Basic Information:

  VIRBase ID:  

VHID00340025

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2483

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART11-3p:  MIMAT0003422          HIC2:  NM_015094     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART11-3p	HIC2
miRBase Accession/Entrez ID	MIMAT0003422	23119
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	HRG22//ZBTB30//ZNF907

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	HIC2	chr22:21786780(+) A-I      intronic chr22:21786953(+) A-I      intronic chr22:21786826(+) A-I      intronic chr22:21786815(+) A-I      intronic chr22:21786779(+) A-I      intronic chr22:21780813(+) A-I      intronic chr22:21779803(+) A-I      intronic chr22:21780811(+) A-I      intronic chr22:21780251(+) A-I      intronic chr22:21786751(+) A-I      intronic chr22:21779727(+) A-I      intronic chr22:21779787(+) A-I      intronic chr22:21785147(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	HIC2	chr22:21786751(+) A-I intron -    15342557 chr22:21786779(+) A-I intron -    15342557 chr22:21786780(+) A-I intron -    15342557 chr22:21786815(+) A-I intron -    15342557 chr22:21786826(+) A-I intron -    15342557 chr22:21786838(+) A-I intron -    15342557

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	HIC2	chr22:21799236-21799237(+) m6A CDS       24284625 chr22:21799293-21799294(+) m6A CDS       24284625 chr22:21799304-21799305(+) m6A CDS       24284625 chr22:21799344-21799345(+) m6A CDS       24284625//24209618//22608085 chr22:21799434-21799435(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr22:21799440-21799441(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr22:21799476-21799477(+) m6A CDS       24284625//25456834//24981863//22608085 chr22:21799597-21799598(+) m6A CDS       24284625//25456834//24981863//22608085 chr22:21799783-21799784(+) m6A CDS       25456834//24981863//22608085 chr22:21799926-21799927(+) m6A CDS       24284625//25456834//22608085 chr22:21800121-21800122(+) m6A CDS       24284625//25456834//24981863//22608085 chr22:21800295-21800296(+) m6A CDS       24284625//25456834//24981863//22608085 chr22:21800406-21800407(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr22:21800499-21800500(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr22:21800570-21800571(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr22:21800618-21800619(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr22:21800652-21800653(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr22:21800720-21800721(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr22:21800730-21800731(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr22:21800944-21800945(+) m6A CDS       24284625//25456834//24981863//22608085 chr22:21801041-21801042(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr22:21801077-21801078(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr22:21801120-21801121(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr22:21801189-21801190(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr22:21801327-21801328(+) m6A 3'UTR       25456834 chr22:21803060-21803061(+) m6A 3'UTR       24284625 chr22:21803067-21803068(+) m6A 3'UTR       24284625 chr22:21803072-21803073(+) m6A 3'UTR       24284625 chr22:21803108-21803109(+) m6A 3'UTR       24284625 chr22:21803123-21803124(+) m6A 3'UTR       24284625 chr22:21803131-21803132(+) m6A 3'UTR       24284625 chr22:21803323-21803324(+) m6A 3'UTR       - chr22:21803332-21803333(+) m6A 3'UTR       - chr22:21803655-21803656(+) m6A 3'UTR       24981863 chr22:21803701-21803702(+) m6A 3'UTR       24981863 chr22:21804427-21804428(+) m6A 3'UTR       22608085 chr22:21804484-21804485(+) m6A 3'UTR       24284625//25456834//24981863//22608085 chr22:21804543-21804544(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr22:21804570-21804571(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr22:21804617-21804618(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085 chr22:21804726-21804727(+) m6A 3'UTR       24284625//25456834//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	HIC2	Chromatin K562 cells     - Cytosol K562 cells     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	ebv-miR-BART11-3p	Nvp-aew541       11476171

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART11-3p
Interactor2: HIC2

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA//Rep//Targetscan
Support Database	RepTar//VmiReg