18530852(-) m6A 3'UTR       24981863//27773535//22608085 chr18:18530861-18530862(-) m6A 3'UTR       24981863//27773535//22608085 chr18:18530916-18530917(-) m6A 3'UTR       24981863//27773535//22608085 chr18:18530975-18530976(-) m6A 3'UTR       24981863//27773535//22608085 chr18:18530994-18530995(-) m6A 3'UTR       24981863//27773535//22608085 chr18:18531027-18531028(-) m6A 3'UTR       24981863//27773535//22608085 chr18:18547730-18547731(-) m6A CDS       27773535 chr18:18547742-18547743(-) m6A CDS       27773535 chr18:18547784-18547785(-) m6A CDS       24981863//27773535 chr18:18548461-18548462(-) m6A exon//intron       24981863//28052920//27773535//22608085 chr18:18548505-18548506(-) m6A exon//intron       24981863//27773535//22608085 chr18:18548737-18548738(-) m6A CDS//exon       24981863//27773535//22608085 chr18:18548746-18548747(-) m6A CDS//exon       24981863//27773535//22608085 chr18:18548813-18548814(-) m6A CDS//exon       24981863//27773535//22608085 chr18:18549087-18549088(-) m1A CDS//exon       26863196 chr18:18549155-18549156(-) m6A CDS//exon       24981863//27773535//22608085 chr18:18549189-18549190(-) m6A exon//intron       24981863//27773535//22608085 chr18:18550344-18550345(-) m6A CDS//exon       27773535//22608085 chr18:18550395-18550396(-) m6A CDS//exon       24981863//27773535//22608085 chr18:18550439-18550440(-) m6A CDS//exon       24981863//27773535//22608085 chr18:18550469-18550470(-) m6A CDS//exon       24981863//27773535//22608085 chr18:18559884-18559885(-) m6A CDS//exon       24981863//27773535//22608085 chr18:18559912-18559913(-) m6A CDS//exon       24981863//27773535//22608085 chr18:18559938-18559939(-) m6A CDS//exon       24981863//27773535//22608085 chr18:18559952-18559953(-) m6A CDS//exon       24981863//27773535//22608085 chr18:18562771-18562772(-) m6A CDS       24981863//27773535//22608085 chr18:18564376-18564377(-) m6A CDS       27773535 chr18:18564407-18564408(-) m6A CDS       27773535 chr18:18564426-18564427(-) m6A CDS       27773535 chr18:18566946-18566947(-) m6A CDS       27773535//22575960 chr18:18566952-18566953(-) m6A CDS       27773535//22575960 chr18:18566997-18566998(-) m6A CDS       24981863//28052920//27773535//22575960 chr18:18571176-18571177(-) m6A CDS       24981863//28052920//27773535 chr18:18571209-18571210(-) m6A CDS       24981863//28052920//27773535 chr18:18571224-18571225(-) m6A CDS       24981863//28052920//27773535 chr18:18571251-18571252(-) m6A CDS       24981863//28052920//27773535 chr18:18571258-18571259(-) m6A CDS       24981863//28052920//27773535 chr18:18572813-18572814(-) m6A CDS       24981863//28052920//27773535 chr18:18572857-18572858(-) m6A CDS       24981863//27773535 chr18:18586319-18586320(-) m6A CDS       24981863//27773535 chr18:18586349-18586350(-) m6A CDS       24981863//27773535 chr18:18586401-18586402(-) m6A CDS       24981863//27773535 chr18:18586451-18586452(-) m6A CDS       24981863//28052920//27773535//27371828 chr18:18586510-18586511(-) Am CDS       - chr18:18586520-18586521(-) m6A CDS       24981863//27773535//27371828 chr18:18586530-18586531(-) m6A CDS       24981863//27773535//27371828 chr18:18586723-18586724(-) m6A CDS       24981863//27773535//27371828 chr18:18588056-18588057(-) m6A CDS       24981863//27773535//22575960//22608085 chr18:18595419-18595420(-) m6A CDS       24981863//27773535//22608085 chr18:18595424-18595425(-) m6A CDS       24981863//27773535//22608085 chr18:18595431-18595432(-) m6A CDS       24981863//27773535//22608085 chr18:18600161-18600162(-) m6A CDS       24981863//27773535 chr18:18600181-18600182(-) m6A CDS       24981863//27773535 chr18:18603606-18603607(-) m6A CDS       24981863//27773535 chr18:18622636-18622637(-) m6A CDS       22575960 chr18:18624107-18624108(-) m6A CDS       22575960 chr18:18650521-18650522(-) m6A CDS       - chr18:18690808-18690809(-) Cm CDS       - chr18:18690827-18690828(-) m6A CDS       24981863//28052920//27371828//22608085 chr18:18690846-18690847(-) m6A CDS       24981863//28052920//27371828//22608085 chr18:18690857-18690858(-) m6A CDS       24284625//24981863//28052920//27371828//22608085 chr18:18690949-18690950(-) m6A 5'UTR       24284625//24981863//27773535//27371828//27773536//22575960//22608085 chr18:18691003-18691004(-) m6A 5'UTR       24284625//25456834//24981863//27371828//27773536//22575960//22608085 chr18:18691174-18691175(-) m6A 5'UTR       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085 chr18:18691209-18691210(-) m6A 5'UTR       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085 chr18:18691391-18691392(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr18:18691442-18691443(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr18:18691459-18691460(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr18:18691491-18691492(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr18:18691522-18691523(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr18:18691610-18691611(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr18:18691653-18691654(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085 chr18:18691731-18691732(-) m6A 5'UTR       24284625//25456834//24981863//27371828//27773536 chr18:18691743-18691744(-) m6A 5'UTR       24284625//25456834//24981863//27371828//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ebv-miR-BART12	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	ROCK1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome HEK-293 cells     22199352

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	ebv-miR-BART12	Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART12
Interactor2: ROCK1

Evidence Support:

Prediction-Evidence	miRanda//PITA
Support Database	VmiReg