Basic Information:
VIRBase ID: VHID00339853
Virus: Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)
Host: Homo sapiens
Confidence Score: 0.9630
Interaction Type: Virus-Host interaction
Predicted Binding:
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Interactor Information:
Interactor1
Interactor2
Symbol
ebv-miR-BART11-3p
BCL2L11
miRBase Accession/Entrez ID
MIMAT0003422
10018
Organism
Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)
Homo sapiens
Category
miRNA
mRNA
Alias
-
BAM//BIM//BOD
RNA Editing:
Resource
Symbol
Editing Position
Change
Genetic Region
RADAR
BCL2L11
RNA Modification:
Resource
Symbol
ModificationPosition
Type
Genomic Context
PMID
RMBase
BCL2L11
RNA Localization:
Resource
Symbol
Subcellular Localization
Tissue or Cell Line
PMID
RNALocate
BCL2L11
Related Drug Information:
Resource
Symbol
Drug Name
PubChem ID
RNAactDrug
ebv-miR-BART11-3p
Interaction Network (The top 100 interactions) :
Interactor1: ebv-miR-BART11-3p
Interactor2: BCL2L11
Evidence Support:
Strong-Evidence
Luciferase reporter assay//Northern blot//qRT-PCR
Prediction-Evidence
miRanda//PITA
Support Database
ViRBase//VmiReg
References:
PMID
21333317
Target region
3'UTR
Source
ViRBase
Interactor1 expression
None
Tissue or cell line
AGS cells//C666-1 cells
Interactor2 expression
Downregulation
Description
Analysis of the BimEL protein levels in cells expressing the miRNAs revealed that its expression was affected by several of the individual miRNAs with cell lines expressing miR-BART1, 3, 9, 11 and 12 all having decreased BimEL levels (Figure 6B and C).