Basic Information:

  VIRBase ID:  

VHID00340364

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART11-3p:  MIMAT0003422          OTUB1:  NR_003089     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART11-3p	OTUB1
miRBase Accession/Entrez ID	MIMAT0003422	55611
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	HSPC263//OTB1//OTU1

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	OTUB1	chr11:63761975(+) A-I      intronic chr11:63761519(+) A-I      intronic chr11:63761877(+) A-I      intronic chr11:63761494(+) A-I      intronic chr11:63761925(+) A-I      intronic chr11:63761453(+) A-I      intronic chr11:63759537(+) A-I      intronic chr11:63759615(+) A-I      intronic chr11:63760258(+) A-I      intronic chr11:63760225(+) A-I      intronic chr11:63760109(+) A-I      intronic chr11:63760102(+) A-I      intronic chr11:63761905(+) A-I      intronic chr11:63759534(+) A-I      intronic chr11:63761746(+) A-I      intronic chr11:63763358(+) A-I      intronic chr11:63760360(+) A-I      intronic chr11:63760197(+) A-I      intronic chr11:63763359(+) A-I      intronic chr11:63761824(+) A-I      intronic chr11:63761268(+) A-I      intronic chr11:63762987(+) A-I      intronic chr11:63761854(+) A-I      intronic chr11:63755642(+) A-I      intronic chr11:63761269(+) A-I      intronic chr11:63759528(+) A-I      intronic chr11:63760420(+) A-I      intronic chr11:63761891(+) A-I      intronic chr11:63760972(+) A-I      intronic chr11:63760087(+) A-I      intronic chr11:63761209(+) A-I      intronic chr11:63760999(+) A-I      intronic chr11:63760863(+) A-I      intronic chr11:63760934(+) A-I      intronic chr11:63759607(+) A-I      intronic chr11:63760092(+) A-I      intronic chr11:63756645(+) A-I      intronic chr11:63762555(+) A-I      intronic chr11:63760989(+) A-I      intronic chr11:63761527(+) A-I      intronic chr11:63761233(+) A-I      intronic chr11:63759461(+) A-I      intronic chr11:63761745(+) A-I      intronic chr11:63760299(+) A-I      intronic chr11:63760036(+) A-I      intronic chr11:63761825(+) A-I      intronic chr11:63761478(+) A-I      intronic chr11:63761922(+) A-I      intronic chr11:63760297(+) A-I      intronic chr11:63763400(+) A-I      intronic chr11:63762571(+) A-I      intronic chr11:63760338(+) A-I      intronic chr11:63759529(+) A-I      intronic chr11:63761281(+) A-I      intronic chr11:63762526(+) A-I      intronic chr11:63762546(+) A-I      intronic chr11:63757493(+) A-I      intronic chr11:63761744(+) A-I      intronic chr11:63760122(+) A-I      intronic chr11:63756608(+) A-I      intronic chr11:63761934(+) A-I      intronic chr11:63761908(+) A-I      intronic chr11:63760332(+) A-I      intronic chr11:63761015(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	OTUB1	chr11:63756629(+) T-C intron -    22484847 chr11:63757954(+) C-A intron -    22484847 chr11:63759528(+) A-G intron -    22484847 chr11:63759537(+) A-G intron -    22484847 chr11:63761519(+) A-G intron -    22484847 chr11:63761527(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	OTUB1	chr11:63753662-63753663(+) m6A 5'UTR//exon       22575960 chr11:63753691-63753692(+) m6A 5'UTR//exon       22575960 chr11:63753785-63753786(+) m6A 5'UTR//exon//intron       - chr11:63753942-63753943(+) m6A CDS//exon       24981863//26404942 chr11:63764528-63764529(+) m6A CDS//exon//intron       22575960 chr11:63764554-63764555(+) m6A CDS//exon       22575960 chr11:63764692-63764693(+) m6A 3'UTR//CDS//exon       25456834//22575960 chr11:63764713-63764714(+) Cm 3'UTR//CDS//exon       - chr11:63764911-63764912(+) m6A CDS//exon//intron       24284625//25456834//22575960 chr11:63764993-63764994(+) m6A CDS//exon//intron       24284625//24981863//26404942//22575960 chr11:63765069-63765070(+) m6A 3'UTR//exon//intron       24284625//24981863//22575960

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	OTUB1	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus GC cell lines (AGS|HGC-27)     27019636 Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	ebv-miR-BART11-3p	Nvp-aew541       11476171

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART11-3p
Interactor2: OTUB1

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg