Basic Information:

  VIRBase ID:  

VHID00342113

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2455

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART12:  MIMAT0003423          ITGB8:  NM_002214     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART12	ITGB8
miRBase Accession/Entrez ID	MIMAT0003423	3696
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ITGB8	chr7:20378655(+) A-I      intronic chr7:20378674(+) A-I      intronic chr7:20435998(+) A-I      intronic chr7:20378582(+) A-I      intronic chr7:20378230(+) A-I      intronic chr7:20378165(+) A-I      intronic chr7:20378096(+) A-I      intronic chr7:20378117(+) A-I      intronic chr7:20400977(+) A-I      intronic chr7:20400979(+) A-I      intronic chr7:20400982(+) A-I      intronic chr7:20378722(+) A-I      intronic chr7:20436950(+) A-I      intronic chr7:20436936(+) A-I      intronic chr7:20378656(+) A-I      intronic chr7:20436044(+) A-I      intronic chr7:20378639(+) A-I      intronic chr7:20375758(+) A-I      intronic chr7:20378231(+) A-I      intronic chr7:20375709(+) A-I      intronic chr7:20375684(+) A-I      intronic chr7:20378745(+) A-I      intronic chr7:20378650(+) A-I      intronic chr7:20379491(+) A-I      intronic chr7:20379492(+) A-I      intronic chr7:20379531(+) A-I      intronic chr7:20435935(+) A-I      intronic chr7:20378743(+) A-I      intronic chr7:20379417(+) A-I      intronic chr7:20437111(+) A-I      intronic chr7:20436062(+) A-I      intronic chr7:20378135(+) A-I      intronic chr7:20375679(+) A-I      intronic chr7:20437029(+) A-I      intronic chr7:20378094(+) A-I      intronic chr7:20375889(+) A-I      intronic chr7:20375813(+) A-I      intronic chr7:20436867(+) A-I      intronic chr7:20437032(+) A-I      intronic chr7:20389827(+) A-I      intronic chr7:20378040(+) A-I      intronic chr7:20436979(+) A-I      intronic chr7:20378555(+) A-I      intronic chr7:20375835(+) A-I      intronic chr7:20440741(+) A-I      intronic chr7:20379596(+) A-I      intronic chr7:20435884(+) A-I      intronic chr7:20375839(+) A-I      intronic chr7:20378654(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ITGB8	chr7:20388903(+) A-I intron -    21960545 chr7:20388904(+) A-I intron -    21960545 chr7:20389056(+) A-I intron -    21960545 chr7:20407218(+) A-I intron -    21960545 chr7:20375835(+) A-G intron -    22484847 chr7:20375875(+) G-A intron -    22484847 chr7:20375889(+) A-G intron -    22484847 chr7:20378001(+) T-G intron -    22484847 chr7:20378091(+) A-G intron -    22484847 chr7:20378094(+) A-G intron -    22484847 chr7:20378135(+) A-G intron -    22484847 chr7:20379417(+) A-G intron -    22484847 chr7:20379596(+) A-G intron -    22484847 chr7:20389827(+) A-G intron -    22484847 chr7:20389839(+) C-T intron -    22484847 chr7:20425896(+) G-C intron -    22484847 chr7:20436879(+) A-G intron -    22484847 chr7:20436943(+) A-G intron -    22484847 chr7:20436968(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ITGB8	chr7:20370461-20370462(+) m6A 5'UTR       22575960 chr7:20370549-20370550(+) m6A 5'UTR       25456834//24981863//22575960 chr7:20370587-20370588(+) m6A 5'UTR       25456834//24981863//22575960 chr7:20370639-20370640(+) m6A 5'UTR       - chr7:20370918-20370919(+) m6A 5'UTR//exon       24284625//24209618//25456834//24981863//22575960 chr7:20438651-20438652(+) m6A exon//intron       24981863 chr7:20441398-20441399(+) m6A CDS       24981863 chr7:20441414-20441415(+) m6A CDS       24981863 chr7:20441433-20441434(+) m6A CDS       24981863 chr7:20441458-20441459(+) m6A CDS       24981863 chr7:20441479-20441480(+) m6A CDS       24981863 chr7:20441489-20441490(+) m6A CDS       24981863 chr7:20441514-20441515(+) m6A CDS       24981863 chr7:20449328-20449329(+) m6A CDS       - chr7:20449599-20449600(+) m6A CDS       24284625//24981863//22575960//22608085 chr7:20449634-20449635(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr7:20449648-20449649(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085 chr7:20449705-20449706(+) m6A 3'UTR       24284625//24209618//24981863//22575960 chr7:20449754-20449755(+) m6A 3'UTR       24284625//24209618//24981863//22575960 chr7:20449835-20449836(+) m6A 3'UTR       24284625//24981863//22575960 chr7:20449960-20449961(+) m6A 3'UTR       24284625//24981863 chr7:20450021-20450022(+) m6A 3'UTR       24284625//24981863 chr7:20450069-20450070(+) m6A 3'UTR       24981863 chr7:20450096-20450097(+) m6A 3'UTR       24981863 chr7:20450102-20450103(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	ebv-miR-BART12	Exosome Jurkat-derived T cell line (J77cl20)     21505438
	ITGB8	Exosome Blood     - Nucleus HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	ebv-miR-BART12	Pha-665752       10461815

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART12
Interactor2: ITGB8

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Targetscan
Support Database	RepTar//VmiReg