Basic Information:

  VIRBase ID:  

VHID00339736

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.2381

  Interaction Type:  

Virus-Host interaction

  Predicted Binding:

 

      ebv-miR-BART11-3p:  MIMAT0003422          MAPKAPK2:  NM_032960     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ebv-miR-BART11-3p	MAPKAPK2
miRBase Accession/Entrez ID	MIMAT0003422	9261
Organism	Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)	Homo sapiens
Category	miRNA	mRNA
Alias	-	MAPKAP-K2//MK-2//MK2

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MAPKAPK2	chr1:206869524(+) A-I      intronic chr1:206869480(+) A-I      intronic chr1:206869526(+) A-I      intronic chr1:206895611(+) A-I      intronic chr1:206886159(+) A-I      intronic chr1:206884725(+) A-I      intronic chr1:206893942(+) A-I      intronic chr1:206895231(+) A-I      intronic chr1:206895225(+) A-I      intronic chr1:206886056(+) A-I      intronic chr1:206888119(+) A-I      intronic chr1:206886190(+) A-I      intronic chr1:206895255(+) A-I      intronic chr1:206869460(+) A-I      intronic chr1:206862041(+) A-I      intronic chr1:206899671(+) A-I      intronic chr1:206893809(+) A-I      intronic chr1:206901046(+) A-I      intronic chr1:206884696(+) A-I      intronic chr1:206886161(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MAPKAPK2	chr1:206869460(+) A-I intron -    22327324 chr1:206884664(+) A-I intron -    21960545 chr1:206886055(+) A-I intron -    21960545 chr1:206886135(+) A-I intron -    21960545 chr1:206898570(+) A-I intron -    21960545 chr1:206869460(+) A-G intron -    21725310 chr1:206862041(+) A-G intron -    22484847 chr1:206884696(+) A-G intron -    22484847 chr1:206884725(+) A-G intron -    22484847 chr1:206886190(+) A-G intron -    22484847 chr1:206893809(+) A-G intron -    22484847 chr1:206901046(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MAPKAPK2	chr1:206858402-206858403(+) m6A 5'UTR       24209618 chr1:206858475-206858476(+) m6A 5'UTR       24209618 chr1:206858829-206858830(+) m6A CDS       - chr1:206902411-206902412(+) Am CDS//exon       - chr1:206904543-206904544(+) m6A CDS       - chr1:206904680-206904681(+) m6A exon//intron       - chr1:206905626-206905627(+) m6A 3'UTR//intron       24284625 chr1:206905698-206905699(+) m6A 3'UTR//intron       24284625 chr1:206905767-206905768(+) m6A 3'UTR//intron       24284625 chr1:206906091-206906092(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:206906135-206906136(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:206906140-206906141(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:206906187-206906188(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:206906289-206906290(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr1:206906342-206906343(+) m6A 3'UTR       24284625//24209618//24981863//22575960 chr1:206906438-206906439(+) m6A 3'UTR       24284625//24981863 chr1:206906830-206906831(+) m6A 3'UTR       - chr1:206906914-206906915(+) m6A 3'UTR       - chr1:206906919-206906920(+) m6A 3'UTR       - chr1:206907314-206907315(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	MAPKAPK2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome HEK-293 cells     22199352

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	ebv-miR-BART11-3p	Nvp-aew541       11476171

Interaction Network (The top 100 interactions):

Interactor1: ebv-miR-BART11-3p
Interactor2: MAPKAPK2

Evidence Support:

Prediction-Evidence	cRep//miRanda//PITA
Support Database	RepTar//VmiReg