Basic Information:

  VIRBase ID:  

VHID00340134

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART11-3p:  MIMAT0003422          PLEKHG3:  NM_001308147     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART11-3p	PLEKHG3
miRBase Accession/Entrez ID	MIMAT0003422	26030
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	ARHGEF43//KIAA0599

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PLEKHG3	chr14:65202181(+) A-I      intronic chr14:65202217(+) A-I      intronic chr14:65201580(+) A-I      intronic chr14:65202224(+) A-I      intronic chr14:65202207(+) A-I      intronic chr14:65200045(+) A-I      intronic chr14:65200032(+) A-I      intronic chr14:65202052(+) A-I      intronic chr14:65202262(+) A-I      intronic chr14:65201630(+) A-I      intronic chr14:65202129(+) A-I      intronic chr14:65202165(+) A-I      intronic chr14:65202189(+) A-I      intronic chr14:65202201(+) A-I      intronic chr14:65201718(+) A-I      intronic chr14:65202148(+) A-I      intronic chr14:65202237(+) A-I      intronic chr14:65202248(+) A-I      intronic chr14:65202134(+) A-I      intronic chr14:65202128(+) A-I      intronic chr14:65202083(+) A-I      intronic chr14:65202260(+) A-I      intronic chr14:65201584(+) A-I      intronic chr14:65202256(+) A-I      intronic chr14:65190319(+) A-I      intronic chr14:65178392(+) A-I      intronic chr14:65202185(+) A-I      intronic chr14:65202274(+) A-I      intronic chr14:65202205(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PLEKHG3	chr14:65197548-65197549(+) m6A CDS//exon       24284625 chr14:65197575-65197576(+) m6A CDS//exon       24284625 chr14:65198183-65198184(+) m6A CDS//exon       24284625 chr14:65198465-65198466(+) m6A CDS//exon       24284625 chr14:65198818-65198819(+) m6A CDS//exon       24284625 chr14:65198837-65198838(+) m6A CDS//exon       24284625 chr14:65198842-65198843(+) m6A CDS//exon       24284625 chr14:65198873-65198874(+) m6A CDS//exon       24284625 chr14:65202400-65202401(+) Am intron       - chr14:65203580-65203581(+) m6A CDS//exon       24209618 chr14:65204052-65204053(+) m6A exon//intron       25456834 chr14:65204751-65204752(+) m6A 5'UTR//intron       24284625//25456834//24981863 chr14:65207763-65207764(+) m6A CDS//exon       24284625//24209618 chr14:65207835-65207836(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65207861-65207862(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65207898-65207899(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65207919-65207920(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65207946-65207947(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65208033-65208034(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65208102-65208103(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65208210-65208211(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65208243-65208244(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65208270-65208271(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65208372-65208373(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22608085 chr14:65208387-65208388(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22608085 chr14:65208389-65208390(+) Am CDS//exon       - chr14:65208418-65208419(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22608085 chr14:65208478-65208479(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:65208489-65208490(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:65208525-65208526(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:65208559-65208560(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:65208607-65208608(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65208630-65208631(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65208978-65208979(+) m6A CDS//exon//intron       24284625//25456834//24981863//26404942//22608085 chr14:65209005-65209006(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22608085 chr14:65209836-65209837(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65209890-65209891(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65210014-65210015(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65210145-65210146(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:65210164-65210165(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:65210179-65210180(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:65210210-65210211(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:65210258-65210259(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:65210296-65210297(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr14:65210344-65210345(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65210353-65210354(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65210380-65210381(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65210407-65210408(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr14:65210468-65210469(+) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//22608085 chr14:65210615-65210616(+) m6A 3'UTR//exon//intron       24284625 chr14:65210790-65210791(+) m6A 3'UTR//exon       24284625 chr14:65213447-65213448(+) m6A 3'UTR       24284625 chr14:65213475-65213476(+) m6A 3'UTR       24284625 chr14:65213510-65213511(+) m6A 3'UTR       24284625 chr14:65216178-65216179(+) m6A 3'UTR       - chr14:65216276-65216277(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	PLEKHG3	Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleus Colon cancer cells     24393600 Nucleus HeLa-S3 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	ebv-miR-BART11-3p	Nvp-aew541       11476171

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART11-3p
Interactor2: PLEKHG3

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//RNAHybrid//Targetscan
Support Database	RepTar//VmiReg